TY - JOUR

T1 - Cerebrovascular damage in hypertension

AU - Strandgaard, S

AU - Paulson, O B

PY - 1995/2

Y1 - 1995/2

N2 - Hypertension causes marked adaptive changes in the cerebral circulation. The excess risk of stroke associated with hypertension is eliminated in controlled trials of antihypertensive treatment. Such treatment may even prevent transient ischaemic attacks in the elderly. In rare cases, overzealous antihypertensive treatment may cause cerebral ischaemia, especially in the initial treatment of very severe hypertension. Headache may occasionally be caused by severe hypertension, which may also lead to the rare syndrome of acute hypertensive encephalopathy. Finally, the importance of white-matter lesions, or leukoaraiosis, in hypertension is not yet fully established.

AB - Hypertension causes marked adaptive changes in the cerebral circulation. The excess risk of stroke associated with hypertension is eliminated in controlled trials of antihypertensive treatment. Such treatment may even prevent transient ischaemic attacks in the elderly. In rare cases, overzealous antihypertensive treatment may cause cerebral ischaemia, especially in the initial treatment of very severe hypertension. Headache may occasionally be caused by severe hypertension, which may also lead to the rare syndrome of acute hypertensive encephalopathy. Finally, the importance of white-matter lesions, or leukoaraiosis, in hypertension is not yet fully established.

KW - Aged

KW - Antihypertensive Agents/therapeutic use

KW - Brain Diseases/etiology

KW - Brain Ischemia/etiology

KW - Cerebrovascular Circulation

KW - Cerebrovascular Disorders/etiology

KW - Controlled Clinical Trials as Topic

KW - Humans

KW - Hypertension/complications

KW - Ischemic Attack, Transient/etiology

M3 - Review

C2 - 7606637

VL - 2

SP - 34

EP - 39

JO - Journal of Cardiovascular Risk

JF - Journal of Cardiovascular Risk

SN - 1350-6277

IS - 1

ER -