Aspergillus flavus Infections in Children with Leukemia despite Liposomal Amphotericin-B Prophylaxis
Research output: Contribution to journal › Journal article › Research › peer-review
Liposomal amphotericin-B (L-AmB) prophylaxis is used in children with leukemia when azoles are contraindicated, but its effect is debated. We reviewed cases of invasive aspergillosis despite L-AmB 2.5 mg/kg twice weekly in children with high-risk leukemia during 2012-2019. Ten (16%) of 62 children had proven or probable aspergillosis. Thus, L-AmB prophylaxis offered insufficient protection for Aspergillus, in particular for Aspergillus flavus.
Original language | English |
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Journal | Pediatric Infectious Disease Journal |
Volume | 40 |
Issue number | 8 |
Pages (from-to) | 749-752 |
Number of pages | 4 |
ISSN | 0891-3668 |
DOIs | |
Publication status | Published - 2021 |
Bibliographical note
Publisher Copyright:
© 2021 Wolters Kluwer Health, Inc. All rights reserved.
- Aspergillus flavus, invasive fungal disease, pediatric leukemia, prophylaxis
Research areas
ID: 275774357