Bilateral Diabetic Papillopathy and Metabolic Control
Research output: Contribution to journal › Journal article › Research › peer-review
OBJECTIVE: The pathogenesis of diabetic papillopathy largely is unknown, but case reports suggest that it may follow rapidly improved metabolic control. The present study was designed to investigate this hypothesis. DESIGN: Retrospective case-control study. PARTICIPANTS: Two thousand sixty-six patients with type 1 diabetes. METHODS: Review of clinical, photographic, and clinical chemistry records from a large diabetology and ophthalmology unit between 2001 and 2008. MAIN OUTCOME MEASURES: Simultaneous, bilateral diabetic papillopathy. RESULTS: The mean follow-up was 4.9 years. During 10 020 patient-years of observation, bilateral diabetic papillopathy developed in 5 patients. During the year preceding this incident, all 5 patients had experienced a decrease in glycosylated hemoglobin A(1c) (HbA(1C)) at a maximum rate of -2.5 (mean) percentage points per quarter year, which was significantly different from the changes in HbA(1C) observed in the remainder of the study population (P
Original language | English |
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Journal | Ophthalmology |
Volume | 117 |
Issue number | 11 |
Pages (from-to) | 214-217 |
Number of pages | 4 |
ISSN | 0161-6420 |
DOIs | |
Publication status | Published - 15 Jun 2010 |
ID: 34083064