Oluf Borbye Pedersen

Oluf Borbye Pedersen

Visiting professor, Clinical Professor

Member of:

  • Internal medicine: infection medicine

  • Internal Medicine: Endocrinology


  1. 2006
  2. Published

    Molekylaer patogenese ved monogen og polygen fedme

    Larsen, P. J., Echwald, S. M., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2006, In: Ugeskrift for Laeger. 168, 2, p. 152-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy

    Rossing, Peter, Rossing, K., Gaede, P., Pedersen, Oluf Borbye & Parving, H., 2006, In: Diabetes Care. 29, 5, p. 1024-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    PROactive study

    Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2006, In: Lancet. 367, 9504, p. 23-4; author reply 26-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study

    van Hove, E. C., Hansen, Torben, Dekker, J. M., Reiling, E., Nijpels, G., Jørgensen, T., Borch-Johnsen, K., Hamid, Y. H., Heine, R. J., Pedersen, Oluf Borbye, Maassen, J. A. & hart, L. M., 2006, In: Diabetes. 55, 11, p. 3193-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects

    Torekov, Signe Sørensen, Larsen, L. H., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2006, In: Diabetologia. 49, 11, p. 2653-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites

    Jensen, D. P., Urhammer, S. A., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Molecular Genetics and Metabolism. 89, 4, p. 360-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2005
  9. Published

    PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites

    Andersen, G., Wegner, L., Jensen, D. P., Glümer, C., Tarnow, L., Drivsholm, Thomas, Poulsen, P., Hansen, S. K., Nielsen, E. D., Ek, J., Mouritzen, P., Vaag, A., Parving, H., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2005, In: Hypertension. 45, 4, p. 565-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites

    Rose, C. S., Ek, J., Urhammer, S. A., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Diabetes. 54, 10, p. 3026-31 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians

    Anuradha, S., Radha, V., Deepa, R., Hansen, Torben, Carstensen, Bendix, Pedersen, Oluf Borbye & Mohan, V., 2005, In: Diabetes Care. 28, 10, p. 2430-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes

    Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

    hart, L. M., Hansen, Torben, Rietveld, I., Dekker, J. M., Nijpels, G., Janssen, G. M. C., Arp, P. A., Uitterlinden, A. G., Jørgensen, T., Borch-Johnsen, K., Pols, H. A. P., Pedersen, Oluf Borbye, van Duijn, C. M., Heine, R. J. & Maassen, J. A., 2005, In: Diabetes. 54, 6, p. 1892-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetics of type 2 diabetes mellitus: status and perspectives

    Hansen, L. & Pedersen, Oluf Borbye, 2005, In: Diabetes, Obesity and Metabolism. 7, 2, p. 122-35 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mutation analysis of the MCHR1 gene in human obesity

    Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., Sørensen, T. I. A. & 11 others, Astrup, A., Larsen, L. H., Pedersen, Oluf Borbye, Eberlé, D., Clément, K., Blundell, J., Wabitsch, M., Schäfer, H., Platzer, M., Hinney, A. & Hebebrand, J., 2005, In: European Journal of Endocrinology. 152, 6, p. 851-62 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes

    Larsen, L. H., Gjesing, A. P., Sørensen, Thorkild I.A., Hamid, Y. H., Echwald, S. M., Toubro, S., Black, E., Astrup, A., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Clinical Biochemistry. 38, 5, p. 420-424 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity

    Larsen, L. H., Echwald, S. M., Sørensen, Thorkild I.A., Andersen, T., Wulff, B. S. & Pedersen, Oluf Borbye, 2005, In: The Journal of Clinical Endocrinology & Metabolism. 90, 1, p. 219-224 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

    Neve, B., Fernandez-Zapico, M. E., Ashkenazi-Katalan, V., Dina, C., Hamid, Y. H., Joly, E., Vaillant, E., Benmezroua, Y., Durand, E., Bakaher, N., Delannoy, V., Vaxillaire, M., Cook, T., Dallinga-Thie, G. M., Jansen, H., Charles, M-A., Clément, K., Galan, P., Hercberg, S., Helbecque, N. & 7 others, Charpentier, G., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Urrutia, R., Melloul, D. & Froguel, P., 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4807-12 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits

    Nielsen, E. D., Hansen, L., Stissing, T., Yanagisawa, K., Borch-Johnsen, K., Poulsen, P., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Molecular Medicine. 83, 5, p. 353-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men

    Buemann, B., Black, E., Holst, C., Toubro, S., Echwald, S., Pedersen, Oluf Borbye, Astrup, A. & Sørensen, Thorkild I.A., 2005, In: Obesity Research. 13, 5, p. 862-867 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

    Ek, J., Rose, C. S., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3054-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population

    Lauenborg, J., Mathiesen, Elisabeth, Hansen, Torben, Glümer, C., Jørgensen, T., Borch-Johnsen, K., Hornnes, P., Pedersen, Oluf Borbye & Damm, Peter, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4004-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity

    Andersen, K. L., Echwald, S. M., Larsen, L. H., Hamid, Y. H., Glumer, C., Jørgensen, T., Borch-Johnsen, K., Andersen, T., Sørensen, Thorkild I.A., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 1, p. 225-230 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2004
  25. Published

    Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus

    Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects

    Nielsen, E. D., Hansen, L., Lajer, M., Andersen, K. L., Echwald, S. M., Urhammer, S. A., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Clinical Biochemistry. 37, 8, p. 660-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

    Højlund, K., Hansen, Torben, Lajer, M., Henriksen, J. E., Levin, K., Lindholm, J., Pedersen, Oluf Borbye & Beck-Nielsen, H., 2004, In: Diabetes. 53, 6, p. 1592-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes

    Hansen, L., Gaster, M., Oakeley, E. J., Brusgaard, K., Damsgaard Nielsen, E., Beck-Nielsen, H., Pedersen, Oluf Borbye & Hemmings, B. A., 2004, In: Biochemical and Biophysical Research Communications. 323, 2, p. 685-95 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Grey-box modelling of pharmacokinetic/pharmacodynamic systems

    Tornøe, C. W., Jacobsen, Judith Lone, Pedersen, Oluf Borbye, Hansen, Torben & Madsen, H. T., 2004, In: Journal of Pharmacokinetics and Pharmacodynamics. 31, 5, p. 401-17 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Handlingsplan om diabetes

    Pedersen, Oluf Borbye, 2004, In: Ugeskrift for Laeger. 166, 12, p. 1099

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population

    Lauenborg, J., Hansen, Torben, Jensen, D. M., drb459, drb459, Mølsted-Pedersen, L., Hornnes, P., Locht, H., Pedersen, Oluf Borbye & Damm, Peter, 2004, In: Diabetes Care. 27, 5, p. 1194-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53 Suppl 3, p. S39-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?

    Saudek, F., Pruhová, S., Boucek, P., Lebl, J., Adamec, M., Ek, J., Pedersen, Oluf Borbye & Hansen, Torben, 2004, In: Transplantation. 77, 8, p. 1298-301 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity

    Echwald, S. M., Andersen, K. L., Sørensen, Thorkild I.A., Larsen, L. H., Andersen, T., Tonooka, N., Tomura, H., Takeda, J. & Pedersen, Oluf Borbye, 2004, In: Human Mutation. 24, 5, p. 381-387 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria

    Gaede, P., Tarnow, L., Vedel, P., Parving, H. & Pedersen, Oluf Borbye, 2004, In: Nephrology, Dialysis, Transplantation. 19, 11, p. 2784-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Annals of Medicine. 36, 5, p. 355-66 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites

    Hamid, Y. H., Urhammer, S. A., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53, 12, p. 3342-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2003
  39. Published

    A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians

    Muller, Y. L., Bogardus, C., Pedersen, Oluf Borbye & Baier, L., 2003, In: Diabetes. 52, 3, p. 895-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity

    Frayling, T. M., Lindgren, C. M., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 others, Cognet, I., Hansen, Torben, Pedersen, Oluf Borbye, Ellard, S., Tuomi, T., Groop, L. C., Froguel, P., Hattersley, A. T. & Vaxillaire, M., 2003, In: Diabetes. 52, 3, p. 872-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects

    Nielsen, E. D., Hansen, L., Echwald, S. M., Drivsholm, Thomas, Borch-Johnsen, K., Ekstrøm, C. T., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Pharmacogenetics and Genomics. 13, 7, p. 417-23 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Impact of low-dose acetylsalicylic acid on kidney function in type 2 diabetic patients with elevated urinary albumin excretion rate

    Gaede, P., Hansen, H. P., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Nephrology, Dialysis, Transplantation. 18, 3, p. 539-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?

    Poulsen, P., Andersen, G., Fenger, M., Hansen, Torben, Echwald, S. M., Vølund, A., Beck-Nielsen, H., Pedersen, Oluf Borbye & Vaag, Allan, 2003, In: Diabetes. 52, 1, p. 194-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Insulin resistance and maximal oxygen uptake

    Seibaek, M., drb459, drb459, Burchardt, H., Sloth, C., Torp-Pedersen, Christian, Nielsen, S. L., Hildebrandt, P. & Pedersen, Oluf Borbye, 2003, In: Clinical Cardiology. 26, 11, p. 515-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes: the Steno-2 study

    Pedersen, Oluf Borbye & Gaede, P., 2003, In: Metabolism. 52, 8 Suppl 1, p. 19-23 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Leptin and bone mineral density: a cross-sectional study in obese and nonobese men

    Morberg, C. M., Tetens, Inge , Black, E., Toubro, S., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Astrup, A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 12, p. 5795-5800 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes

    Gaede, P., Vedel, P., Larsen, N., Jensen, G. V. H., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Briefings from the New England Journal of Medicine. 348, 5, p. 383-93 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Steno-2-studiet: intensiv multifaktoriel behandling reducerer forekomsten af kardiovaskulaer sygdom hos patienter med type 2-diabetes

    Gaede, P. H., Jepsen, P. V., Larsen, J. N. B., Jensen, G. V., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Ugeskrift for Laeger. 165, 26, p. 2658-61 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

    Nielsen, E. D., Hansen, L., Carstensen, Bendix, Echwald, S. M., Drivsholm, Thomas, Glümer, C., Thorsteinsson, B., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Diabetes. 52, 2, p. 573-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2002
  51. Published

    Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

    Almind, K., Delahaye, L., Hansen, Torben, Van Obberghen, E., Pedersen, Oluf Borbye & Kahn, C. R., 19 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2124-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Fat mass measured by DXA varies with scan velocity

    Black, E., Petersen, L., Kreutzer, M., Toubro, S., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Astrup, A., 2002, In: Obesity. 10, 2, p. 69-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function

    Hansen, S. K., Párrizas, M., Jensen, M. L., Pruhova, S., Ek, J., Boj, S. F., Johansen, A., Maestro, M. A., Rivera, F., Eiberg, Hans Rudolf Lytchoff, Andel, M., Lebl, J., Pedersen, Oluf Borbye, Ferrer, J. & Hansen, Torben, 2002, In: Journal of Clinical Investigation. 110, 6, p. 827-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Jagten på de genetiske determinanter for de formodede polygene former for type 2-diabetes. Status og perspektivering

    Pedersen, Oluf Borbye, Hansen, Torben, Hansen, L., Echwald, S. M. & Urhammer, S. A., 2002, In: Ugeskrift for Laeger. 164, 16, p. 2163-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome

    Buhl, E. S., Jessen, N., Pold, R., Ledet, T., Flyvbjerg, A., Pedersen, Steen, Pedersen, Oluf Borbye, Schmitz, O. & Lund, S., 2002, In: Diabetes. 51, 7, p. 2199-206 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Maturity-onset diabetes of the young--MODY. Molekylaergenetiske, patofysiologiske og kliniske karakteristika

    Hansen, Torben, Urhammer, S. A. & Pedersen, Oluf Borbye, 2002, In: Ugeskrift for Laeger. 164, 15, p. 2017-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients

    Jacobsen, P., Grarup, Niels, Tarnow, L., Parving, H. & Pedersen, Oluf Borbye, 2002, In: Nephrology, Dialysis, Transplantation. 17, 8, p. 1408-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians

    Rasmussen, S. K., Urhammer, S. A., Berglund, L. E., Jensen, J. N., Hansen, L., Echwald, S. M., Borch-Johnsen, K., Horikawa, Y., Mashima, H., Lithell, H., Cox, N. J., Hansen, Torben, Bell, G. I. & Pedersen, Oluf Borbye, 2002, In: Diabetes. 51, 12, p. 3561-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2001
  60. Published

    Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism

    drb459, drb459, Lund, S., Pedersen, Oluf Borbye & drb459, drb459, Nov 2001, In: Journal of Internal Medicine. 250, 5, p. 406-14 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Serum leptin levels in pregnant women with type 1 diabetes mellitus

    Lauszus, F., Schmitz, O., drb459, drb459, Klebe, J. G., Pedersen, Oluf Borbye & drb459, drb459, Jul 2001, In: Acta Obstetricia et Gynecologica Scandinavica. 80, 7, p. 596-601 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus

    Hansen, L., Jensen, J. N., Ekstrøm, Claus Thorn, drb459, drb459, Hansen, Teis Schjals, Pedersen, Oluf Borbye & drb459, drb459, Feb 2001, In: Diabetologia. 44, 2, p. 237-240 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    A prevalent polymorphism in the putative promotor of the UCP3 gene and its relationship to body mass index in the Danish population

    Dalgaard, L. T., Sørensen, Thorkild I.A., Drivsholm, T. B., Borch-Johnsen, K., Andersen, T., Hansen, T. & Pedersen, Oluf Borbye, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, p. 1398-1402

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

    Buemann, B., Schierning, B., Toubro, S., Bibby, B. M., Sørensen, Thorkild I.A., Dalgaard, L., Pedersen, Oluf Borbye & Astrup, A., 2001, In: International Journal of Obesity. 25, p. 467-471 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2000
  66. Published

    Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus

    Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians

    Rasmussen, S. K., Urhammer, Søren Asger, Pizzuti, A., Echwald, S. M., Ekstrøm, Claus Thorn, Hansen, L., Hansen, Torben, Borch-Johnsen, K., Frittitta, L., Trischitta, V. & Pedersen, Oluf Borbye, 2000, In: Diabetes. 49, 9, p. 1608-1611 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. 1999
  69. Published

    Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity

    Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Implications of compound heterozygous insulin receptor mutations in congenital muscle fibre type disproportion myopathy for the receptor kinase activation

    Klein, H. H., Müller, R., drb459, drb459 & Pedersen, Oluf Borbye, Feb 1999, In: Diabetologia. 42, 2, p. 245-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published
  72. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    Vorwerk, P., Christoffersen, C. T., Müller, J., drb459, drb459, Pedersen, Oluf Borbye, De Meyts, P. & drb459, drb459, 1999, In: Hormone Research. 52, 5, p. 211-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Intermediate Expansions of a GAA Repeat in the Frataxin Gene are not associated with Type 2 Diabetes or Altered Glucose-Induced ¿-cell function in Danish Caucasians

    Dalgaard, L. T., Hansen, T., Urhammer, S. A., Clausen, J. O., Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1999, In: Diabetes. 48, p. 914-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. 1998
  75. Published
  76. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients

    Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. 1997
  78. Published

    Expression of protein-tyrosine phosphatases in the major insulin target tissues

    Norris, K., Norris, F., Kono, D. H., drb459, drb459, Pedersen, Oluf Borbye, Theofilopoulos, A. N. & Møller, N. P., 6 Oct 1997, In: FEBS Letters. 415, 3, p. 243-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM

    Hansen, L., Arden, K. C., Rasmussen, S. B., Viars, C. S., drb459, drb459, Hansen, Teis Schjals, Møller, A. M., Woodgett, J. R. & Pedersen, Oluf Borbye, Aug 1997, In: Diabetologia. 40, 8, p. 940-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus

    Vestergaard, H., Rossen, M., Urhammer, S. A., Müller, J. & Pedersen, Oluf Borbye, May 1997, In: European Journal of Endocrinology. 136, 5, p. 475-82 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index

    Hansen, Torben, Andersen, C. B., Echwald, S. M., Urhammer, S. A., Clausen, J. O., drb459, drb459, Owens, D., Hansen, L. & Pedersen, Oluf Borbye, Mar 1997, In: Diabetes. 46, 3, p. 494-501 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. 1996
  83. Published

    Studies of insulin resistance in congenital generalized lipodystrophy

    Søvik, O., drb459, drb459, Trygstad, O. & Pedersen, Oluf Borbye, Jun 1996, In: Acta Paediatrica. Supplement. 413, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Impaired insulin-stimulated nonoxidative glucose metabolism in glucose-tolerant women with previous gestational diabetes

    Damm, Peter, drb459, drb459, Kühl, C. E. & Pedersen, Oluf Borbye, Feb 1996, In: American Journal of Obstetrics and Gynecology. 174, 2, p. 722-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. 1995
  86. Published

    Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM

    Klein, H. H., drb459, drb459, Kotzke, G. & Pedersen, Oluf Borbye, Nov 1995, In: Diabetes. 44, 11, p. 1310-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control

    drb459, drb459, Lund, S., Bjørbaek, C. & Pedersen, Oluf Borbye, Oct 1995, In: Diabetologia. 38, 10, p. 1230-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

    Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study

    drb459, drb459, Weinreb, J. E., Rosen, A. S., Bjørbaek, C., Hansen, L., Pedersen, Oluf Borbye & Kahn, B. B., Jan 1995, In: The Journal of clinical endocrinology and metabolism. 80, 1, p. 270-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy

    drb459, drb459, Klein, H. H., Hansen, T., Müller, J., Skovby, F., Bjørbaek, C., Røder, M. E. & Pedersen, Oluf Borbye, 1995, In: The Journal of Clinical Investigation. 95, 4, p. 1925-1932 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. 1994
  92. Published

    Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM

    Chen, Y. H., Hansen, L., Chen, M., Bjørbaek, C., drb459, drb459, Hansen, Teis Schjals, Cohen, P., Pedersen, Oluf Borbye & drb459, drb459, Oct 1994, In: Diabetes. 43, 10, p. 1234-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM

    Bjørbaek, C., Echwald, S. M., Hubricht, P., drb459, drb459, Hansen, Torben, Zierath, Juleen R & Pedersen, Oluf Borbye, Aug 1994, In: Diabetes. 43, 8, p. 976-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment

    drb459, drb459, Andersen, P. H., Lund, S., Vedel, P. & Pedersen, Oluf Borbye, Jan 1994, In: Diabetologia. 37, 1, p. 82-90 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. 1993
  96. Published

    Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus

    Hansen, Torben, Bjørbaek, C., drb459, drb459, Grønskov, K., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1993, In: The Journal of clinical endocrinology and metabolism. 77, 6, p. 1500-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

    Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    The effect of intensive insulin therapy on the insulin-regulatable glucose transporter (GLUT4) expression in skeletal muscle in type 1 diabetes

    Andersen, P. H., drb459, drb459, Lund, S., Vedel, P., Junker, S., Kahn, B. B. & Pedersen, Oluf Borbye, Oct 1993, In: Diabetic Medicine. 10, 8, p. 699-706 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. 1991
  100. Published

    Impaired expression of glycogen synthase mRNA in skeletal muscle of NIDDM patients

    drb459, drb459, Bjørbaek, C., Andersen, P. H., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1991, In: Diabetes. 40, 12, p. 1740-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Effects of hyperinsulinemia and hyperglycemia on insulin receptor function and glycogen synthase activation in skeletal muscle of normal man

    Bak, J. F., Møller, N., Schmitz, O., Richter, Erik A. & Pedersen, Oluf Borbye, 1991, In: Metabolism. 40, 8, p. 830-835 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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