Henrik Nyhus Kløverpris
Associate Professor
Immunology
Nørre Allé 14
2200 København N
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A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals
Jackson, Andrew D., Kløverpris, Henrik Nyhus, Boffito, M., Handley, A., Atkins, M., Hayes, P., Gilmour, J., Riddel, L., Chen, F., Bailey-Tippets, M., Walker, B., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.Research output: Contribution to journal › Journal article › Research › peer-review
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A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape
Kløverpris, Henrik Nyhus, Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, Søren, Sewell, A. K. & Goulder, P., 20 Feb 2015, In: Retrovirology. 12, p. 1-11 11 p., 20.Research output: Contribution to journal › Journal article › Research › peer-review
A simple, robust flow cytometry-based whole blood assay for investigating sex differential interferon alpha production by plasmacytoid dendritic cells
Sampson, O., Lim, N., White, J., Vieira, V., Kløverpris, Henrik Nyhus, Adland, E., Conlon, C., Skelly, D., Jones, L., Stafford, L., Jamsen, A., Barnes, E., Dunachie, S., Frater, J., Klenerman, P., Altfeld, M. & Goulder, P., 2022, In: Journal of Immunological Methods. 504, 113263.Research output: Contribution to journal › Journal article › Research › peer-review
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CD8+ TCR Bias and Immunodominance in HIV-1 Infection
Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Harndahl, M., Buus, Anette Stryhn, Carlson, J. M., Koofhethile, C., Gerritsen, B., Kesmir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, Søren, Price, D. A. & Goulder, P. J., 1 Jun 2015, In: Journal of Immunology. 194, 11, p. 5329-5345 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CD8αα expression marks terminally differentiated human CD8+ T cells expanded in chronic viral infection
Walker, L. J., Marrinan, E., Muenchhoff, M., Ferguson, J., Kløverpris, Henrik Nyhus, Cheroutre, H., Barnes, E., Goulder, P. & Klenerman, P., 2013, In: Frontiers in Immunology.Research output: Contribution to journal › Journal article › Research › peer-review
Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life
Attaf, M., Roider, J., Malik, A., Rius Rafael, C., Dolton, G., Predergast, A. J., Leslie, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Sewell, A. K. & Goulder, P. J., 2020, In: Frontiers in Immunology. 11, 1587.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children
Muenchhoff, M., Adland, E., Roider, J., Kløverpris, Henrik Nyhus, Leslie, A., Boehm, S., Keppler, O. T., Ndung'u, T. & Goulder, P. J. R., 2019, In: The Journal of Infectious Diseases. 219, 9, p. 1407-1417 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope
Matthews, P. C., Koyanagi, M., Kløverpris, H. N., Harndahl, M., Buus, A. S., Akahoshi, T., Gatanaga, H., Oka, S., Juarez Molina, C., Valenzuela Ponce, H., Avila Rios, S., Cole, D., Carlson, J., Payne, R. P., Ogwu, A., Bere, A., Ndung'u, T., Gounder, K., Chen, F., Riddell, L. & 11 others, , Dec 2012, In: Journal of Virology. 86, 23, p. 12643-12654 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Differential escape patterns within the dominant HLA-B*57:03-restricted HIV gag epitope reflect distinct clade-specific functional constraints
Payne, R. P., Branch, S., Kløverpris, H., Matthews, P. C., Koofhethile, C. K., Strong, T., Adland, E., Leitman, E., Frater, J., Ndung'u, T., Hunter, E., Haubrich, R., Mothe, B., Edwards, A., Riddell, L., Chen, F., Harrigan, P. R., Brumme, Z. L., Mallal, S., John, M. & 9 others, , 2014, In: Journal of Virology. 88, 9Research output: Contribution to journal › Journal article › Research › peer-review
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Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours
Kløverpris, Henrik Nyhus, Fomsgaard, A., Handley, A., Ackland, J., Sullivan, M. & Goulder, P., Apr 2010, In: Journal of Immunological Methods. 356, 1-2, p. 70-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct Immunoglobulin Fc Glycosylation Patterns Are Associated with Disease Nonprogression and Broadly Neutralizing Antibody Responses in Children with HIV Infection
Muenchhoff, M., Chung, A. W., Roider, J., Dugast, A. S., Richardson, S., Kløverpris, Henrik Nyhus, Leslie, A., Ndung’u, T., Moore, P., Alter, G. & Gouldera, P. J. R., 2020, In: mSphere. 5, 6, p. 1-16 e00880-20.Research output: Contribution to journal › Journal article › Research › peer-review
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Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T Cells
Kløverpris, Henrik Nyhus, Payne, R. P., Sacha, J. B., Rasaiyaah, J. T., Chen, F., Takiguchi, M., Yang, O. O., Towers, G. J., Goulder, P. & Prado, J. G., 2013, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B*2705-restricted CD8+ T cells
Payne, R. P., Kløverpris, Henrik Nyhus, Sacha, J. B., Brumme, Z., Brumme, C., Buus, Søren, Sims, S., Hickling, S., Riddell, L., Chen, F., Luzzi, G., Edwards, A., Phillips, R., Prado, J. G. & Goulder, P. J. R., 2010, In: Journal of Virology. 84, 20, p. 10543-10557Research output: Contribution to journal › Journal article › Research › peer-review
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity
Riou, C., Keeton, R., Moyo-Gwete, T., Hermanus, T., Kgagudi, P., Baguma, R., Valley-Omar, Z., Smith, M., Tegally, H., Doolabh, D., Iranzadeh, A., Tyers, L., Mutavhatsindi, H., Tincho, M. B., Benede, N., Marais, G., Chinhoyi, L. R., Mennen, M., Skelem, S., du Bruyn, E. & 31 others, , 2022, In: Science Translational Medicine. 14, 631, eabj6824.Research output: Contribution to journal › Journal article › Research › peer-review
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Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma
Cele, S., Network for Genomic Surveillance in South Africa, N. F. G. S. I. S. A. & COMMIT-KZN Team, C. T., 2021, In: Nature. 593, 7857, p. 142-146 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, , 2019, In: Nature. 570, 7762, p. 528-532Research output: Contribution to journal › Letter › Research › peer-review
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HIV control through a single nucleotide on the HLA-B locus
Kløverpris, Henrik Nyhus, Harndahl, M., Leslie, A. J., Carlson, J. M., Ismail, N., van der Stok, M., Huang, K. G., Chen, F., Riddell, L., Steyn, D., Goedhals, D., van Vuuren, C., Frater, J., Walker, B. D., Carrington, M., Ndung'u, T., Buus, Søren & Goulder, P., Nov 2012, In: Journal of Virology. 86, 21, p. 11493-11500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.Research output: Contribution to journal › Journal article › Research › peer-review
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HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway
Krause, R., Snyman, J., Shi-Hsia, H., Muema, D., Karim, F., Ganga, Y., Ngoepe, A., Zungu, Y., Gazy, I., Bernstein, M., Khan, K., Mazibuko, M., Mthabela, N., Ramjit, D., Limbo, O., Jardine, J., Sok, D., Wilson, I. A., Hanekom, W., Sigal, A. & 4 others, , 2022, In: eLife. 11, e79924.Research output: Contribution to journal › Journal article › Research › peer-review
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HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control
Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., Nguyen, S. & 6 others, , 2022, In: Frontiers in Immunology. 13, 912038.Research output: Contribution to journal › Journal article › Research › peer-review
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HIV status alters disease severity and immune cell responses in beta variant sars-COV-2 infection wave
COMMIT-KZN Team, C. T., 2021, In: eLife. 10, e67397.Research output: Contribution to journal › Journal article › Research › peer-review
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HIV subtype influences HLA-B*07:02-associated HIV disease outcome
Kløverpris, Henrik Nyhus, Adland, E., Koyanagi, M., Buus, Anette Stryhn, Harndahl, M., Matthews, P. C., Shapiro, R., Walker, B. D., Ndung'u, T., Brander, C., Takiguchi, M., Buus, Søren & Goulder, P., May 2014, In: AIDS Research and Human Retroviruses. 30, 5, p. 468-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective
Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, Harndahl, M., Carlson, J. M., Leslie, A. J., Chen, F., Riddell, L., Mulenga, J., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 17 Jul 2013, In: AIDS (London, England). 27, 11, p. 1717-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control
Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, van der Stok, M., Harndahl, M., Payne, R. P., Matthews, P. C., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 2012, In: Journal of Virology. 86, 2, p. 919-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01
Kløverpris, Henrik Nyhus, Stryhn, A., Harndahl, M., Payne, R., Towers, G. J., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Leslie, A., Buus, Søren & Goulder, P., 2013, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo
Simmons, R., Sharp, C., Sims, S., Kløverpris, Henrik Nyhus, Goulder, P., Simmonds, P., Bowness, P. & Klenerman, P., 2011, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
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High-frequency, functional HIV-specific T-follicular helper and regulatory cells are present within germinal centers in children but not adults
Roider, J., Maehara, T., Ngoepe, A., Ramsuran, D., Muenchhoff, M., Adland, E., Aicher, T., Kazer, S. W., Jooste, P., Karim, F., Kuhn, W., Shalek, A. K., Ndung'u, T., Morris, L., Moore, P. L., Pillai, S., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2018, In: Frontiers in Immunology. 9, 14 p., 1975.Research output: Contribution to journal › Journal article › Research › peer-review
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Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency
Simoni, Y., Fehlings, M., Kloverpris, H. N., McGovern, N., Koo, S-L., Loh, C. Y., Lim, S., Kurioka, A., Fergusson, J. R., Tang, C-L., Kam, M. H., Dennis, K., Lim, T. K. H., Fui, A. C. Y., Hoong, C. W., Chan, J. K. Y., de Lafaille, M. C., Narayanan, S., Baig, S., Shabeer, M. & 11 others, , 17 Jan 2017, In: Immunity. 46, 1, p. 148-161Research output: Contribution to journal › Journal article › Research › peer-review
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Human T cell responses to Japanese encephalitis virus in health and disease
Turtle, L., Bali, T., Buxton, G., Chib, S., Chan, S., Soni, M., Hussain, M., Isenman, H., Fadnis, P., Venkataswamy, M. M., Satishkumar, V., Lewthwaite, P., Kurioka, A., Krishna, S., Shankar, M. V., Ahmed, R., Begum, A., Ravi, V., Desai, A., Yoksan, S. & 7 others, , 2016, In: Journal of Experimental Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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Human and Murine Clonal CD8+T Cell Expansions Arise during Tuberculosis Because of TCR Selection
Nunes-Alves, C., Booty, M. G., Carpenter, S. M., Rothchild, A. C., Martin, C. J., Desjardins, D., Steblenko, K., Kløverpris, Henrik Nyhus, Madansein, R., Ramsuran, D., Leslie, A., Correia-Neves, M. & Behar, S. M., May 2015, In: P L o S Pathogens. 11, 5, p. 1-29 29 p., e1004849.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of conserved subdominant HIV Type 1 CD8(+) T Cell epitopes restricted within common HLA Supertypes for therapeutic HIV Type 1 vaccines
Karlsson, I., Kløverpris, Henrik Nyhus, Jensen, K. J., Buus, Anette Stryhn, Buus, Søren, Karlsson, A., Vinner, L., Goulder, P. & Fomsgaard, A., Nov 2012, In: AIDS Research and Human Retroviruses. 28, 11, p. 1434-1443 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations
Malik, A., Adland, E., Laker, L., Kløverpris, Henrik Nyhus, Fardoos, R., Roider, J., Severinsen, M. C., Chen, F., Riddell, L., Edwards, A., Buus, Søren, Jooste, P., Matthews, P. C. & Goulder, P. J. R., 2017, In: PLOS ONE. 12, 12, 15 p., e0189612.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased regulatory T-cell activity and enhanced T-cell homeostatic signaling in slow progressing HIV-infected children
Roider, J., Ngoepe, A., Muenchhoff, M., Adland, E., Groll, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Goulder, P. & Leslie, A., 2019, In: Frontiers in Immunology. 10, FEB, 12 p., 213.Research output: Contribution to journal › Journal article › Research › peer-review
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Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy
Singh, A., Kazer, S. W., Roider, J., Krista, K. C., Millar, J., Asowata, O. E., Ngoepe, A., Ramsuran, D., Fardoos, R., Ardain, A., Muenchhoff, M., Kuhn, W., Karim, F., Ndung'u, T., Shalek, A. K., Goulder, P., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Cell Reports. 32, 11, 108153.Research output: Contribution to journal › Journal article › Research › peer-review
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Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-Infection in the Absence of Viral Suppression
Kløverpris, H. N., Kazer, S. W., Mjösberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V. & 6 others, , 16 Feb 2016, In: Immunity. 44, 2, p. 391-405 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection
Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.Research output: Contribution to journal › Journal article › Research › peer-review
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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J. R., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T. & 1 others, , 15 Sep 2015, In: Immunity. 43, 3, p. 591-604 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells
Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.Research output: Contribution to journal › Journal article › Research › peer-review
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Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy
Muenchhoff, M., Healy, M., Singh, R., Roider, J., Groll, A., Kindra, C., Sibaya, T., Moonsamy, A., McGregor, C., Phan, M. Q., Palma, A., Kløverpris, Henrik Nyhus, Leslie, A., Bobat, R., Larussa, P., Ndung'U, T., Goulder, P., Sobieszczyk, M. E. & Archary, M., Jan 2018, In: AIDS Research and Human Retroviruses. 34, 1, p. 46-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nef-specific CD8+ T cell responses contribute to HIV-1 immune control
Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9Research output: Contribution to journal › Journal article › Research › peer-review
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Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals
Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells
Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells
Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection
Muenchhoff, M., Adland, E., Karimanzira, O., Crowther, C., Pace, M., Csala, A., Leitman, E., Moonsamy, A., McGregor, C., Hurst, J., Groll, A., Mori, M., Sinmyee, S., Thobakgale, C., Tudor-Williams, G., Prendergast, A. J., Kloverpris, H., Roider, J., Leslie, A., Shingadia, D. & 10 others, , 28 Sep 2016, In: Science Translational Medicine. 8, 358, 15 p., 358ra125.Research output: Contribution to journal › Journal article › Research › peer-review
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Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S. H., Giandhari, J. & 32 others, , 2022, In: Nature. 602, 7898, p. 654-656 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Omicron infection enhances Delta antibody immunity in vaccinated persons
Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., Naidoo, T. & 31 others, , 2022, In: Nature. 607, 7918, p. 356-359 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children
Roider, J., Zachary Porterfield, J., Ogongo, P., Muenchhoff, M., Adland, E., Groll, A., Morris, L., Moore, P. L., Ndung'U, T., Kløverpris, Henrik Nyhus, Goulder, P. J. R. & Leslie, A., 2019, In: Frontiers in Immunology. 10, JUL, 9 p., 1497.Research output: Contribution to journal › Journal article › Research › peer-review
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Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load
Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of HLA adaptation in HIV evolution
Kløverpris, Henrik Nyhus, Leslie, A. & Goulder, P., 2016, In: Frontiers in Immunology. 6, 15 p., 665.Research output: Contribution to journal › Review › Research › peer-review
Sequence analysis of HIV-1 isolates from Guinea-Bissau: Selection of vaccine epitopes relevant in both West African and European countries
Vinner, Lasse, Holmgren, B., Jensen, K. J., Esbjornsson, J., Borggren, M., Hentze, J. L., Karlsson, I., Andresen, B. S., Gram, G. J., Kløverpris, Henrik Nyhus, Aaby, P., da Silva, Z. J., Fenyö, E. & Fomsgaard, A., 2011, In: APMIS. 119, 8, p. 487-497Research output: Contribution to journal › Journal article › Research › peer-review
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Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals
Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals
Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence conservation of subdominant HLA-A2-binding CTL epitopes in HIV-1 clinical isolates and CD8<sup>+</sup> T-lymphocyte cross-recognition may explain the immune reaction in infected individuals
Thorn, M., Tang, S., Therrien, D., Kløverpris, Henrik Nyhus, Vinner, Lasse, Kronborg, Gitte, Gerstoft, Jan, Corbet, S. & Fomsgaard, A., 2007, In: APMIS.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and with Human Immunodeficiency Virus on Antiretroviral Therapy during the First South African Infection Wave
Snyman, J., Hwa, S. H., Krause, R., Muema, D., Reddy, T., Ganga, Y., Karim, F., Leslie, A., Sigal, A., Ndung'U, T., Archary, M., Dullabh, K. J., Goulder, P., Harling, G., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Klein, N., Kloverpris, H. & 13 others, , 2022, In: Clinical Infectious Diseases. 75, 1, p. E249-E256Research output: Contribution to journal › Journal article › Research › peer-review
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Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation
Kummerlowe, C., Mwakamui, S., Hughes, T. K., Mulugeta, N., Mudenda, V., Besa, E., Zyambo, K., Shay, J. E. S., Fleming, I., Vukovic, M., Doran, B. A., Aicher, T. P., Wadsworth, M. H., Bramante, J. T., Uchida, A. M., Fardoos, R., Asowata, O. E., Herbert, N., Yilmaz, Ö. H., Kløverpris, H. N. & 6 others, , 2022, In: Science Translational Medicine. 14, 660, eabi8633.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype
Vieira, V., Lim, N., Singh, A., Leitman, E., Dsouza, R., Adland, E., Muenchhoff, M., Roider, J., Lopez, M. M., Carabelli, J., Giandhari, J., Groll, A., Jooste, P., Prado, J. G., Thobakgale, C., Dong, K., Kiepiela, P., Prendergast, A. J., Tudor-Williams, G., Frater, J. & 6 others, , 2023, In: JCI insight. 8, 3, e156049.Research output: Contribution to journal › Journal article › Research › peer-review
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T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy
Lustig, G., Cele, S., Karim, F., Derache, A., Ngoepe, A., Khan, K., Gosnell, B. I., Moosa, M. Y. S., Ntshuba, N., Marais, S., Jeena, P. M., Govender, K., Adamson, J., Kløverpris, Henrik Nyhus, Gupta, R. K., Harrichandparsad, R., Patel, V. B. & Sigal, A., 2021, In: PLOS Pathogens. 17, 9, 21 p., e1009871.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis
Wong, E. B., Gold, M. C., Meermeier, E. W., Xulu, B. Z., Khuzwayo, S., Sullivan, Z. A., Mahyari, E., Rogers, Z., Kløverpris, H., Sharma, P. K., Worley, A. H., Lalloo, U., Baijnath, P., Ambaram, A., Naidoo, L., Suleman, M., Madansein, R., McLaren, J. E., Ladell, K., Miners, K. L. & 8 others, , 2019, In: Communications Biology. 2, 1, 13 p., 203.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung
Ogongo, P., Tezera, L. B., Ardain, A., Nhamoyebonde, S., Ramsuran, D., Singh, A., Ng’oepe, A., Karim, F., Naidoo, T., Khan, K., Dullabh, K. J., Fehlings, M., Lee, B. H., Nardin, A., Lindestam Arlehamn, C. S., Sette, A., Behar, S. M., Steyn, A. J. C., Madansein, R., Kløverpris, H. N. & 2 others, , 2021, In: Journal of Clinical Investigation. 131, 10, e142014.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 3 ILCs in lung disease
Ardain, A., Porterfield, J. Z., Kløverpris, Henrik Nyhus & Leslie, A., 2019, In: Frontiers in Immunology. 10, JAN, 92.Research output: Contribution to journal › Review › Research › peer-review
- Published
Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection
Magnoumba, M., Singh, A., Ogongo, P., Roider, J., Asowata, O., Fehlings, M., Karim, F., Ndung'u, T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2020, In: Frontiers in Immunology. 11, 579743.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 43835678
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Role of HLA adaptation in HIV evolution
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Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy
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Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells
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