Characterizing incidental mass lesions in abdominal dual-energy CT compared to conventional contrast-enhanced CT
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Characterizing incidental mass lesions in abdominal dual-energy CT compared to conventional contrast-enhanced CT. / Xu, Jack Junchi; Ulriksen, Peter Sommer; Bjerrum, Camilla Wium; Achiam, Michael Patrick; Resch, Timothy Andrew; Lönn, Lars; Lindskov Hansen, Kristoffer.
In: Acta Radiologica, Vol. 64, No. 3, 2023, p. 945–950.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Characterizing incidental mass lesions in abdominal dual-energy CT compared to conventional contrast-enhanced CT
AU - Xu, Jack Junchi
AU - Ulriksen, Peter Sommer
AU - Bjerrum, Camilla Wium
AU - Achiam, Michael Patrick
AU - Resch, Timothy Andrew
AU - Lönn, Lars
AU - Lindskov Hansen, Kristoffer
N1 - Publisher Copyright: © The Foundation Acta Radiologica 2022.
PY - 2023
Y1 - 2023
N2 - Background: Incidental findings are common in abdominal computed tomography (CT) and often warrant further investigations with economic implications as well as implications for patients. Purpose: To evaluate the potential of dual-energy CT (DECT) in the identification and/or characterization of abdominal incidental mass lesions compared to conventional contrast-enhanced CT Material and Methods: This retrospective study from a major tertiary hospital included 96 patients, who underwent contrast-enhanced abdominal DECT. Incidental lesions in adrenals, kidneys, liver, and pancreas were evaluated by two board-certified abdominal radiologists. Observer 1 only had access to standard CT reconstructions, while observer 2 had access to standard CT as well as DECT reconstructions. Disagreements were resolved by consensus review and used as a reference for observers using McNemar's test Results: Observers 1 and 2 identified a total of 40 and 34 findings, respectively. Furthermore, observer 1 registered 13 lesions requiring follow-up, of which seven (two renal and five adrenal lesions) were resolved following consensus review using DECT (P = 0.008). The inter-observer agreement was near perfect (κ = 0.82). Conclusion: DECT has the potential to improve the immediate characterization of incidental findings when compared to conventional CT for abdominal imaging.
AB - Background: Incidental findings are common in abdominal computed tomography (CT) and often warrant further investigations with economic implications as well as implications for patients. Purpose: To evaluate the potential of dual-energy CT (DECT) in the identification and/or characterization of abdominal incidental mass lesions compared to conventional contrast-enhanced CT Material and Methods: This retrospective study from a major tertiary hospital included 96 patients, who underwent contrast-enhanced abdominal DECT. Incidental lesions in adrenals, kidneys, liver, and pancreas were evaluated by two board-certified abdominal radiologists. Observer 1 only had access to standard CT reconstructions, while observer 2 had access to standard CT as well as DECT reconstructions. Disagreements were resolved by consensus review and used as a reference for observers using McNemar's test Results: Observers 1 and 2 identified a total of 40 and 34 findings, respectively. Furthermore, observer 1 registered 13 lesions requiring follow-up, of which seven (two renal and five adrenal lesions) were resolved following consensus review using DECT (P = 0.008). The inter-observer agreement was near perfect (κ = 0.82). Conclusion: DECT has the potential to improve the immediate characterization of incidental findings when compared to conventional CT for abdominal imaging.
KW - abdomen/gastrointestinal
KW - computed tomography
KW - Dual-energy computed tomography
U2 - 10.1177/02841851221116306
DO - 10.1177/02841851221116306
M3 - Journal article
C2 - 35918808
AN - SCOPUS:85135446420
VL - 64
SP - 945
EP - 950
JO - Acta Radiologica - Series Diagnosis
JF - Acta Radiologica - Series Diagnosis
SN - 0365-5954
IS - 3
ER -
ID: 321875302