Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor

ORCID: 0000-0002-2165-3313

Publication year:
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1 - 61 out of 61Page size: 500
  1. 2023
  2. Published

    Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype

    Vieira, V., Lim, N., Singh, A., Leitman, E., Dsouza, R., Adland, E., Muenchhoff, M., Roider, J., Lopez, M. M., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., Frater, J. & 6 others, Walker, B. D., Ndung'U, T., Ramsuran, V., Leslie, A., Kløverpris, Henrik Nyhus & Goulder, P., 2023, In: JCI insight. 8, 3, e156049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2022

  4. A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells

    Sampson, O., Lim, N., White, J., Vieira, V., Kløverpris, Henrik Nyhus, Adland, E., Conlon, C., Skelly, D., Jones, L., Stafford, L., Jamsen, A., Barnes, E., Dunachie, S., Frater, J., Klenerman, P., Altfeld, M. & Goulder, P., 2022, In: Journal of Immunological Methods. 504, 113263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity

    Riou, C., Keeton, R., Moyo-Gwete, T., Hermanus, T., Kgagudi, P., Baguma, R., Valley-Omar, Z., Smith, M., Tegally, H., Doolabh, D., Iranzadeh, A., Tyers, L., Mutavhatsindi, H., Tincho, M. B., Benede, N., Marais, G., Chinhoyi, L. R., Mennen, M., Skelem, S., du Bruyn, E. & 31 others, Stek, C., de Oliveira, T., Williamson, C., Moore, P. L., Wilkinson, R. J., Ntusi, N. A. B., Burgers, W. A., Abrahams, F., Ayres, F., du Toit, E., Goliath, R. T., Hanekom, W., Hardie, D., Hsiao, N. Y., Kløverpris, Henrik Nyhus, Korsman, S., Lakay, F., Lambson, B., Leslie, A., Makhado, Z., Maseko, M., Mhlanga, D., Naidoo, M., Ndhlovu, Z., Ngomti, A., Oosthuysen, B., Ruzive, S., Sigal, A., Smith, T., van der Westhuizen, D. & South African Cellular Immunity Network, S. A. C. I. N., 2022, In: Science Translational Medicine. 14, 631, eabj6824.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway

    Krause, R., Snyman, J., Shi-Hsia, H., Muema, D., Karim, F., Ganga, Y., Ngoepe, A., Zungu, Y., Gazy, I., Bernstein, M., Khan, K., Mazibuko, M., Mthabela, N., Ramjit, D., Limbo, O., Jardine, J., Sok, D., Wilson, I. A., Hanekom, W., Sigal, A. & 4 others, Kløverpris, Henrik Nyhus, Ndung'u, T., Leslie, A. & COMMIT-KZN Team, C. T., 2022, In: eLife. 11, e79924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

    Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., Nguyen, S. & 6 others, de Oliveira, T., Ndung’u, T., Goulder, P., Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2022, In: Frontiers in Immunology. 13, 912038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

    Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S. H., Giandhari, J. & 32 others, Blackburn, J. M., Gosnell, B. I., Abdool Karim, S. S., Hanekom, W., Davies, M. A., Hsiao, M., Martin, D., Mlisana, K., Wibmer, C. K., Williamson, C., York, D., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Magula, N., Manickchund, N., Marakalala, M., Mazibuko, M., Moshabela, M., Mthabela, N., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Ngcobo, N., Nyamande, K., Patel, V., NGS-SA, N. & COMMIT-KZN Team, C. T., 2022, In: Nature. 602, 7898, p. 654-656 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Omicron infection enhances Delta antibody immunity in vaccinated persons

    Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., Naidoo, T. & 31 others, Sivro, A., Samsunder, N., Kharsany, A. B. M., Amoako, D., Bhiman, J. N., Manickchund, N., Abdool Karim, Q., Magula, N., Abdool Karim, S. S., Gray, G., Hanekom, W., von Gottberg, A., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Marakalala, M., Moshabela, M., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Nyamande, K., Patel, V., Smit, T., Steyn, A., Wong, E., Milo, R. & COMMIT-KZN Team, C. T., 2022, In: Nature. 607, 7918, p. 356-359 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and with Human Immunodeficiency Virus on Antiretroviral Therapy during the First South African Infection Wave

    Snyman, J., Hwa, S. H., Krause, R., Muema, D., Reddy, T., Ganga, Y., Karim, F., Leslie, A., Sigal, A., Ndung'U, T., Archary, M., Dullabh, K. J., Goulder, P., Harling, G., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Klein, N., Kloverpris, H. & 13 others, Madansein, R., Marakalala, M., Mazibuko, M., Moshabela, M., Mthabela, N., Naidoo, K., Ndhlovu, Z., Nyamande, K., Padayatchi, N., Patel, V., Smit, T., Steyn, A. & Wong, E., 2022, In: Clinical Infectious Diseases. 75, 1, p. E249-E256

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

    Kummerlowe, C., Mwakamui, S., Hughes, T. K., Mulugeta, N., Mudenda, V., Besa, E., Zyambo, K., Shay, J. E. S., Fleming, I., Vukovic, M., Doran, B. A., Aicher, T. P., Wadsworth, M. H., Bramante, J. T., Uchida, A. M., Fardoos, R., Asowata, O. E., Herbert, N., Yilmaz, Ö. H., Kløverpris, H. N. & 6 others, Garber, J. J., Ordovas-Montañes, J., Gartner, Z. J., Wallach, T., Shalek, A. K. & Kelly, P., 2022, In: Science Translational Medicine. 14, 660, eabi8633.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2021
  13. Published

    Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma

    Cele, S., Network for Genomic Surveillance in South Africa, N. F. G. S. I. S. A. & COMMIT-KZN Team, C. T., 2021, In: Nature. 593, 7857, p. 142-146 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    HIV status alters disease severity and immune cell responses in beta variant sars-COV-2 infection wave

    COMMIT-KZN Team, C. T., 2021, In: eLife. 10, e67397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection

    Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy

    Lustig, G., Cele, S., Karim, F., Derache, A., Ngoepe, A., Khan, K., Gosnell, B. I., Moosa, M. Y. S., Ntshuba, N., Marais, S., Jeena, P. M., Govender, K., Adamson, J., Kløverpris, Henrik Nyhus, Gupta, R. K., Harrichandparsad, R., Patel, V. B. & Sigal, A., 2021, In: PLOS Pathogens. 17, 9, 21 p., e1009871.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

    Ogongo, P., Tezera, L. B., Ardain, A., Nhamoyebonde, S., Ramsuran, D., Singh, A., Ng’oepe, A., Karim, F., Naidoo, T., Khan, K., Dullabh, K. J., Fehlings, M., Lee, B. H., Nardin, A., Lindestam Arlehamn, C. S., Sette, A., Behar, S. M., Steyn, A. J. C., Madansein, R., Kløverpris, H. N. & 2 others, Elkington, P. T. & Leslie, A., 2021, In: Journal of Clinical Investigation. 131, 10, e142014.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2020

  20. Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

    Attaf, M., Roider, J., Malik, A., Rius Rafael, C., Dolton, G., Predergast, A. J., Leslie, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Sewell, A. K. & Goulder, P. J., 2020, In: Frontiers in Immunology. 11, 1587.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection

    Muenchhoff, M., Chung, A. W., Roider, J., Dugast, A. S., Richardson, S., Kløverpris, Henrik Nyhus, Leslie, A., Ndung’u, T., Moore, P., Alter, G. & Gouldera, P. J. R., 2020, In: mSphere. 5, 6, p. 1-16 e00880-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

    Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung'u, T., Shalek, A. K., Goulder, P., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Cell Reports. 32, 11, 108153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection

    Magnoumba, M., Singh, A., Ogongo, P., Roider, J., Asowata, O., Fehlings, M., Karim, F., Ndung'u, T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Frontiers in Immunology. 11, 579743.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2019
  25. Published

    Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

    Muenchhoff, M., Adland, E., Roider, J., Kløverpris, Henrik Nyhus, Leslie, A., Boehm, S., Keppler, O. T., Ndung'u, T. & Goulder, P. J. R., 2019, In: The Journal of Infectious Diseases. 219, 9, p. 1407-1417 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

    Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, Henrik Nyhus, Colonna, M., Leslie, A. & Khader, S. A., 2019, In: Nature. 570, 7762, p. 528-532

    Research output: Contribution to journal › Letter › Research › peer-review

  27. Published

    Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children

    Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2019, In: Frontiers in Immunology. 10, FEB, 12 p., 213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children

    Roider, J., Zachary Porterfield, J., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., Morris, L., Moore, P. L., Ndung'U, T., Kløverpris, Henrik Nyhus, Goulder, P. J. R. & Leslie, A., 2019, In: Frontiers in Immunology. 10, JUL, 9 p., 1497.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis

    Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., Mahyari, E., Rogers, Z., Kløverpris, H., Sharma, P. K., Worley, A. H., Lalloo, U., Baijnath, P., Ambaram, A., Naidoo, L., Suleman, M., Madansein, R., McLaren, J. E., Ladell, K., Miners, K. L. & 8 others, Price, D. A., Behar, S. M., Nielsen, M., Kasprowicz, V. O., Leslie, A., Bishai, W. R., Ndung’u, T. & Lewinsohn, D. M., 2019, In: Communications Biology. 2, 1, 13 p., 203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Type 3 ILCs in lung disease

    Ardain, A., Porterfield, J. Z., Kløverpris, Henrik Nyhus & Leslie, A., 2019, In: Frontiers in Immunology. 10, JAN, 92.

    Research output: Contribution to journal › Review › Research › peer-review

  31. 2018
  32. Published

    Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

    Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., Sibaya, T., Moonsamy, A., McGregor, C., Phan, M. Q., Palma, A., Kløverpris, Henrik Nyhus, Leslie, A., Bobat, R., Larussa, P., Ndung'U, T., Goulder, P., Sobieszczyk, M. E. & Archary, M., Jan 2018, In: AIDS Research and Human Retroviruses. 34, 1, p. 46-55 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults

    Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2018, In: Frontiers in Immunology. 9, 14 p., 1975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells

    Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2017
  36. Published

    Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

    Simoni, Y., Fehlings, M., Kloverpris, H. N., McGovern, N., Koo, S-L., Loh, C. Y., Lim, S., Kurioka, A., Fergusson, J. R., Tang, C-L., Kam, M. H., Dennis, K., Lim, T. K. H., Fui, A. C. Y., Hoong, C. W., Chan, J. K. Y., de Lafaille, M. C., Narayanan, S., Baig, S., Shabeer, M. & 11 others, Toh, S. E. S., Tan, H. K. K., Anicete, R., Tan, E., Takano, A., Klenerman, P., Leslie, A., Tan, D. S. W., Tan, I. B., Ginhoux, F. & Newell, E. W., 17 Jan 2017, In: Immunity. 46, 1, p. 148-161

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations

    Malik, A., Adland, E., Laker, L., Kløverpris, Henrik Nyhus, Fardoos, R., Roider, J., Severinsen, M. C., Chen, F., Riddell, L., Edwards, A., Buus, Søren, Jooste, P., Matthews, P. C. & Goulder, P. J. R., 2017, In: PLOS ONE. 12, 12, 15 p., e0189612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2016
  39. Published

    Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

    Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J., Groll, A., Mori, M., Sinmyee, S., Thobakgale, C., Tudor-Williams, G., Prendergast, A. J., Kloverpris, H., Roider, J., Leslie, A., Shingadia, D. & 10 others, Brits, T., Daniels, S., Frater, J., Willberg, C. B., Walker, B. D., Ndung'u, T., Jooste, P., Moore, P. L., Morris, L. & Goulder, P., 28 Sep 2016, In: Science Translational Medicine. 8, 358, 15 p., 358ra125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression

    Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V. & 6 others, Abdool Karim, S. S., Goulder, P., Shalek, A. K., Walker, B. D., Ndung'u, T. & Leslie, A., 16 Feb 2016, In: Immunity. 44, 2, p. 391-405 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Human T cell responses to Japanese encephalitis virus in health and disease

    Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., Hussain, M., Isenman, H., Fadnis, P., Venkataswamy, M. M., Satishkumar, V., Lewthwaite, P., Kurioka, A., Krishna, S., Shankar, M. V., Ahmed, R., Begum, A., Ravi, V., Desai, A., Yoksan, S. & 7 others, Fernandez, S., Willberg, C. B., Kløverpris, Henrik Nyhus, Conlon, C., Klenerman, P., Satchidanandam, V. & Solomon, T., 2016, In: Journal of Experimental Medicine.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Role of HLA adaptation in HIV evolution

    Kløverpris, Henrik Nyhus, Leslie, A. & Goulder, P., 2016, In: Frontiers in Immunology. 6, 15 p., 665.

    Research output: Contribution to journal › Review › Research › peer-review

  45. 2015
  46. Published

    Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

    Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J. R., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T. & 1 others, Walker, B. D., 15 Sep 2015, In: Immunity. 43, 3, p. 591-604 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    CD8+ TCR Bias and Immunodominance in HIV-1 Infection

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Harndahl, M., Buus, Anette Stryhn, Carlson, J. M., Koofhethile, C., Gerritsen, B., Kesmir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, Søren, Price, D. A. & Goulder, P. J., 1 Jun 2015, In: Journal of Immunology. 194, 11, p. 5329-5345 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Human and Murine Clonal CD8+T Cell Expansions Arise during Tuberculosis Because of TCR Selection

    Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko, K., Kløverpris, Henrik Nyhus, Madansein, R., Ramsuran, D., Leslie, A., Correia-Neves, M. & Behar, S. M., May 2015, In: P L o S Pathogens. 11, 5, p. 1-29 29 p., e1004849.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

    Kløverpris, Henrik Nyhus, Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, Søren, Sewell, A. K. & Goulder, P., 20 Feb 2015, In: Retrovirology. 12, p. 1-11 11 p., 20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2014
  51. Published

    Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    HIV subtype influences HLA-B*07:02-associated HIV disease outcome

    Kløverpris, Henrik Nyhus, Adland, E., Koyanagi, M., Buus, Anette Stryhn, Harndahl, M., Matthews, P. C., Shapiro, R., Walker, B. D., Ndung'u, T., Brander, C., Takiguchi, M., Buus, Søren & Goulder, P., May 2014, In: AIDS Research and Human Retroviruses. 30, 5, p. 468-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Differential escape patterns within the dominant HLA-B*57:03-restricted HIV gag epitope reflect distinct clade-specific functional constraints

    Payne, R. P., Branch, S., Kløverpris, H., Matthews, P. C., Koofhethile, C. K., Strong, T., Adland, E., Leitman, E., Frater, J., Ndung'u, T., Hunter, E., Haubrich, R., Mothe, B., Edwards, A., Riddell, L., Chen, F., Harrigan, P. R., Brumme, Z. L., Mallal, S., John, M. & 9 others, Jooste, J. P., Shapiro, R., Deeks, S. G., Walker, B. D., Brander, C., Landis, C., Carlson, J. M., Prado, J. G. & Gouldera, P. J. R., 2014, In: Journal of Virology. 88, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2013
  55. Published

    HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, Harndahl, M., Carlson, J. M., Leslie, A. J., Chen, F., Riddell, L., Mulenga, J., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 17 Jul 2013, In: AIDS (London, England). 27, 11, p. 1717-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals

    Jackson, Andrew D., Kløverpris, Henrik Nyhus, Boffito, M., Handley, A., Atkins, M., Hayes, P., Gilmour, J., Riddel, L., Chen, F., Bailey-Tippets, M., Walker, B., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection

    Walker, L. J., Marrinan, E., Muenchhoff, M., Ferguson, J., Kløverpris, Henrik Nyhus, Cheroutre, H., Barnes, E., Goulder, P. & Klenerman, P., 2013, In: Frontiers in Immunology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T Cells

    Kløverpris, Henrik Nyhus, Payne, R. P., Sacha, J. B., Rasaiyaah, J. T., Chen, F., Takiguchi, M., Yang, O. O., Towers, G. J., Goulder, P. & Prado, J. G., 2013, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

    Kløverpris, Henrik Nyhus, Stryhn, A., Harndahl, M., Payne, R., Towers, G. J., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Leslie, A., Buus, Søren & Goulder, P., 2013, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

    Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

    Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2012
  63. Published

    Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope

    Matthews, P. C., Koyanagi, M., Kløverpris, H. N., Harndahl, M., Buus, A. S., Akahoshi, T., Gatanaga, H., Oka, S., Juarez Molina, C., Valenzuela Ponce, H., Avila Rios, S., Cole, D., Carlson, J., Payne, R. P., Ogwu, A., Bere, A., Ndung'u, T., Gounder, K., Chen, F., Riddell, L. & 11 others, Luzzi, G., Shapiro, R., Brander, C., Walker, B., Sewell, A. K., Reyes Teran, G., Heckerman, D., Hunter, E., Buus, Søren, Takiguchi, M. & Goulder, P. J. R., Dec 2012, In: Journal of Virology. 86, 23, p. 12643-12654 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    HIV control through a single nucleotide on the HLA-B locus

    Kløverpris, Henrik Nyhus, Harndahl, M., Leslie, A. J., Carlson, J. M., Ismail, N., van der Stok, M., Huang, K. G., Chen, F., Riddell, L., Steyn, D., Goedhals, D., van Vuuren, C., Frater, J., Walker, B. D., Carrington, M., Ndung'u, T., Buus, Søren & Goulder, P., Nov 2012, In: Journal of Virology. 86, 21, p. 11493-11500 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Identification of conserved subdominant HIV Type 1 CD8(+) T Cell epitopes restricted within common HLA Supertypes for therapeutic HIV Type 1 vaccines

    Karlsson, I., Kløverpris, Henrik Nyhus, Jensen, K. J., Buus, Anette Stryhn, Buus, Søren, Karlsson, A., Vinner, L., Goulder, P. & Fomsgaard, A., Nov 2012, In: AIDS Research and Human Retroviruses. 28, 11, p. 1434-1443 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, van der Stok, M., Harndahl, M., Payne, R. P., Matthews, P. C., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 2012, In: Journal of Virology. 86, 2, p. 919-29 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. 2011
  68. Published

    High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo

    Simmons, R., Sharp, C., Sims, S., Kløverpris, Henrik Nyhus, Goulder, P., Simmonds, P., Bowness, P. & Klenerman, P., 2011, In: Journal of Infectious Diseases.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Sequence analysis of HIV-1 isolates from Guinea-Bissau: Selection of vaccine epitopes relevant in both West African and European countries

    Vinner, Lasse, Holmgren, B., Jensen, K. J., Esbjornsson, J., Borggren, M., Hentze, J. L., Karlsson, I., Andresen, B. S., Gram, G. J., Kløverpris, Henrik Nyhus, Aaby, P., da Silva, Z. J., Fenyö, E. & Fomsgaard, A., 2011, In: APMIS. 119, 8, p. 487-497

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. 2010
  71. Published

    Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours

    Kløverpris, Henrik Nyhus, Fomsgaard, A., Handley, A., Ackland, J., Sullivan, M. & Goulder, P., Apr 2010, In: Journal of Immunological Methods. 356, 1-2, p. 70-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B*2705-restricted CD8+ T cells

    Payne, R. P., Kløverpris, Henrik Nyhus, Sacha, J. B., Brumme, Z., Brumme, C., Buus, Søren, Sims, S., Hickling, S., Riddell, L., Chen, F., Luzzi, G., Edwards, A., Phillips, R., Prado, J. G. & Goulder, P. J. R., 2010, In: Journal of Virology. 84, 20, p. 10543-10557

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. 2007
  74. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals

    Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 43835678