Luis Ignacio Toledo Lazaro

Luis Ignacio Toledo Lazaro

Associate Professor


  1. 2022
  2. Published

    The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition

    Zonderland, Gijs, Vanzo, R., Gadi, Sampath Amitash, Martín-Doncel, E., Coscia, F., Mund, Andreas, Lerdrup, Mads, Benada, Jan, Boos, D. & Toledo Lazaro, Luis Ignacio, 2022, In: Molecular Cell. 82, 18, p. 3350-3365.e7 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2020
  4. Published

    Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

    Ercilla, A., Feu, S., Aranda, S., Llopis, A., Brynjólfsdóttir, S. H., Sørensen, Claus Storgaard, Toledo Lazaro, Luis Ignacio & Agell, N., 2020, In: Cellular and molecular life sciences : CMLS. 77, p. 735–749

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication

    Ercilla, A., Benada, Jan, Gadi, Sampath Amitash, Zonderland, Gijs, Baldi, G., Somyajit, K., Ochs, F., Costanzo, V., Lukas, Jiri & Toledo Lazaro, Luis Ignacio, 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. 2017
  7. Published

    Replication Catastrophe: When a Checkpoint Fails because of Exhaustion

    Toledo Lazaro, Luis Ignacio, Neelsen, K. J. & Lukas, Jiri, 15 Jun 2017, In: Molecular Cell. 66, 6, p. 735-749 15 p.

    Research output: Contribution to journalReviewpeer-review

  8. 2016
  9. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, Luis Ignacio, Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journalJournal articlepeer-review

  10. 2014
  11. Published

    The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage

    Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, Luis Ignacio, Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In: Nature Cell Biology. 16, 8, p. 792-803 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  12. 2013
  13. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, Luis Ignacio, Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

    Altmeyer, M., Toledo Lazaro, Luis Ignacio, Gudjónsson, Thorkell, Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 206-220

    Research output: Contribution to journalJournal articlepeer-review

  15. 2012
  16. Published

    TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, Luis Ignacio, Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

    Research output: Contribution to journalJournal articlepeer-review

ID: 38168750