Title: Intestinal epigenetics of preterm neonates
The PhD projects are aimed:
(1) To characterize the intestinal epigenetic pattern in response to preterm birth (relative to birth at full term).
(2) To investigate the intestinal epigenetic pattern in preterm piglets, as related to different feeding modes (TPN versus enteral—formula and colostrum).
(3) To investigate the intestinal epigenetic pattern in preterm piglets, as related to differences in bacterial colonization (antibiotic versus control treatment).
(4) To translate the findings from piglets into infants. In this slightly more exploratory work package, we will seek for potential replication of preterm piglet intestinal results on preterm infant fecal sample.