Michal Tomasz Marzec

Michal Tomasz Marzec

Guest researcher

ORCID: 0000-0001-9698-6019

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  1. STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

    Zhang, Q., Wang, H. Y., Marzec, Michal Tomasz, Raghunath, P. N., Nagasawa, T. & Wasik, M. A., 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 19, p. 6948-6953 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. PU.1 activates transcription of SHP-1 gene in hematopoietic cells.

    Wlodarski, P., Zhang, Q., Liu, X., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M. A., 2007, In: Journal of Biological Chemistry. 282, 9, p. 6316-6323 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Activation of Mammalian Target of Rapamycin in Transformed B Lymphocytes Is Nutrient Dependent but Independent of Akt, Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase, Insulin Growth Factor-I, and Serum.

    Wlodarski, P., Kasprzycka, M., Liu, X., Marzec, Michal Tomasz, Robertson, E. S., Slupianek, A. & Wasik, M. A., 2005, In: Cancer Research. 65, 17, p. 7800-7808 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Expression of FOXP3(+) regulatory T-cell phenotype in neoplastic and reactive cells in early mycosis fungoides

    Witkiewicz, A. K., Potoczek, M., Kasprzycka, M., Marzec, Michal Tomasz & Wasik, M., Jan 2008, In: Modern Pathology. 21, p. 103A-103A

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Jak3 contributes to the activation of ALK and Stat3 in ALK + anaplastic large cell lymphoma. Response.

    Wasik, M. A. & Marzec, Michal Tomasz, 2006, In: Laboratory Investigation. 86, 4, p. 420-421 2 p.

    Research output: Contribution to journal › Letter › Research

  6. Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches

    Wasik, M. A., Zhang, Q., Marzec, Michal Tomasz, Kasprzycka, M., Wang, H. Y. & Liu, X., 2009, In: Seminars in Oncology. 36, 2 Suppl 1, p. S27-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Unexpected profile of sphingolipid contents in blood and bone marrow plasma collected from patients diagnosed with acute myeloid leukemia

    WAtek, M., Wollny, T., Pasiarski, M., Gozdz, S., Durnas, B., Wolak, P., Bucki, R., Marzec, Michal Tomasz, Chabowska, A. & Zendzian-Piotrowska, M., 2017, In: Lipids in Health and Disease. 16, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity

    Tyka, K., Joerns, A., Dunst, A., Tang, Y., Holgersen Bryde, Tenna, Mehmeti, I., Walentinsson, A., Marselli, L., Cnop, M., Tyrberg, B., Marzec, Michal Tomasz & Gurgul-Convey, E., 2021, In: B B A - Molecular Basis of Disease. 1867, 10, 12 p., 166199.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    MCPIP1 regulates insulin biosynthesis and glucose-stimulated insulin secretion: [Meeting Abstract]

    Tyka, K., Brydde, T. H., Wilamowski, M., Jura, J., Marzec, Michal Tomasz & Gurgul-Convey, E., 2019, In: FEBS Open Bio. 9, S1, p. 87-87 P-01-064.

    Research output: Contribution to journal › Conference abstract in journal › Research

  10. Published

    Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions

    Pinheiro-Machado, E., Convey, E. G. & Marzec, Michal Tomasz, 2023, In: Archives of Medical Science. 19, 4, 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    In silico approach to predict pancreatic β-cells classically secreted proteins

    Pinheiro-Machado, E., Sandberg, T. O. M., Pihl, Celina, Hägglund, Per Mårten & Marzec, Michal Tomasz, 1 Jan 2020, In: Bioscience Reports. 40, 2, 13 p., BSR20193708.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Peanut-shaped gold nanoparticles with shells of ceragenin csa-131 display the ability to inhibit ovarian cancer growth in vitro and in a tumor xenograft model

    Piktel, E., Oscilowska, I., Suprewicz, Ł., Depciuch, J., Marcińczyk, N., Chabielska, E., Wolak, P., Głuszek, K., Klimek, J., Zieliński, P. M., Marzec, Michal Tomasz, Savage, P. B., Parlińska-Wojtan, M. & Bucki, R., 2021, In: Cancers. 13, 21, p. 1-26 5424.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Glutathione S-Transferase P1 Genetic Variant’s Influence on the HbA1c Level in Type Two Diabetic Patients

    Orlewska, K., Klusek, J., Głuszek, S., Klusek, J., Witczak, B., Wawszczak, M., Madej, Ł., Marzec, Michal Tomasz & Orlewska, E., 2023, In: International Journal of Environmental Research and Public Health. 20, 2, 9 p., 1520.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing

    Nagasawa, T., Zhang, Q., Raghunath, P. N., Wong, H. Y., El-Salem, M., Szallasi, A., Marzec, Michal Tomasz, Gimotty, P., Rook, A. H., Vonderheid, E. C., Ødum, Niels & Wasik, M. A., 2006, In: Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis. 30, 3, p. 303-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Oncogenic kinase NPM/ALK induces expression of HIF1 alpha mRNA

    Marzec, Michal Tomasz, Liu, X., Wong, W., Yang, Y., Pasha, T., Kantekure, K., Zhang, P., Woetmann, Anders , Cheng, M., Ødum, Niels & Wasik, M. A., 2011, In: Oncogene. 30, 11, p. 1372-1378 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells

    Marzec, Michal Tomasz, Liu, X., Wysocka, M., Rook, A. H., Ødum, Niels & Wasik, M. A., 16 Sep 2011, In: PLoS ONE. 6, 9, 8 p., e24849.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Students’ supervision and introduction during the initial period in the research laboratory: does it matter?

    Marzec, Michal Tomasz, 2018, Improving University Science Teaching and Learning: Pedagogical Projects 2018. Department of Science Education, University of Copenhagen, Denmark, p. 107-114 8 p. (Improving University Science Teaching and Learning - Pedagogical Projects, Vol. 12).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  18. Published

    Differential Effects of Interleukin-2 and Interleukin-15 versus Interleukin-21 on CD4+ Cutaneous T-Cell Lymphoma Cells

    Marzec, Michal Tomasz, Halasa, K., Kasprzycka, M., Wysocka, M., Liu, X., Tobias, J. W., Baldwin, D., Zhang, Q., Ødum, Niels, Rook, A. H. & Wasik, M. A., 2008, In: Cancer Research. 68, 4, p. 1083-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming

    Marzec, Michal Tomasz, Halasa, K., Liu, X., Wang, H. Y., Cheng, M., Baldwin, D., Tobias, J. W., Schuster, S. J., Woetmann, Anders , Zhang, Q., Turner, S. D., Ødum, Niels & Wasik, M. A., 15 Dec 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 12, p. 6200-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

    Marzec, Michal Tomasz, Zhang, Q., Goradia, A., Raghunath, P. N., Liu, X., Paessler, M., Wang, H. Y., Wysocka, M., Cheng, M., Ruggeri, B. A. & Wasik, M. A., 30 Dec 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 52, p. 20852-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum

    Marzec, Michal Tomasz, Eletto, D. & Argon, Y., Mar 2012, In: B B A - Reviews on Cancer. 1823, 3, p. 774-87 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes

    Marzec, Michal Tomasz, Liu, X., Kasprzycka, M., Witkiewicz, A., Raghunath, P. N., El-Salem, M., Robertson, E., Ødum, Niels & Wasik, M. A., 2008, In: Blood. 111, 4, p. 2181-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

    Marzec, Michal Tomasz, Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, Oluf Borbye, Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., May 2016, In: Endocrinology. 157, 5, p. 1914-1928 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity

    Marzec, Michal Tomasz, Kasprzycka, M., Lai, R., Gladden, A. B., Wlodarski, P., Tomczak, E., Nowell, P., DePrimo, S. E., Sadis, S., Eck, S., Schuster, S. J., Diehl, J. A. & Wasik, M. A., 1 Sep 2006, In: Blood. 108, 5, p. 1744-1750

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

    Marzec, Michal Tomasz, Kasprzycka, M., Ptasznik, A., Wlodarski, P., Zhang, Q., Ødum, Niels & Wasik, M. A., 2005, In: Laboratory Investigation. 85, 12, p. 1544-54 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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