Cirrhotic cardiomyopathy: a pathophysiological review of circulatory dysfunction in liver disease

Research output: Contribution to journalJournal articleResearchpeer-review

The systemic circulation in patients with cirrhosis is hyperdynamic with an increased cardiac output and heart rate and a reduced systemic vascular resistance as the most pronounced alterations. The concomitant cardiac dysfunction has recently been termed "cirrhotic cardiomyopathy", which is an entity different from that seen in alcoholic heart muscle disease. Clinically, these patients present with sodium fluid retention and strain often unmasks the presence of latent heart failure. No specific treatment can yet be recommended but caution should be used with respect to procedures that may stress the heart such as shunt implantation and liver transplantation.
Original languageEnglish
JournalHeart
Volume87
Issue number1
Pages (from-to)9-15
Number of pages6
ISSN1355-6037
Publication statusPublished - 2002

Bibliographical note

Keywords: Autonomic Nervous System Diseases; Blood Pressure; Cardiomegaly; Coronary Circulation; Heart Conduction System; Heart Diseases; Humans; Liver Cirrhosis; Liver Transplantation; Portasystemic Shunt, Surgical; Ventricular Dysfunction, Left

ID: 18151485