Henrik Nyhus Kløverpris
Associate Professor
Immunology
Nørre Allé 14
2200 København N
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High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo
Simmons, R., Sharp, C., Sims, S., Kløverpris, Henrik Nyhus, Goulder, P., Simmonds, P., Bowness, P. & Klenerman, P., 2011, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
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High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults
Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2018, In: Frontiers in Immunology. 9, 14 p., 1975.Research output: Contribution to journal › Journal article › Research › peer-review
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Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency
Simoni, Y., Fehlings, M., Kloverpris, H. N., McGovern, N., Koo, S-L., Loh, C. Y., Lim, S., Kurioka, A., Fergusson, J. R., Tang, C-L., Kam, M. H., Dennis, K., Lim, T. K. H., Fui, A. C. Y., Hoong, C. W., Chan, J. K. Y., de Lafaille, M. C., Narayanan, S., Baig, S., Shabeer, M. & 11 others, , 17 Jan 2017, In: Immunity. 46, 1, p. 148-161Research output: Contribution to journal › Journal article › Research › peer-review
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Human T cell responses to Japanese encephalitis virus in health and disease
Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., Hussain, M., Isenman, H., Fadnis, P., Venkataswamy, M. M., Satishkumar, V., Lewthwaite, P., Kurioka, A., Krishna, S., Shankar, M. V., Ahmed, R., Begum, A., Ravi, V., Desai, A., Yoksan, S. & 7 others, , 2016, In: Journal of Experimental Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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Human and Murine Clonal CD8+T Cell Expansions Arise during Tuberculosis Because of TCR Selection
Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko, K., Kløverpris, Henrik Nyhus, Madansein, R., Ramsuran, D., Leslie, A., Correia-Neves, M. & Behar, S. M., May 2015, In: P L o S Pathogens. 11, 5, p. 1-29 29 p., e1004849.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of conserved subdominant HIV Type 1 CD8(+) T Cell epitopes restricted within common HLA Supertypes for therapeutic HIV Type 1 vaccines
Karlsson, I., Kløverpris, Henrik Nyhus, Jensen, K. J., Buus, Anette Stryhn, Buus, Søren, Karlsson, A., Vinner, L., Goulder, P. & Fomsgaard, A., Nov 2012, In: AIDS Research and Human Retroviruses. 28, 11, p. 1434-1443 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations
Malik, A., Adland, E., Laker, L., Kløverpris, Henrik Nyhus, Fardoos, R., Roider, J., Severinsen, M. C., Chen, F., Riddell, L., Edwards, A., Buus, Søren, Jooste, P., Matthews, P. C. & Goulder, P. J. R., 2017, In: PLOS ONE. 12, 12, 15 p., e0189612.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children
Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2019, In: Frontiers in Immunology. 10, FEB, 12 p., 213.Research output: Contribution to journal › Journal article › Research › peer-review
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Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy
Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung'u, T., Shalek, A. K., Goulder, P., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Cell Reports. 32, 11, 108153.Research output: Contribution to journal › Journal article › Research › peer-review
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Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression
Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V. & 6 others, , 16 Feb 2016, In: Immunity. 44, 2, p. 391-405 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection
Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.Research output: Contribution to journal › Journal article › Research › peer-review
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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J. R., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T. & 1 others, , 15 Sep 2015, In: Immunity. 43, 3, p. 591-604 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells
Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.Research output: Contribution to journal › Journal article › Research › peer-review
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Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy
Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., Sibaya, T., Moonsamy, A., McGregor, C., Phan, M. Q., Palma, A., Kløverpris, Henrik Nyhus, Leslie, A., Bobat, R., Larussa, P., Ndung'U, T., Goulder, P., Sobieszczyk, M. E. & Archary, M., Jan 2018, In: AIDS Research and Human Retroviruses. 34, 1, p. 46-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nef-specific CD8+ T cell responses contribute to HIV-1 immune control
Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9Research output: Contribution to journal › Journal article › Research › peer-review
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Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals
Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells
Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells
Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection
Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J., Groll, A., Mori, M., Sinmyee, S., Thobakgale, C., Tudor-Williams, G., Prendergast, A. J., Kloverpris, H., Roider, J., Leslie, A., Shingadia, D. & 10 others, , 28 Sep 2016, In: Science Translational Medicine. 8, 358, 15 p., 358ra125.Research output: Contribution to journal › Journal article › Research › peer-review
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Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S. H., Giandhari, J. & 32 others, , 2022, In: Nature. 602, 7898, p. 654-656 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Omicron infection enhances Delta antibody immunity in vaccinated persons
Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., Naidoo, T. & 31 others, , 2022, In: Nature. 607, 7918, p. 356-359 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children
Roider, J., Zachary Porterfield, J., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., Morris, L., Moore, P. L., Ndung'U, T., Kløverpris, Henrik Nyhus, Goulder, P. J. R. & Leslie, A., 2019, In: Frontiers in Immunology. 10, JUL, 9 p., 1497.Research output: Contribution to journal › Journal article › Research › peer-review
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Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load
Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of HLA adaptation in HIV evolution
Kløverpris, Henrik Nyhus, Leslie, A. & Goulder, P., 2016, In: Frontiers in Immunology. 6, 15 p., 665.Research output: Contribution to journal › Review › Research › peer-review
Sequence analysis of HIV-1 isolates from Guinea-Bissau: Selection of vaccine epitopes relevant in both West African and European countries
Vinner, Lasse, Holmgren, B., Jensen, K. J., Esbjornsson, J., Borggren, M., Hentze, J. L., Karlsson, I., Andresen, B. S., Gram, G. J., Kløverpris, Henrik Nyhus, Aaby, P., da Silva, Z. J., Fenyö, E. & Fomsgaard, A., 2011, In: APMIS. 119, 8, p. 487-497Research output: Contribution to journal › Journal article › Research › peer-review
ID: 43835678
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Role of HLA adaptation in HIV evolution
Research output: Contribution to journal › Review › Research › peer-review
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Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy
Research output: Contribution to journal › Journal article › Research › peer-review
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Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published