Michael J. Davies

Michael J. Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael J. & Puppo, A., 16 Aug 1995, In: Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael J., Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In: The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Thiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase

    Morgan, P. E., Laura, R. P., Maki, R. A., Reynolds, W. F. & Davies, Michael J., 27 Mar 2015, In: Free Radical Research. 49, 6, p. 743-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael J., Aug 2013, In: Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael J., Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Protective mechanisms against peptide and protein peroxides generated by singlet oxygen

    Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline

    Morgan, P. E., Pattison, D. I. & Davies, Michael J., 15 Jan 2012, In: Free Radical Biology & Medicine. 52, 2, p. 328-39 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael J., 2014, In: PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis

    Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael J., Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael J. & Dean, R. T., 15 Mar 1998, In: Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael J., Dean, R. T. & Fu, S., Nov 1998, In: Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael J. & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls

    Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael J., 2022, In: Redox Biology. 52, 8 p., 102299.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

    Murphy, M. P., Bayir, H., Belousov, V., Chang, C. J., Davies, K. J. A., Davies, M. J., Dick, T. P., Finkel, T., Forman, H. J., Janssen-Heininger, Y., Gems, D., Kagan, V. E., Kalyanaraman, B., Larsson, N. G., Milne, G. L., Nyström, T., Poulsen, H. E., Radi, R., Van Remmen, H., Schumacker, P. T. & 5 others, Thornalley, P. J., Toyokuni, S., Winterbourn, C. C., Yin, H. & Halliwell, B., 2022, In: Nature Metabolism. 4, 6, p. 651-662

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael J., Columb, M. O. & Stratford, N., Apr 1996, In: British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael J., Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    1,4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress

    Ng, H. H., Leo, C. H., O'Sullivan, K., Alexander, S., Davies, Michael J., Schiesser, C. H. & Parry, L. J., Mar 2017, In: Biochemical Pharmacology. 128, p. 34-45 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effect of free cysteine on the denaturation and aggregation of holo α-lactalbumin

    Nielsen, L. R., Lund, Marianne N., Davies, Michael J., Nielsen, J. H. & Nielsen, S. B., 2018, In: International Dairy Journal. 79, p. 52-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I

    Nobecourt, E., Zeng, J., Davies, Michael J., Brown, B. E., Yadav, S., Barter, P. J. & Rye, K. -., Jun 2008, In: Diabetologia. 51, 6, p. 1008-1017 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase

    Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael J., Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Analysis of protein chlorination by mass spectrometry

    Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2019, In: Redox Biology. 26, 10 p., UNSP 101236.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Analysis of extracellular matrix protein chlorination and oxidation by mass spectrometry: [Meeting Abstract]

    Nybo, T., Davies, Michael J. & Rogowska-Wrzesinska, A., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S56-S57 P-40.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  29. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., Oct 2018, In: Redox Biology. 19, p. 388-400

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function: [Meeting Abstract]

    Nybo, T., Cai, H., Chuang, Christine, Gamon, Luke Francis, Rogowska-Wrzesinska, A. & Davies, Michael J., 2018, In: Free Radical Biology & Medicine. 120, S1, p. S24-S24 P-41 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  31. Published

    Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

    Nybo, T., Dieterich, S., Gamon, Luke Francis, Chuang, Christine, Hammer, A., Hoefler, G., Malle, E., Rogowska-Wrzesinska, A. & Davies, Michael J., 2019, In: Redox Biology. 20, p. 496-513

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing

    Park, J. I., Grant, C. M., Davies, Michael J. & Dawes, I. W., 4 Sep 1998, In: The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals

    Park, J. S., Wood, P. M., Davies, Michael J., Gilbert, B. C. & Whitwood, A. C., Nov 1997, In: Free Radical Research. 27, 5, p. 447-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Protein-bound kynurenine is a photosensitizer of oxidative damage

    Parker, N. R., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses

    Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., Aug 2007, In: Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies

    Pattison, D. I., Levina, A., Davies, Michael J. & Lay, P. A., 15 Jan 2001, In: Inorganic Chemistry. 40, 2, p. 214-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael J., Levina, A., Dixon, N. E. & Lay, P. A., 2001, In: Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

    Pattison, D. I. & Davies, Michael J., 2001, In: Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 130-2 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael J., 26 Jun 2000, In: Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases

    Pattison, David & Davies, Michael J., 2006, In: Current Medicinal Chemistry. 13, 27, p. 3271-3290 20 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. The nitroxide TEMPO is an efficient scavenger of protein radicals: cellular and kinetic studies

    Pattison, D. I., Lam, M., Shinde, S. S., Anderson, R. F. & Davies, Michael J., 1 Nov 2012, In: Free Radical Biology & Medicine. 53, 9, p. 1664-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation

    Pattison, D. I. & Davies, Michael J., 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Actions of ultraviolet light on cellular structures

    Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.

    Research output: Contribution to journal › Journal article › Research

  49. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael J., 1 Aug 2002, In: Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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