Liv Eidsmo
Professor
Skin Immunology Research Center
Nørre Allé 14
2200 København N
ORCID: 0000-0001-9237-8374
The skin is a barrier that is constantly exposed to colonizing microbiota, invasive pathogens and allergens. Within the skin, immune cells constantly interact with stroma to avoid microbial invasion and tumor development. The skin immune system is also heavily implicated in common patchy inflammatory diseases such as vitiligo and psoriasis.
The Eidsmo Laboratory explores mechanisms that steer health and immunopathology in human skin. In healthy skin, the Eidsmo Laboratory has defined functionally distinct subsets of tissue resident memory T (Trm) cells based on their expression of the integrin CD49a. In diseases such as vitiligo and psoriasis, we have shown the involvement of different subsets of pathogenic Trm cells in the formation of localized disease memories in resolved skin.
We currently focus on how human Trm cells are formed and how these cells impact on their immediate environment. Ultimately, we want to normalise the Trm cell compartment in diseased skin to reach robust and long-term homeostasis.
ID: 253769599
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46
downloads
Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
23
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T cells in resolved allergic contact dermatitis steer tissue inflammation and MMP-12–driven tissue modulation
Research output: Contribution to journal › Letter › Research › peer-review
Published -
16
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Intestinal helminth infection transforms the CD4+ T cell composition of the skin
Research output: Contribution to journal › Journal article › Research › peer-review
Published