Diabetes and exercise
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Diabetes and exercise. / Richter, Erik A.; Ruderman, N B; Schneider, S H.
In: American Journal of Medicine, Vol. 70, No. 1, 1981, p. 201-209.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Diabetes and exercise
AU - Richter, Erik A.
AU - Ruderman, N B
AU - Schneider, S H
PY - 1981
Y1 - 1981
N2 - This review describes (1) the metabolic and hormonal response to exercise in normal and diabetic man, and (2) the potential benefits of physical training in diabetes. Whereas in normal man plasma glucose varies little during exercise, the insulin-dependent diabetic subject may experience an increase in plasma glucose, a modest decrease or a marked decrease which can result in symptomatic hypoglycemia. Evidence is reviewed that the glycemic response depends on the ambient plasma concentration of insulin and that this may be influenced by an effect of exercise on the absorbtion of insulin from its site of injection. The response to exercise of noninsulin-dependent diabetic subjects and of diabetic subjects with autonomic neuropathy is also described. Physical training improves glucose tolerance in some noninsulin-dependent diabetic subjects and in insulin-dependent patients, it may diminish insulin requirements. It may also have a role in retarding the development of cardiovascular complications. Physical training is not totally innocuous, however, and in many patients with diabetes special precautions are required.
AB - This review describes (1) the metabolic and hormonal response to exercise in normal and diabetic man, and (2) the potential benefits of physical training in diabetes. Whereas in normal man plasma glucose varies little during exercise, the insulin-dependent diabetic subject may experience an increase in plasma glucose, a modest decrease or a marked decrease which can result in symptomatic hypoglycemia. Evidence is reviewed that the glycemic response depends on the ambient plasma concentration of insulin and that this may be influenced by an effect of exercise on the absorbtion of insulin from its site of injection. The response to exercise of noninsulin-dependent diabetic subjects and of diabetic subjects with autonomic neuropathy is also described. Physical training improves glucose tolerance in some noninsulin-dependent diabetic subjects and in insulin-dependent patients, it may diminish insulin requirements. It may also have a role in retarding the development of cardiovascular complications. Physical training is not totally innocuous, however, and in many patients with diabetes special precautions are required.
KW - Diabetes Mellitus
KW - Diabetic Neuropathies
KW - Energy Metabolism
KW - Glucose
KW - Humans
KW - Hypoglycemia
KW - Insulin
KW - Liver
KW - Muscles
KW - Physical Exertion
M3 - Review
C2 - 7006392
VL - 70
SP - 201
EP - 209
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 1
ER -
ID: 154760535