Clinical risk factors, DNA variants, and the development of type 2 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

  • Valeriya Lyssenko
  • Jonsson, Anna Elisabet
  • Peter Almgren
  • Nicoló Pulizzi
  • Bo Isomaa
  • Tiinamaija Tuomi
  • Göran Berglund
  • David Altshuler
  • Peter Nilsson
  • Leif Groop
Type 2 diabetes mellitus is thought to develop from an interaction between environmental and genetic factors. We examined whether clinical or genetic factors or both could predict progression to diabetes in two prospective cohorts.
Original languageEnglish
JournalNew England Journal of Medicine
Volume359
Issue number21
Pages (from-to)2220-32
Number of pages13
ISSN0028-4793
DOIs
Publication statusPublished - 20 Nov 2008

    Research areas

  • Adult, Blood Glucose, Blood Pressure, Body Mass Index, Diabetes Mellitus, Type 2, Female, Finland, Follow-Up Studies, Genetic Predisposition to Disease, Genotype, Humans, Insulin, Logistic Models, Male, Middle Aged, Odds Ratio, Polymorphism, Single Nucleotide, Proteins, ROC Curve, Risk Factors, Smoking, Sweden, Transaminases

ID: 46404618