Lena Specht

Lena Specht

Clinical Professor

Member of:

  • Clinical Oncology


Publication year:
All
1 - 50 out of 333Page size: 50
  1. 2023
  2. Published

    A comparison of loco-regional relapse pattern in HPV positive vs negative oropharyngeal cancers following radiotherapy: relation to pretreatment FDG-PET and radiotherapy target volumes

    Håkansson, K., Lindegaard, A. M., Bernsdorf, M., Gothelf, A., Kristensen, C. A., Specht, Lena, Friborg, Jeppe Tang & Vogelius, Ivan R. , 2023, In: Acta Oncologica. 62, 9, p. 1028-1035 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A systematic review on clinical adaptive radiotherapy for head and neck cancer

    Lindegaard, A. M., Håkansson, K., Bernsdorf, M., Gothelf, A. B., Kristensen, C. A., Specht, Lena, Vogelius, Ivan R. & Friborg, Jeppe Tang, 2023, In: Acta oncologica (Stockholm, Sweden). 62, 11, p. 1360-1368 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Brentuximab Vedotin Plus AVD for First-Line Treatment of Early-Stage Unfavorable Hodgkin Lymphoma (BREACH): A Multicenter, Open-Label, Randomized, Phase II Trial

    Fornecker, L. M., Lazarovici, J., Aurer, I., Casasnovas, R. O., Gac, A. C., Bonnet, C., Bouabdallah, K., Feugier, P., Specht, L., Molina, L., Touati, M., Borel, C., Stamatoullas, A., Nicolas-Virelizier, E., Pascal, L., Lugtenburg, P., Di Renzo, N., Vander Borght, T., Traverse-Glehen, A., Dartigues, P. & 5 others, Hutchings, M., Versari, A., Meignan, M., Federico, M. & André, M., 2023, In: Journal of Clinical Oncology. 41, 2, p. 327-335 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Accepted/In press

    Career development: A balance of opportunities and choices

    de Jong, D., Kimby, E. & Specht, Lena, 2023, (Accepted/In press) In: Hematological Oncology. p. 1-4

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  6. Published

    Increased incidence rates of positive blood cultures shortly after chemotherapy compared to radiotherapy among individuals treated for solid malignant tumours

    Roen, A., Terrones, C., Bannister, W., Helleberg, M., Andersen, M. A., Niemann, Carsten, Daugaard, G., Specht, Lena, Mocroft, A., Reekie, J. & Lundgren, Jens, 2023, In: Infection. 51, 11 p., 147–157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Accepted/In press

    Personalised therapy in follicular lymphoma – is the dial turning?

    Linton, K. M., Specht, Lena, Pavlovsky, A., Thompson, C. A., Kimby, E., de Jong, D., Nastoupil, L. J., Cottereau, A. S., Casulo, C., Sarkozy, C. & Okosun, J., 2023, (Accepted/In press) In: Hematological Oncology. 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Prediction of Radiation-induced Lymphopenia following Exposure of the Thoracic Region and Associated Risk of Infections and Mortality

    Terrones-Campos, C., Ledergerber, B., Forbes, N., Smith, Abraham George, Petersen, Jens, Helleberg, Marie, Lundgren, Jens, Specht, Lena & Vogelius, Ivan R. , 2023, In: Clinical Oncology. 35, 7, p. e434-e444 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Radiotherapy in Cutaneous Lymphomas and Cutaneous Sarcomas

    Specht, Lena & Coyle, C., 2023, Non-melanoma Skin Cancer: Essentials for Oncologists. Rembielak, A. & Tagliaferri, L. (eds.). CRC Press, p. 305-320 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    Reappraisal of the role of radiation therapy in lymphoma treatment

    Specht, Lena, 2023, In: Hematological Oncology. 41, S1, p. 75-81 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Systemic Treatment of Cutaneous Lymphomas

    Kamstrup, M. R. & Specht, Lena, 2023, Non-melanoma Skin Cancer: Essentials for Oncologists. Rembielak, A. & Tagliaferri, L. (eds.). CRC Press, p. 355-364 10 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    The potential for local ablative therapy of oligometastases in head and neck squamous cell carcinoma: a real-world data analysis

    Kjems, J., Laursen, M. R. T., Kristensen, C. A., Gothelf, A. B., Bernsdorf, M., Specht, Lena, Berthelsen, A. K., Vogelius, Ivan R. , Persson, Gitte F. & Friborg, Jeppe Tang, 2023, In: Acta Oncologica. 62, 9, p. 1091-1095

    Research output: Contribution to journal › Letter › Research › peer-review

  13. 2022
  14. Published

    Early non-cancer mortality risk prediction after curative-intent radiotherapy or chemoradiotherapy for head and neck squamous cell carcinoma

    Jensen, K. H., Vogelius, Ivan R. , Bernsdorf, M., Gothelf, A., Kristensen, C. A., Maare, C., Andersen, E., Specht, Lena & Friborg, Jeppe Tang, Jun 2022, In: Radiotherapy and Oncology. 171, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A phase 2 trial of deep-inspiration breath hold in radiotherapy of gastric lymphomas

    Petersen, P. M., Rechner, L. A. & Specht, Lena, Apr 2022, In: Physics & imaging in radiation oncology. 22, p. 137-141 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Hyperbaric oxygen treatment of mandibular osteoradionecrosis: Combined data from the two randomized clinical trials DAHANCA-21 and NWHHT2009-1

    Forner, L. E., Dieleman, F. J., Shaw, R. J., Kanatas, A., Butterworth, C. J., Kjeller, G., Alsner, J., Overgaard, J., Hillerup, S., Hyldegaard, Ole, Arnell, P., von Buchwald, Christian, Kaanders, J. H. A. M., Smeele, L. E., Specht, Lena, Johansen, J., Witjes, M. J. H., Merkx, M. A. W. & Jansen, E. C., Jan 2022, In: Radiotherapy and Oncology. 166, p. 137-144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Baseline FDG PET/CT in free breathing versus deep inspiration breath-hold for pediatric patients with mediastinal lymphoma

    Lundgaard, A. Y., Dejanovic, D., Berthelsen, A. K., Andersen, Flemming Littrup, Rechner, L. A., Borgwardt, L., Hjalgrim, L. L., Specht, Lena & Maraldo, M. V., 2022, In: Acta Oncologica. 61, 2, p. 239-246 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cardiovascular risk factors, radiation therapy, and myocardial infarction among lymphoma survivors

    Salz, T., Zabor, E. C., Brown, Peter de Nully, Dalton, Susanne Oksbjerg, Raghunathan, N. J., Matasar, M. J., Steingart, R., Hjalgrim, Henrik, Specht, Lena, Vickers, A. J., Oeffinger, K. C. & Johansen, Christoffer, 2022, In: Acta Oncologica. 61, 9, p. 1064-1068

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Intraglandular Off-the-Shelf Allogeneic Mesenchymal Stem Cell Treatment in Patients with Radiation-Induced Xerostomia: A Safety Study (MESRIX-II)

    Lynggaard, C. D., Grønhøj, Christian, Christensen, R., Fischer-Nielsen, A., Melchiors, Jacob, Specht, Lena, Andersen, E., Mortensen, Jann, Oturai, P., Barfod, G. H., Haastrup, E. K., Møller-Hansen, M., Haack-Sørensen, M., Ekblond, A., Kastrup, J., Jensen, S. B. & von Buchwald, Christian, 2022, In: Stem Cells Translational Medicine. 11, 5, p. 478-489 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

    Lynggaard, C. D., Grønhøj, Christian, Jensen, S. B., Christensen, R., Specht, Lena, Andersen, E., Andersen, T. T., Ciochon, U. M., Rathje, G. S., Hansen, Adam Espe, Stampe, H., Fischer-Nielsen, A. & von Buchwald, Christian, 2022, In: Clinical Cancer Research. 28, 13, p. 2-2897 2896 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    PET for radiotherapy planning

    Dejanovic, D., Specht, Lena, Munk, O. L., Christensen, C. B., Berthelsen, A. K., Law, Ian & Loft, A., 2022, Nuclear Medicine and Molecular Imaging: Volume 1-4. Elsevier, Vol. 3. p. 774-792 19 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    PET/CT til radioterapi

    Specht, Lena, Berthelsen, A. K. & Jakobsen, A. L., 2022, Klinisk Nuklearmedicin. Munksgaard , p. 266-272

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  23. Published

    Patterns of relapse and long-term outcome in patients treated with a curative intent for advanced Hodgkin lymphoma

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Loft, A., Brown, Peter de Nully, Vogelius, I. R., Petersen, P. M. & Specht, Lena, 2022, In: Acta Oncologica. 61, 9, p. 1056-1063 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Response Evaluation Following Radiation Therapy With 18F-FDG PET/CT: Common Variants of Radiation-Induced Changes and Potential Pitfalls

    Dejanovic, D., Specht, Lena, Czyzewska, D., Kiil Berthelsen, A. & Loft, A., 2022, In: Seminars in Nuclear Medicine. 52, 6, p. 681-706 26 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Risk of Bacterial, Viral, and Fungal Infections in Patients With Solid Malignant Tumors Treated With Curative Intent Radiation Therapy

    Terrones-Campos, C., Ledergerber, B., Specht, Lena, Vogelius, Ivan R. , Helleberg, M. & Lundgren, Jens, 2022, In: Advances in Radiation Oncology. 7, 6, 16 p., 100950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    RootPainter3D: Interactive-machine-learning enables rapid and accurate contouring for radiotherapy

    Smith, Abraham George, Petersen, Jens, Terrones-Campos, C., Berthelsen, A. K., Forbes, N. J., Darkner, Sune, Specht, Lena & Vogelius, I. R., 2022, In: Medical Physics. 49, 1, p. 461-473

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2021
  28. Published

    Intratumor heterogeneity is biomarker specific and challenges the association with heterogeneity in multimodal functional imaging in head and neck squamous cell carcinoma

    Rasmussen, J. H., Olin, A. B., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard, Specht, Lena, Bentzen, S. M., von Buchwald, Christian, Wessel, Irene & Vogelius, Ivan R. , Jun 2021, In: European Journal of Radiology. 139, 8 p., 109668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Hematological toxicity in patients with solid malignant tumors treated with radiation – Temporal analysis, dose response and impact on survival

    Terrones-Campos, C., Ledergerber, B., Vogelius, I. R., Helleberg, M., Specht, Lena & Lundgren, Jens, May 2021, In: Radiotherapy and Oncology. 158, p. 175-183 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Iatrogenic cerebral radiation necrosis

    Hilton, C. M. H., Specht, Lena, Lund, Eva Løbner, Martens, P. C., Schmidt, G. & Krarup, L. H., 2021, In: Practical Neurology. 21, 5, p. 427-430 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Lymphoma: advances in imaging and radiotherapy – introductory editorial

    Illidge, T., Mikhaeel, N. G., Specht, Lena & Yahalom, J., 2021, In: British Journal of Radiology. 94, 1127, 2 p., 20219005.

    Research output: Contribution to journal › Editorial › Research › peer-review

  32. Published

    Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group

    Qi, S. N., Li, Y. X., Specht, Lena, Oguchi, M., Tsang, R., Ng, A., Suh, C. O., Ricardi, U., Mac Manus, M., Dabaja, B. & Yahalom, J., 2021, In: International Journal of Radiation Oncology Biology Physics. 110, 4, p. 1064-1081

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    No changes in myocardial perfusion following radiation therapy of left-sided breast cancer: A positron emission tomography study

    Rasmussen, T., Kjær, Andreas, Lassen, M. L., Pedersen, A. N., Specht, Lena, Aznar, M. C. & Hasbak, P., 2021, In: Journal of Nuclear Cardiology. 28, p. 1923–1932 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Outcome-based multiobjective optimization of lymphoma radiation therapy plans

    Modiri, A., Vogelius, Ivan R. , Ann Rechner, L., Nygård, L., Bentzen, S. M. & Specht, Lena, 2021, In: British Journal of Radiology. 94, 1127, 20210303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Prevalence of cognitive impairment and its relation to mental health in Danish lymphoma survivors

    Mariegaard, J., Wenstrup, J., Lim, K. Z. M., Bidstrup, Pernille Envold Hansen, von Heymann, A., Johansen, Christoffer, Knudsen, Gitte Moos, Law, Ian, Specht, Lena & Stenbæk, Dea Siggaard, 2021, In: Supportive Care in Cancer. 29, p. 3319–3328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Relapse localization in Danish pediatric patients with Hodgkin lymphoma

    Lundgaard, A. Y., Hjalgrim, L. L., Dejanovic, D., Berthelsen, A. K., Schomerus, E., Wendtland, P., Specht, Lena & Maraldo, M. V., 2021, In: Acta Oncologica. 60, 5, p. 658-666 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Robustness and Generalizability of Deep Learning Synthetic Computed Tomography for Positron Emission Tomography/Magnetic Resonance Imaging–Based Radiation Therapy Planning of Patients With Head and Neck Cancer

    Olin, A. B., Thomas, C., Hansen, Adam Espe, Rasmussen, J. H., Krokos, G., Urbano, T. G., Michaelidou, A., Jakoby, B., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Barrington, S. F., Andersen, Flemming Littrup & Fischer, Barbara Malene Bjerregaard, 2021, In: Advances in Radiation Oncology. 6, 6, 100762.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The risk of late effects following pediatric and adult radiotherapy regimens in Hodgkin lymphoma

    Lundgaard, A. Y., Hjalgrim, L. L., Rechner, L. A., Lundemann, M., Brodin, N. P., Joergensen, M., Specht, Lena & Maraldo, M. V., 2021, In: Strahlentherapie und Onkologie. 197, p. 711–721

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Total Body Irradiation in Haematopoietic Stem Cell Transplantation for Paediatric Acute Lymphoblastic Leukaemia: Review of the Literature and Future Directions

    Hoeben, B. A. W., Wong, J. Y. C., Fog, L. S., Losert, C., Filippi, A. R., Bentzen, S. M., Balduzzi, A. & Specht, Lena, 2021, In: Frontiers in Pediatrics. 9, 28 p., 774348.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Total tumor burden in lymphoma – an evolving strong prognostic parameter

    Meignan, M., Cottereau, A. S., Specht, Lena & Mikhaeel, N. G., 2021, In: British Journal of Radiology. 94, 1127, 9 p., 20210448.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2020
  42. Published

    Impact of p16-overexpression on overall and progression-free survival outcomes in oral cavity squamous cell carcinomas: A semi-national, population-based study

    Schneider, K., Jakobsen, K. K., Jensen, J. S., Wessel, Irene , Christensen, Anders, Specht, Lena, Lelkaitis, G., Mirian, C., Buchwald, C. V. & Grønhøj, C., 1 Dec 2020, In: Oral Oncology. 111, 5 p., 105031.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    In Reply to Scarpelli et al

    Specht, Lena, Wong, J. Y. C., Filippi, A. R., Dabaja, B. S. & Yahalom, J., 1 Dec 2020, In: International Journal of Radiation Oncology, Biology, Physics. 108, 5, p. 1396 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  44. Published

    Involved node radiation therapy in the combined modality treatment for early-stage Hodgkin lymphoma: Analysis of relapse location and long-term outcome

    Nielsen, K., Maraldo, M. V., Berthelsen, A. K., Loft, A., Brown, Peter de Nully, Vogelius, Ivan R. , Petersen, P. M. & Specht, Lena, 1 Sep 2020, In: Radiotherapy and Oncology. 150, p. 236-244 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Does multiparametric imaging with 18F-FDG-PET/MRI capture spatial variation in immunohistochemical cancer biomarkers in head and neck squamous cell carcinoma?

    Rasmussen, J. H., Olin, A., Lelkaitis, G., Hansen, Adam Espe, Andersen, Flemming Littrup, Johannesen, H. H., Kjær, Andreas, Vogelius, Ivan R. , Specht, Lena, Bentzen, S. M., Wessel, I., von Buchwald, Christian & Fischer, Barbara Malene Bjerregaard, Jul 2020, In: British Journal of Cancer. 123, 1, p. 46-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Mortality and admission to intensive care units after febrile neutropenia in patients with cancer

    Aagaard, T., Reekie, J., Jørgensen, M., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., May 2020, In: Cancer Medicine. 9, 9, p. 3033-3042 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Biological optimization for mediastinal lymphoma radiotherapy - a preliminary study

    Rechner, L. A., Modiri, A., Stick, L. B., Maraldo, M. V., Aznar, M. C., Rice, S. R., Sawant, A., Bentzen, S. M., Vogelius, Ivan R. & Specht, Lena, 27 Mar 2020, In: Acta Oncologica. 59, 8, p. 879-887 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Development and validation of a cycle-specific risk score for febrile neutropenia during chemotherapy cycles 2-6 in patients with solid cancers: The CSRFENCE score

    Aagaard, T., Reekie, J., Roen, A., Daugaard, G., Specht, Lena, Sengeløv, Henrik, Mocroft, A., Lundgren, Jens & Helleberg, M., 15 Jan 2020, In: International Journal of Cancer. 146, 2, p. 321-328 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Cardiac Lymphoma, a Challenging Extranodal Lymphoma

    Specht, Lena, 2020, In: International Journal of Radiation Oncology Biology Physics. 106, 3, 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  50. Published

    Early-stage mantle cell lymphoma—a rare entity with special characteristics and needs for treatment

    Specht, Lena & on behalf of the International Lymphoma Radiation Oncology Group (ILROG), O. B. O. T. I. L. R. O. G. (., 2020, In: Annals of Hematology. 99, 12, p. 2963-2964

    Research output: Contribution to journal › Comment/debate › Research

  51. Published

    Extranodal NK/T-cell lymphoma, nasal type, with extranasal presentation–a case report and a review of the literature

    Akbar, M., Clasen-Linde, E. & Specht, Lena, 2020, In: Acta Oncologica. p. 1-8 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  52. Published

    Feasibility of Multiparametric Positron Emission Tomography/Magnetic Resonance Imaging as a One-Stop Shop for Radiation Therapy Planning for Patients with Head and Neck Cancer

    Olin, A. B., Hansen, Adam Espe, Rasmussen, J. H., Ladefoged, C. N., Berthelsen, A. K., Håkansson, K., Vogelius, Ivan R. , Specht, Lena, Gothelf, A. B., Kjær, Andreas, Fischer, Barbara Malene Bjerregaard & Andersen, Flemming Littrup, 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 5, p. 1329-1338 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    ILROG Lymphoma Mini-Atlas Part II, Hodgkin Lymphoma

    Dabaja, B. S., Ng, A. K., Terezakis, S. A., Plastaras, J. P., Yunes, M., Wilson, L. D., Yang, J., Gunther, J. R., Specht, Lena & Yahalom, J., 2020, In: International Journal of Radiation Oncology Biology Physics. 108, 4, p. 977-978

    Research output: Contribution to journal › Editorial › Research › peer-review

  54. Published

    ILROG emergency guidelines for radiation therapy of hematological malignancies during the COVID-19 pandemic

    Yahalom, J., Dabaja, B. S., Ricardi, U., Ng, A., Mikhaeel, N. G., Vogelius, Ivan R. , Illidge, T., Qi, S., Wirth, A. & Specht, Lena, 2020, In: Blood. 135, 21, p. 1829-1832 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 917341