Henrik Nyhus Kløverpris

Henrik Nyhus Kløverpris

Associate Professor

ORCID: 0000-0002-2165-3313

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  1. Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

    Adland, E., Carlson, J. M., Paioni, P., Kløverpris, Henrik Nyhus, Shapiro, R., Ogwu, A., Riddell, L., Luzzi, G., Chen, F., Balachandran, T., Heckerman, D., Stryhn, A., Edwards, A., Ndung'u, T., Walker, B. D., Buus, Søren, Goulder, P. & Matthews, P. C., 2013, In: PLoS ONE. 8, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Type 3 ILCs in lung disease

    Ardain, A., Porterfield, J. Z., Kløverpris, Henrik Nyhus & Leslie, A., 2019, In: Frontiers in Immunology. 10, JAN, 92.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

    Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, Henrik Nyhus, Colonna, M., Leslie, A. & Khader, S. A., 2019, In: Nature. 570, 7762, p. 528-532

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    Irreversible depletion of intestinal CD4+ T cells is associated with T cell activation during chronic HIV infection

    Asowata, O. E., Singh, A., Ngoepe, A., Herbert, N., Fardoos, R., Reddy, K., Zungu, Y., Nene, F., Mthabela, N., Ramjit, D., Karim, F., Govender, K., Ndung’u, T., Zachary Porterfield, J., Adamson, J. H., Madela, F. G., Manzini, V. T., Anderson, F., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 22, e146162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells

    Attaf, M., Malik, A., Severinsen, M. C., Roider, J., Ogongo, P., Buus, Søren, Ndung'u, T., Leslie, A., Kløverpris, Henrik Nyhus, Matthews, P. C., Sewell, A. K. & Goulder, P., 2018, In: Frontiers in Immunology. 9, 2539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life

    Attaf, M., Roider, J., Malik, A., Rius Rafael, C., Dolton, G., Predergast, A. J., Leslie, A., Ndung'u, T., Kløverpris, Henrik Nyhus, Sewell, A. K. & Goulder, P. J., 2020, In: Frontiers in Immunology. 11, 1587.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma

    Cele, S., Network for Genomic Surveillance in South Africa, N. F. G. S. I. S. A. & COMMIT-KZN Team, C. T., 2021, In: Nature. 593, 7857, p. 142-146 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

    Cele, S., Jackson, L., Khoury, D. S., Khan, K., Moyo-Gwete, T., Tegally, H., San, J. E., Cromer, D., Scheepers, C., Amoako, D. G., Karim, F., Bernstein, M., Lustig, G., Archary, D., Smith, M., Ganga, Y., Jule, Z., Reedoy, K., Hwa, S. H., Giandhari, J. & 32 others, Blackburn, J. M., Gosnell, B. I., Abdool Karim, S. S., Hanekom, W., Davies, M. A., Hsiao, M., Martin, D., Mlisana, K., Wibmer, C. K., Williamson, C., York, D., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Magula, N., Manickchund, N., Marakalala, M., Mazibuko, M., Moshabela, M., Mthabela, N., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Ngcobo, N., Nyamande, K., Patel, V., NGS-SA, N. & COMMIT-KZN Team, C. T., 2022, In: Nature. 602, 7898, p. 654-656 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control

    Fardoos, R., Nyquist, S. K., Asowata, O. E., Kazer, S. W., Singh, A., Ngoepe, A., Giandhari, J., Mthabela, N., Ramjit, D., Singh, S., Karim, F., Buus, S., Anderson, F., Porterfield, J. Z., Sibiya, A. L., Bipath, R., Moodley, K., Kuhn, W., Berger, B., Nguyen, S. & 6 others, de Oliveira, T., Ndung’u, T., Goulder, P., Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2022, In: Frontiers in Immunology. 13, 912038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals

    Jackson, Andrew D., Kløverpris, Henrik Nyhus, Boffito, M., Handley, A., Atkins, M., Hayes, P., Gilmour, J., Riddel, L., Chen, F., Bailey-Tippets, M., Walker, B., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Nonhuman TRIM5 variants enhance recognition of HIV-1-infected cells by CD8<sup>+</sup>T cells

    Jimenez-Moyano, E., Ruiz, A., Kløverpris, Henrik Nyhus, Rodriguez-Plata, M. T., Peña, R., Blondeau, C., Selwood, D. L., Izquierdo-Useros, N., Moris, A., Clotet, B., Goulder, P., Towers, G. J. & Prado, J. G., 2016, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    HIV status alters disease severity and immune cell responses in beta variant sars-COV-2 infection wave

    COMMIT-KZN Team, C. T., 2021, In: eLife. 10, e67397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Identification of conserved subdominant HIV Type 1 CD8(+) T Cell epitopes restricted within common HLA Supertypes for therapeutic HIV Type 1 vaccines

    Karlsson, I., Kløverpris, Henrik Nyhus, Jensen, K. J., Buus, Anette Stryhn, Buus, Søren, Karlsson, A., Vinner, L., Goulder, P. & Fomsgaard, A., Nov 2012, In: AIDS Research and Human Retroviruses. 28, 11, p. 1434-1443 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Omicron infection enhances Delta antibody immunity in vaccinated persons

    Khan, K., Karim, F., Cele, S., Reedoy, K., San, J. E., Lustig, G., Tegally, H., Rosenberg, Y., Bernstein, M., Jule, Z., Ganga, Y., Ngcobo, N., Mazibuko, M., Mthabela, N., Mhlane, Z., Mbatha, N., Miya, Y., Giandhari, J., Ramphal, Y., Naidoo, T. & 31 others, Sivro, A., Samsunder, N., Kharsany, A. B. M., Amoako, D., Bhiman, J. N., Manickchund, N., Abdool Karim, Q., Magula, N., Abdool Karim, S. S., Gray, G., Hanekom, W., von Gottberg, A., Harrichandparsad, R., Herbst, K., Jeena, P., Khoza, T., Kløverpris, Henrik Nyhus, Leslie, A., Madansein, R., Marakalala, M., Moshabela, M., Naidoo, K., Ndhlovu, Z., Ndung’u, T., Nyamande, K., Patel, V., Smit, T., Steyn, A., Wong, E., Milo, R. & COMMIT-KZN Team, C. T., 2022, In: Nature. 607, 7918, p. 356-359 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape

    Kløverpris, Henrik Nyhus, Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, Søren, Sewell, A. K. & Goulder, P., 20 Feb 2015, In: Retrovirology. 12, p. 1-11 11 p., 20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    CD8+ TCR Bias and Immunodominance in HIV-1 Infection

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Harndahl, M., Buus, Anette Stryhn, Carlson, J. M., Koofhethile, C., Gerritsen, B., Kesmir, C., Chen, F., Riddell, L., Luzzi, G., Leslie, A., Walker, B. D., Ndung'u, T., Buus, Søren, Price, D. A. & Goulder, P. J., 1 Jun 2015, In: Journal of Immunology. 194, 11, p. 5329-5345 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours

    Kløverpris, Henrik Nyhus, Fomsgaard, A., Handley, A., Ackland, J., Sullivan, M. & Goulder, P., Apr 2010, In: Journal of Immunological Methods. 356, 1-2, p. 70-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

    Kløverpris, Henrik Nyhus, Stryhn, A., Harndahl, M., Payne, R., Towers, G. J., Chen, F., Riddell, L., Walker, B. D., Ndung'u, T., Leslie, A., Buus, Søren & Goulder, P., 2013, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T Cells

    Kløverpris, Henrik Nyhus, Payne, R. P., Sacha, J. B., Rasaiyaah, J. T., Chen, F., Takiguchi, M., Yang, O. O., Towers, G. J., Goulder, P. & Prado, J. G., 2013, In: Journal of Virology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

    Kløverpris, Henrik Nyhus, Jackson, Andrew D., Handley, A., Hayes, P., Gilmour, J., Riddell, L., Chen, F., Atkins, M., Boffito, M., Walker, B. D., Ackland, J., Sullivan, M. & Goulder, P., 2013, In: PLoS ONE.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

    Kløverpris, Henrik Nyhus, Buus, Anette Stryhn, Harndahl, M., Carlson, J. M., Leslie, A. J., Chen, F., Riddell, L., Mulenga, J., Walker, B. D., Ndung'u, T., Buus, Søren & Goulder, P., 17 Jul 2013, In: AIDS (London, England). 27, 11, p. 1717-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    HIV subtype influences HLA-B*07:02-associated HIV disease outcome

    Kløverpris, Henrik Nyhus, Adland, E., Koyanagi, M., Buus, Anette Stryhn, Harndahl, M., Matthews, P. C., Shapiro, R., Walker, B. D., Ndung'u, T., Brander, C., Takiguchi, M., Buus, Søren & Goulder, P., May 2014, In: AIDS Research and Human Retroviruses. 30, 5, p. 468-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

    Kløverpris, Henrik Nyhus, McGregor, R., McLaren, J. E., Ladell, K., Buus, Anette Stryhn, Koofhethile, C., Brener, J., Chen, F., Riddell, L., Graziano, L., Klenerman, P., Leslie, A., Buus, Søren, Price, D. A. & Goulder, P., 10 Sep 2014, In: AIDS (London, England). 28, 14, p. 2007-21 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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