Morten Frödin

Morten Frödin

Associate Professor

Member of:


    1. 1994
    2. Published

      Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells.

      Frödin, Morten, Peraldi, P. & Van Obberghen, E., 1994, In: Journal of Biological Chemistry. 269, 8, p. 6207-14 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Insulin-like growth factors act synergistically with basic fibroblast growth factor and nerve growth factor to promote chromaffin cell proliferation.

      Frödin, Morten & Gammeltoft, S., 1994, In: Proceedings of the National Academy of Science of the United States of America. 91, 5, p. 1771-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 1995
    5. Published

      Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.

      Frödin, Morten, Sekine, N., Roche, E., Filloux, C., Prentki, M., Wollheim, C. B. & Van Obberghen, E., 1995, In: Journal of Biological Chemistry. 270, 14, p. 7882-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Neuronal localization of pituitary adenylate cyclase-activating polypeptide 38 in the adrenal medulla and growth-inhibitory effect on chromaffin cells.

      Frödin, Morten, Hannibal, J., Wulff, B. S., Gammeltoft, S. & Fahrenkrug, J., 1995, In: Neuroscience. 65, 2, p. 599-608 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Regulation of the MAP kinase cascade in PC12 cells: B-Raf activates MEK-1 (MAP kinase or ERK kinase) and is inhibited by cAMP.

      Peraldi, P., Frödin, Morten, Barnier, J. V., Calleja, V., Scimeca, J. C., Filloux, C., Calothy, G. & Van Obberghen, E., 1995, In: FEBS Letters. 357, 3, p. 290-6 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 1999
    9. Published

      90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

      Jensen, C. A. J., Buch, M. B., Krag, T. O., Hemmings, B. A., Gammeltoft, S. & Frödin, Morten, 1999, In: Journal of Biological Chemistry. 274, 38, p. 27168-76 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

      Frödin, Morten & Gammeltoft, S., 1999, In: Molecular and Cellular Endocrinology. 151, 1-2, p. 65-77 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Transforming growth factor-beta, but not ciliary neurotrophic factor, inhibits DNA synthesis of adrenal medullary cells in vitro.

      Wolf, N., Krohn, K., Bieger, S., Frödin, Morten, Gammeltoft, S., Krieglstein, K. & Unsicker, K., 1999, In: Neuroscience. 90, 2, p. 629-41 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2000
    13. Published

      A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

      Frödin, Morten, Jensen, C. A. J., Merienne, K. & Gammeltoft, S., 2000, In: EMBO Journal. 19, 12, p. 2924-34 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. 2001
    15. Published

      Identification and characterization of an inner ear-expressed human melanoma inhibitory activity (MIA)-like gene (MIAL) with a frequent polymorphism that abolishes translation.

      Rendtorff, N. D., Frödin, Morten, Attié-Bitach, T., Vekemans, M. & Tommerup, Niels, 2001, In: Genomics. 71, 1, p. 40-52 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2002
    17. Published

      A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.

      Frödin, Morten, Antal, T. L., Dümmler, B. A., Jensen, C. J., Deak, M., Gammeltoft, S. & Biondi, R. M., 2002, In: EMBO Journal. 21, 20, p. 5396-407 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2003
    19. Published

      ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth.

      Zhao, J., Yuan, X., Frödin, Morten & Grummt, I., 2003, In: Molecular Cell. 11, 2, p. 405-13 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.

      Perdiguero, E., Pillaire, M., Bodart, J., Hennersdorf, F., Frödin, Morten, Duesbery, N. S., Alonso, G. & Nebreda, A. R., 2003, In: EMBO Journal. 22, 21, p. 5746-56 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2004
    22. Published

      Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells.

      Silverman, E., Frödin, Morten, Gammeltoft, S. & Maller, J. L., 2004, In: Molecular and Cellular Biology. 24, 24, p. 10573-83 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2005
    24. Published

      Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/RSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations

      Rendtorff, N. D., Bjerregaard, B., Frödin, Morten, Kjaergaard, S., Hove, H., Skovby, F., Brøndum-Nielsen, T. D. T. S. G. K. & Schwartz, M., 2005, In: Human Mutation. 26, 4, p. 374-383 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types.

      Dümmler, B. A., Hauge, C., Silber, J., Yntema, H. G., Kruse, L. S., Kofoed, B., Hemmings, B. A., Alessi, D. R. & Frödin, Morten, 2005, In: Journal of Biological Chemistry. 280, 14, p. 13304-14 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein.

      Artus, J., Vandormael-Pournin, S., Frödin, Morten, Nacerddine, K., Babinet, C. & Cohen-Tannoudji, M., 2005, In: Molecular and Cellular Biology. 25, 14, p. 6289-302 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. 2006
    28. Published

      RSK and MSK in MAP kinase signalling.

      Hauge, C. & Frödin, Morten, 2006, In: Journal of Cell Science. 119, Pt 15, p. 3021-3 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2007
    30. Published

      A RSK kinase inhibitor reporting its selectivity in vivo.

      Frödin, Morten, 2007, In: Nature Chemical Biology. 3, 3, p. 138-9 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.

      Sapkota, G. P., Cummings, L., Newell, F. S., Armstrong, C., Bain, J., Frödin, Morten, Grauert, M., Hoffmann, M., Schnapp, G., Steegmaier, M., Cohen, P. & Alessi, D. R., 2007, In: Biochemical Journal. 401, 1, p. 29-38 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Heregulin-induced epigenetic regulation of the utrophin-A promoter.

      Basu, U., Gyrd-Hansen, Mads, Baby, S. M., Lozynska, O., Krag, T. O. B., Jensen, C. J., Frödin, Morten & Khurana, T. S., 2007, In: FEBS Letters. 581, 22, p. 4153-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation.

      Hauge, C., Antal, T. L., Hirschberg, D., Doehn, U., Thorup, K., Idrissova, L., Hansen, K., Jensen, O. N., Jørgensen, T. J., Biondi, R. M. & Frödin, Morten, 2007, In: EMBO Journal. 26, 9, p. 2251-61 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. 2009
    35. Published

      RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells

      Doehn, U., Hauge, C., Frank, S. R., Jensen, C. A. J., Duda, K., Nielsen, J. V., Cohen, M. S., Johansen, Jens Vilstrup, Winther, B. R., Lund, L. R., Winther, Ole, Taunton, J., Hansen, S. H. & Frödin, Morten, 2009, In: Molecular Cell. 35, 4, p. 511-22 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1)

      Dettori, R., Sonzogni, S., Meyer, L., Lopez-Garcia, L. A., Morrice, N. A., Zeuzem, S., Engel, M., Piiper, A., Neimanis, S., Frödin, Morten & Biondi, R. M., 2009, In: Journal of Biological Chemistry. 284, 44, p. 30318-27 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. 2011
    38. Published

      High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

      Chen, F., Pruett-Miller, S. M., Huang, Y., Gjoka, M., Duda, K., Taunton, J., Collingwood, T. N., Frödin, Morten & Davis, G. D., Sep 2011, In: Nature Methods. 8, 9, p. 753-5 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 9576