Michal Tomasz Marzec
Guest researcher
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
In silico approach to predict pancreatic β-cells classically secreted proteins
Pinheiro-Machado, E., Sandberg, T. O. M., Pihl, Celina, Hägglund, Per Mårten & Marzec, Michal Tomasz, 1 Jan 2020, In: Bioscience Reports. 40, 2, 13 p., BSR20193708.Research output: Contribution to journal › Journal article › Research › peer-review
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A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production
Marzec, Michal Tomasz, Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, Oluf Borbye, Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., May 2016, In: Endocrinology. 157, 5, p. 1914-1928 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Activation of Mammalian Target of Rapamycin in Transformed B Lymphocytes Is Nutrient Dependent but Independent of Akt, Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase, Insulin Growth Factor-I, and Serum.
Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, Michal Tomasz, Robertson, E. S., Slupianek, A. & Wasik, M. A., 2005, In: Cancer Research. 65, 17, p. 7800-7808 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Activation of mTORC1 signaling pathway in AIDS-related lymphomas.
El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Robertson, E. & Wasik, M. A., 2009, In: American Journal of Pathology. 175, 2, p. 817-824 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches
Wasik, M. A., Zhang, Q., Marzec, Michal Tomasz, Kasprzycka, M., Wang, H. Y. & Liu, X., 2009, In: Seminars in Oncology. 36, 2 Suppl 1, p. S27-35Research output: Contribution to journal › Journal article › Research › peer-review
Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.
El-Salem, M., Raghunath, P. N., Marzec, Michal Tomasz, Wlodarski, P., Tsai, D., Hsi, E. & Wasik, M. A., 2007, In: Laboratory Investigation. 87, 1, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma.
Lee, S., Marzec, Michal Tomasz, Liu, X., Wehrli, S., Kantekure, K., Ragunath, P. N., Nelson, D. S., Delikatny, E. J., Glickson, J. D. & Wasik, M. A., 2013, In: NMR in Biomedicine. 26, 1, p. 106-114 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells
Khilji, Muhammad Saad, Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., Buus, Søren, Nielsen, M., Klusek, J., Mandrup-Poulsen, Thomas, Pandey, K., Purcell, A. W. & Marzec, Michal Tomasz, 2022, In: Biomedicines. 10, 4, 814.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells
Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling
Ghiasi, S. M., Dahlby, T., Hede Andersen, C., Haataja, L., Petersen, S., Omar-Hmeadi, M., Yang, M., Pihl, Celina, Bresson, S. E., Khilji, Muhammad Saad, Klindt, K., Cheta, O., Perone, M. J., Tyrberg, B., Prats, C., Barg, S., Tengholm, A., Arvan, P., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, Apr 2019, In: Diabetes. 68, 4, p. 747-760 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in beta-Cells
Dahlby, T., Simon, C., Backe, M. B., Dahllof, M. S., Holson, E., Wagner, B. K., Boni-Schnetzler, M., Marzec, Michal Tomasz, Lundh, M. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences. 21, 21, 18 p., 8016.Research output: Contribution to journal › Journal article › Research › peer-review
Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes.
Kasprzycka, M., Majewski, M., Wang, Z., Ptasznik, A., Wysocka, M., Zhang, Q., Marzec, Michal Tomasz, Gimotty, P., Crompton, M. R. & Wasik, M. A., 2006, In: American Journal of Pathology. 168, 5, p. 1631-1641 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of FOXP3(+) regulatory T-cell phenotype in neoplastic and reactive cells in early mycosis fungoides
Witkiewicz, A. K., Potoczek, M., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M., Jan 2008, In: Modern Pathology. 21, p. 103A-103AResearch output: Contribution to journal › Journal article › Research › peer-review
- Published
FK506-Binding Protein 2 Participates in Proinsulin Folding
Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, , 2023, In: Biomolecules. 13, 1, 20 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum
Marzec, Michal Tomasz, Eletto, D. & Argon, Y., Mar 2012, In: B B A - Reviews on Cancer. 1823, 3, p. 774-87 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production
Argon, Y., Bresson, S. E., Marzec, Michal Tomasz & Grimberg, A., 2020, In: Cells. 9, 8, 12 p., 1844.Research output: Contribution to journal › Review › Research › peer-review
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Glutathione S-Transferase P1 Genetic Variant’s Influence on the HbA1c Level in Type Two Diabetic Patients
Orlewska, K., Klusek, J., Głuszek, S., Klusek, J., Witczak, B., Wawszczak, M., Madej, Ł., Marzec, Michal Tomasz & Orlewska, E., 2023, In: International Journal of Environmental Research and Public Health. 20, 2, 9 p., 1520.Research output: Contribution to journal › Journal article › Research › peer-review
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IDF2022-0254 Glutathione S-transferase P1 genetic variants influence the HbA1c level in diabetic patients
Klusek, J., Głuszek, S., Orlewska, K., Marzec, Michal Tomasz, Wawszczak-kasza, M., Madej, Ł., Klusek, J., Witczak, B. & Orlewska, E., 2023, In: Diabetes Research and Clinical Practice. 197, Suppl. 1, 1 p., 110268.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes
Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions
Pinheiro-Machado, E., Convey, E. G. & Marzec, Michal Tomasz, 2023, In: Archives of Medical Science. 19, 4, 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Jak3 contributes to the activation of ALK and Stat3 in ALK + anaplastic large cell lymphoma. Response.
Wasik, M. A. & Marzec, Michal Tomasz, 2006, In: Laboratory Investigation. 86, 4, p. 420-421 2 p.Research output: Contribution to journal › Letter › Research
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MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity
Tyka, K., Joerns, A., Dunst, A., Tang, Y., Holgersen Bryde, Tenna, Mehmeti, I., Walentinsson, A., Marselli, L., Cnop, M., Tyrberg, B., Marzec, Michal Tomasz & Gurgul-Convey, E., 2021, In: B B A - Molecular Basis of Disease. 1867, 10, 12 p., 166199.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCPIP1 regulates insulin biosynthesis and glucose-stimulated insulin secretion: [Meeting Abstract]
Tyka, K., Brydde, T. H., Wilamowski, M., Jura, J., Marzec, Michal Tomasz & Gurgul-Convey, E., 2019, In: FEBS Open Bio. 9, S1, p. 87-87 P-01-064.Research output: Contribution to journal › Conference abstract in journal › Research
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Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming
Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 129941679
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Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells
Research output: Contribution to journal › Journal article › Research › peer-review
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119
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Glutathione S-Transferase P1 Genetic Variant’s Influence on the HbA1c Level in Type Two Diabetic Patients
Research output: Contribution to journal › Journal article › Research › peer-review
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85
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The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β
Research output: Contribution to journal › Journal article › Research › peer-review
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