Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds
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- chem201704732
Final published version, 3.69 MB, PDF document
Direct C−H difluoromethylation of electron-deficient positions in nitrogen-containing heterocycles is attained by difluoromethyl radicals generated in-situ from difluoroacetic acid under silver-catalyzed oxidative decarboxylation. Control of the reaction temperature permits either mono- or disubstitution. More information can be found in the Communication by J. Nielsen et al. (DOI: 10.1002/chem.201704261).
Original language | English |
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Journal | Chemistry - A European Journal |
Number of pages | 2 |
ISSN | 0947-6539 |
Publication status | Published - 25 Oct 2017 |
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ID: 185005538