Mikkel-Ole Skjødt

Mikkel-Ole Skjødt

Associate Professor

ORCID: 0000-0003-1306-6482

Publication year:
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  1. 2023
  2. Published

    Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody

    Cyranka, L., Mariegaard, I., Skjødt, Mikkel-Ole, Bayarri-Olmos, R., Mollnes, T. E., Garred, Peter & Rosbjerg, A., 2023, In: Journal of Innate Immunity. 15, 1, p. 836-849

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19

    Götz, M. P., Skjødt, Mikkel-Ole, Bayarri-Olmos, R., Hansen, Cecilie Bo, Pérez-Alós, L., Jarlhelt, I., Benfield, Thomas, Rosbjerg, Anne & Garred, Peter, 2023, In: Journal of Innate Immunity. 15, 1, p. 122–135

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2021
  5. Published

    Antibody-dependent neutralizing capacity of the SARS-CoV-2 vaccine BNT162b2 with and without previous COVID-19 priming

    Hansen, Cecilie Bo, Jarlhelt, I., Hasselbalch, R. B., Hamm, S. R., Fogh, K., Pries-Heje, M. M., Møller, D. L., Heftdal, Line Dam, Pérez-Alós, L., Sørensen, E., Larsen, M. A. H., Skjødt, Mikkel-Ole, Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Bayarri-Olmos, R., Hilsted, Linda, Bundgård, Henning, Nielsen, Susanne Dam, Iversen, Kasper & Garred, Peter, 2021, In: Journal of Internal Medicine. 290, 6, p. 1272-1274

    Research output: Contribution to journal › Letter › Research › peer-review

  6. Published

    Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

    Bayarri-Olmos, R., Jarlhelt, I., Johnsen, L. B., Hansen, Cecilie Bo, Helgstrand, C., Rose Bjelke, J., Matthiesen, F., Nielsen, Susanne Dam, Iversen, Kasper, Ostrowski, Sisse Rye, Bundgård, Henning, Frikke-Schmidt, Ruth, Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: Frontiers in Immunology. 12, 757197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    MASP-1 and MASP-3 bind directly to aspergillus fumigatus and promote complement activation and phagocytosis

    Rosbjerg, Anne, Würzner, R., Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: Journal of Innate Immunity. 13, 4, p. 211-224 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Reply to Lassaunière: On the functional characterization of the Y453F RBD variant found in cluster 5 SARS-CoV-2

    Bayarri-Olmos, R., Johnsen, L. B., Rosbjerg, Anne, Helgstrand, C., Bak-Thomsen, T., Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: Journal of Biological Chemistry. 297, 5, 101241.

    Research output: Contribution to journal › Letter › Research

  9. Published

    SARS-CoV-2 Antibodies Mediate Complement and Cellular Driven Inflammation

    Jarlhelt, I., Nielsen, S. K., Jahn, C. X. H., Hansen, Cecilie Bo, Pérez-Alós, L., Rosbjerg, A., Bayarri-Olmos, R., Skjødt, Mikkel-Ole & Garred, Peter, 2021, In: Frontiers in Immunology. 12, 11 p., 767981.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    SARS-CoV-2 antibody responses are correlated to disease severity in COVID-19 convalescent individuals

    Hansen, Cecilie Bo, Jarlhelt, I., Pérez-Alós, L., Landsy, L. H., Loftager, M., Rosbjerg, Anne, Helgstrand, C., Bjelke, J. R., Egebjerg, T., Jardine, J. G., Jørgensen, C. S., Iversen, Kasper, Bayarri-Olmos, R., Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: Journal of Immunology. 206, 1, p. 109-117 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    SARS-CoV-2 neutralizing antibody responses towards full-length spike protein and the receptor-binding domain

    Bayarri-Olmos, R., Idorn, M., Rosbjerg, A., Pérez-Alós, L., Hansen, Cecilie Bo, Johnsen, L. B., Helgstrand, C., Zosel, F., Bjelke, J. R., Öberg, F. K., Søgaard, M., Paludan, S. R., Bak-Thomsen, T., Jardine, J. G., Skjødt, Mikkel-Ole & Garred, Peter, 2021, In: Journal of Immunology. 207, 3, p. 878-887 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The SARS-CoV-2 Y453F mink variant displays a pronounced increase in ACE-2 affinity but does not challenge antibody neutralization

    Bayarri-Olmos, R., Rosbjerg, Anne, Johnsen, L. B., Helgstrand, C., Bak-Thomsen, T., Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: Journal of Biological Chemistry. 296, A13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice

    Bayarri-Olmos, R., Johnsen, L. B., Idorn, M., Reinert, L. S., Rosbjerg, Anne, Vang, S., Hansen, Cecilie Bo, Helgstrand, C., Bjelke, J. R., Bak-Thomsen, T., Paludan, S. R., Garred, Peter & Skjødt, Mikkel-Ole, 2021, In: eLife. 10, 14 p., e70002.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2019
  15. Published

    Combining MAP-1:CD35 or MAP-1:CD55 fusion proteins with pattern-recognition molecules as novel targeted modulators of the complement cascade

    Pérez-Alós, L., Bayarri-Olmos, R., Skjødt, Mikkel-Ole & Garred, Peter, 2019, In: F A S E B Journal. 33, 11, p. 12723-12734 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    THE PATTERN RECOGNITION MOLECULES MBL AND C1Q DETACH FROM THEIR PATHOGEN LIGANDS UPON COMPLEMENT ACTIVATION

    Rosbjerg, Anne, Garred, Peter & Skjødt, Mikkel-Ole, 2019, In: Molecular Immunology. 114, p. 490-490

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. 2018
  18. Published

    Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities

    Hertz, C. E., Bayarri-Olmos, R., Kirketerp-Møller, N., van Putten, S., Pilely, K., Skjødt, Mikkel-Ole & Garred, Peter, 2018, In: Frontiers in Immunology. 9, 13 p., 1945.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1)

    Bayarri-Olmos, R., Kirketerp-Moller, N., Pérez-Alós, L., Skjodt, K., Skjødt, Mikkel-Ole & Garred, Peter, 2018, In: Frontiers in Immunology. 9, 14 p., 2238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2017
  21. Published

    C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques

    Pilely, K., Fumagalli, S., Rosbjerg, A., Genster, N., Skjødt, Mikkel-Ole, Perego, C., Ferrante, A. M. R., De Simoni, M. & Garred, Peter, 2017, In: Frontiers in Immunology. 8, 14 p., 1040.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2016

  23. Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injury

    Ozaki, M., Kang, Y., Tan, Y. S., Pavlov, V. I., Liu, B., Boyle, D. C., Kushak, R. I., Skjødt, Mikkel-Ole, Grabowski, E. F., Taira, Y. & Stahl, G. L., Oct 2016, In: Kidney International. 90, 4, p. 774-782 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation

    Kozarcanin, H., Lood, C., Fog, L. M., Sandholm, K., Hamad, O. A., Bengtsson, A. A., Skjødt, Mikkel-Ole, Huber-Lang, M., Garred, Peter, Ekdahl, K. N. & Nilsson, B., Mar 2016, In: Journal of Thrombosis and Haemostasis. 14, 3, p. 531-545 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2015
  26. Published

    Genetically engineered fusion of MAP-1 and factor H domains 1-5 generates a potent dual upstream inhibitor of both the lectin and alternative complement pathways

    Nordmaj, Mie Anemone, Munthe-Fog, L., Hein, E., Skjødt, Mikkel-Ole & Garred, Peter, Dec 2015, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29, 12, p. 4945-55 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema

    Hansen, C. B., Csuka, D., Munthe-Fog, L., Varga, L., Farkas, H., Hansen, K. M., Koch, C., Skjødt, K., Garred, Peter & Skjødt, Mikkel-Ole, 15 Oct 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 8, p. 3596-604 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Soluble Collectin-12 (CL-12) Is a Pattern Recognition Molecule Initiating Complement Activation via the Alternative Pathway

    Ma, Y. J., Hein, E., Munthe-Fog, L., Skjødt, Mikkel-Ole, Bayarri-Olmos, R., Romani, L. & Garred, Peter, 1 Oct 2015, In: Journal of immunology (Baltimore, Md. : 1950). 195, 7, p. 3365-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Novel CFI mutation in a patient with leukocytoclastic vasculitis may redefine the clinical spectrum of Complement Factor I deficiency

    Bay, J. T., Katzenstein, T. L., Kofoed, K., Patel, D., Skjødt, Mikkel-Ole, Garred, Peter & Schejbel, L., Oct 2015, In: Clinical Immunology. 160, 2, p. 315-8 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  30. Published

    Pentraxin-3 level at admission is a strong predictor of short-term mortality in a community-based hospital setting

    Bastrup-Birk, S., Munthe-Fog, L., Skjødt, Mikkel-Ole, Ma, Y. J., Nielsen, H., Køber, Lars Valeur, Nielsen, Olav Wendelboe, Iversen, Kasper & Garred, Peter, May 2015, In: Journal of Internal Medicine. 277, 5, p. 562-572 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Ficolins and the lectin pathway of complement in patients with systemic lupus erythematosus

    Hein, E., Nielsen, L. A., Nielsen, C. T., Munthe-Fog, L., Skjødt, Mikkel-Ole, Jacobsen, Søren & Garred, Peter, Feb 2015, In: Molecular Immunology. 63, 2, p. 209-214 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2014
  33. Published

    A specific assay for quantification of human C4c by use of an anti-C4c monoclonal antibody

    Pilely, K., Skjødt, Mikkel-Ole, Nielsen, C., Andersen, T. E., Louise Aabom, A., Vitved, L., Koch, C., Skjødt, K. & Palarasah, Y., Mar 2014, In: Journal of Immunological Methods. 405, p. 87-96 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 45779926