Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent
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Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent. / Berthelsen, Ragna; Nielsen, Carsten Uhd; Brodin, Birger.
In: Journal of Pharmacy and Pharmacology, Vol. 65, No. 7, 07.2013, p. 970-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent
AU - Berthelsen, Ragna
AU - Nielsen, Carsten Uhd
AU - Brodin, Birger
N1 - © 2013 Royal Pharmaceutical Society.
PY - 2013/7
Y1 - 2013/7
N2 - Transepithelial di/tripeptide transport in enterocytes occurs via the apical proton-coupled peptide transporter, hPEPT1 (SLC15A1) and a basolateral peptide transporter, which has only been characterized functionally. In this study we examined the pH dependency, substrate uptake kinetics and substrate specificity of the transporter.
AB - Transepithelial di/tripeptide transport in enterocytes occurs via the apical proton-coupled peptide transporter, hPEPT1 (SLC15A1) and a basolateral peptide transporter, which has only been characterized functionally. In this study we examined the pH dependency, substrate uptake kinetics and substrate specificity of the transporter.
U2 - 10.1111/jphp.12061
DO - 10.1111/jphp.12061
M3 - Journal article
C2 - 23738724
VL - 65
SP - 970
EP - 979
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
SN - 0022-3573
IS - 7
ER -
ID: 46203180