Adverse events in transcatheter interventions for congenital heart disease: a population-based long-term study
Research output: Contribution to journal › Journal article › Research › peer-review
OBJECTIVE: Few studies have reported procedure complications or adverse events for transcatheter interventions in unselected congenital heart disease cohorts. We report our 23-year experience with transcatheter interventions in congenital heart disease and examine predictors for adverse events.
DESIGN AND SETTING: This study was a population-based cohort study of children and adults with congenital heart disease, covering a population of 3 million inhabitants in western Denmark. Adverse events were subdivided into 5 levels according to their severity. Procedure-type risk category, age, weight, and year of procedure were included in multivariate logistic models to identify risk factors for adverse events.
RESULTS: Between 1990 and 2012, 1595 patients had 1878 catheter-based interventions performed. We identified 241 adverse events, corresponding to 13% of the procedures; 58 (3%) were considered to be of high severity. During the study period, there was an increase in number of procedures per year (P < .001) and a decrease in frequency of adverse events (P = .01). Procedure-type categories 3 and 4 had increased risk of adverse events when compared with category 2, with odds ratios of 1.7 (95% confidence interval [CI]: 1.2-2.3) for category 3 and 2.3 for category 4 (95% CI: 1.4-3.6). Age and weight at catheterization were not independently associated with adverse events.
CONCLUSIONS: We found an increase in number of procedures over time and a decrease in frequency of adverse events. Higher procedure-type risk categories were associated with increased risk of adverse events.
Original language | English |
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Journal | Congenital Heart Disease |
Volume | 10 |
Issue number | 2 |
Pages (from-to) | 153-8 |
Number of pages | 6 |
ISSN | 1747-079X |
DOIs | |
Publication status | Published - 10 Sep 2014 |
- Adolescent, Cardiac Catheterization/adverse effects, Cardiac Surgical Procedures/adverse effects, Child, Child, Preschool, Cohort Studies, Female, Heart Defects, Congenital/surgery, Heart Diseases/congenital, Humans, Infant, Infant, Newborn, Male, Postoperative Complications/epidemiology, Prognosis, Retrospective Studies, Time Factors
Research areas
ID: 242611344