Complement deficiencies in selected groups of patients with meningococcal disease

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Complement deficiencies in selected groups of patients with meningococcal disease. / Nielsen, Hans E.; Koch, Claus; Magnussen, Pascal; Lind, Inga.

In: Scandinavian Journal of Infectious Diseases, Vol. 21, No. 4, 01.01.1989, p. 389-396.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nielsen, HE, Koch, C, Magnussen, P & Lind, I 1989, 'Complement deficiencies in selected groups of patients with meningococcal disease', Scandinavian Journal of Infectious Diseases, vol. 21, no. 4, pp. 389-396. https://doi.org/10.3109/00365548909167442

APA

Nielsen, H. E., Koch, C., Magnussen, P., & Lind, I. (1989). Complement deficiencies in selected groups of patients with meningococcal disease. Scandinavian Journal of Infectious Diseases, 21(4), 389-396. https://doi.org/10.3109/00365548909167442

Vancouver

Nielsen HE, Koch C, Magnussen P, Lind I. Complement deficiencies in selected groups of patients with meningococcal disease. Scandinavian Journal of Infectious Diseases. 1989 Jan 1;21(4):389-396. https://doi.org/10.3109/00365548909167442

Author

Nielsen, Hans E. ; Koch, Claus ; Magnussen, Pascal ; Lind, Inga. / Complement deficiencies in selected groups of patients with meningococcal disease. In: Scandinavian Journal of Infectious Diseases. 1989 ; Vol. 21, No. 4. pp. 389-396.

Bibtex

@article{befbc52188844488bfd9566df48f9526,
title = "Complement deficiencies in selected groups of patients with meningococcal disease",
abstract = "We have examined 125 individuals who have earlier had meningococcal (mgc) disease. They belonged to one or more of the following groups: (1) 2 or more cases of mgc disease in the same family; (2) individuals with 2 episodes of mgc disease or with 1 episode of mgc disease and 1 or more episodes of purulent meningitis of another aetiology; and (3) infections with Neisseria meningitidis belonging to serogroups that are uncommon as causes of disease and presumably low-virulent (W-135, 29E, X, Y). Among these we found 15 complement (C)-deficient individuals (12% The prevalence of C deficiency in the groups above was 7% 41% and 19% respectively. The first group (family cases), is very heterogeneous and may be further subdivided into 2 groups: families whose members fell ill within an interval of 30 days (in these the prevalence of C deficiency was 2% and families in which the interval between mgc disease cases exceeded 30 days (in those the prevalence of C deficiency was 14% We found a predominance of defects of the initiation pathways, with properdin deficiency being the most common.",
author = "Nielsen, {Hans E.} and Claus Koch and Pascal Magnussen and Inga Lind",
year = "1989",
month = jan,
day = "1",
doi = "10.3109/00365548909167442",
language = "English",
volume = "21",
pages = "389--396",
journal = "Scandinavian Journal of Infectious Diseases, Supplement",
issn = "0300-8878",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Complement deficiencies in selected groups of patients with meningococcal disease

AU - Nielsen, Hans E.

AU - Koch, Claus

AU - Magnussen, Pascal

AU - Lind, Inga

PY - 1989/1/1

Y1 - 1989/1/1

N2 - We have examined 125 individuals who have earlier had meningococcal (mgc) disease. They belonged to one or more of the following groups: (1) 2 or more cases of mgc disease in the same family; (2) individuals with 2 episodes of mgc disease or with 1 episode of mgc disease and 1 or more episodes of purulent meningitis of another aetiology; and (3) infections with Neisseria meningitidis belonging to serogroups that are uncommon as causes of disease and presumably low-virulent (W-135, 29E, X, Y). Among these we found 15 complement (C)-deficient individuals (12% The prevalence of C deficiency in the groups above was 7% 41% and 19% respectively. The first group (family cases), is very heterogeneous and may be further subdivided into 2 groups: families whose members fell ill within an interval of 30 days (in these the prevalence of C deficiency was 2% and families in which the interval between mgc disease cases exceeded 30 days (in those the prevalence of C deficiency was 14% We found a predominance of defects of the initiation pathways, with properdin deficiency being the most common.

AB - We have examined 125 individuals who have earlier had meningococcal (mgc) disease. They belonged to one or more of the following groups: (1) 2 or more cases of mgc disease in the same family; (2) individuals with 2 episodes of mgc disease or with 1 episode of mgc disease and 1 or more episodes of purulent meningitis of another aetiology; and (3) infections with Neisseria meningitidis belonging to serogroups that are uncommon as causes of disease and presumably low-virulent (W-135, 29E, X, Y). Among these we found 15 complement (C)-deficient individuals (12% The prevalence of C deficiency in the groups above was 7% 41% and 19% respectively. The first group (family cases), is very heterogeneous and may be further subdivided into 2 groups: families whose members fell ill within an interval of 30 days (in these the prevalence of C deficiency was 2% and families in which the interval between mgc disease cases exceeded 30 days (in those the prevalence of C deficiency was 14% We found a predominance of defects of the initiation pathways, with properdin deficiency being the most common.

UR - http://www.scopus.com/inward/record.url?scp=0024459070&partnerID=8YFLogxK

U2 - 10.3109/00365548909167442

DO - 10.3109/00365548909167442

M3 - Journal article

C2 - 2511621

AN - SCOPUS:0024459070

VL - 21

SP - 389

EP - 396

JO - Scandinavian Journal of Infectious Diseases, Supplement

JF - Scandinavian Journal of Infectious Diseases, Supplement

SN - 0300-8878

IS - 4

ER -

ID: 224709998