Hans K Hasselbalch

Hans K Hasselbalch

Clinical Professor

Member of:

  • Internal Medicine: Haematology


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  1. Published

    Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

    Andersen, Christen Bertel L, Grønbæk, Kirsten & Hasselbalch, Hans Carl, 1 Apr 2012, In: Leukemia Research. 36, 4, p. 485-487 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Association of the blood eosinophil count with hematological malignancies and mortality

    Andersen, Christen Bertel L, Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Vestergaard, H., Mesa, R., Felding, P., Olivarius, Niels de Fine & Bjerrum, O. W., Mar 2015, In: American Journal of Hematology. 90, 3, p. 225-229 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones

    Andersen, Christen Bertel L, Asmar, F., Klausen, T., Hasselbalch, Hans Carl & Grønbæk, K., 2012, In: Leukemia Research Reports. 2, 1, p. 1-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

    Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Myeloproliferative Neoplasms in Danish Twins

    Andersen, M. A., Bjerrum, O. W., Ranjan, A., Skov, V., Kruse, T. A., Thomassen, M., Skytthe, A., Hasselbalch, Hans Carl & Christensen, K., 2018, In: Acta Haematologica. 139, 3, p. 195-198 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development

    Andersen, M., Sajid, Z., Pedersen, R. K., Gudmand-hoeyer, J., Ellervik, C., Skov, V., Kjær, L., Pallisgaard, N., Kruse, T. A., Thomassen, M., Troelsen, J., Hasselbalch, Hans Carl & Ottesen, J. T., 2017, In: PLOS ONE. 12, 8, 18 p., e0183620.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Age-Related Macular Degeneration in Patients With Chronic Myeloproliferative Neoplasms

    Bak, M., Sørensen, Torben Lykke, Flachs, E. M., Zwisler, A., Juel, K., Frederiksen, H. & Hasselbalch, Hans Carl, 2017, In: JAMA Ophthalmology. 135, 8, p. 835-843

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European leukemiaNet

    Barbui, T., Barosi, G., Birgegard, G., Cervantes, F., Finazzi, G., Griesshammer, M., Harrison, C., Hasselbalch, H. C., Hehlmann, R., Hoffman, R., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Vannucchi, A. M., Reiter, A., Silver, R. T., Verstovsek, S. & 1 others, Tefferi, A., 20 Feb 2011, In: Journal of Clinical Oncology. 29, 6, p. 761-770 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Philadelphia chromosome-negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet

    Barbui, T., Tefferi, A., Vannucchi, A. M., Passamonti, F., Silver, R. T., Hoffman, R., Verstovsek, S., Mesa, R., Kiladjian, J-J., Hehlmann, R., Reiter, A., Cervantes, F., Harrison, C., Mc Mullin, M. F., Hasselbalch, H. C., Koschmieder, S., Marchetti, M., Bacigalupo, A., Finazzi, G., Kroeger, N. & 3 others, Griesshammer, M., Birgegard, G. & Barosi, G., 2018, In: Leukemia. 32, 5, p. 1057-1069

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group

    Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Association of the blood eosinophil count with end-organ symptoms

    Bjerrum, O. W., Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Lind, B. & Andersen, Christen Bertel L, 2019, In: Annals of Medicine and Surgery. 45, p. 11-18

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state

    Bjørn, M. E., Andersen, Christen Bertel L, Jensen, M. K. & Hasselbalch, Hans Carl, 2014, In: European Journal of Haematology. 93, 3, p. 224-228 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Minimal residual disease or cure in MPNs? Rationales and perspectives on combination therapy with interferon-alpha2 and ruxolitinib

    Bjørn, M. E. & Hasselbalch, Hans Carl, 2017, In: Expert Review of Hematology. 10, 5, p. 393-404

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Anxiety and depression in patients with Philadelphia-negative myeloproliferative neoplasms: a nationwide population-based survey in Denmark

    Brochmann, N., Flachs, E. M., Christensen, A. I., Bak, M., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl, Zwisler, A. & Rottmann, N., 2019, In: Clinical Epidemiology. 11, p. 23-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents

    Brochmann, N., Flachs, E. M., Christensen, A. I., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl & Zwisler, A., 2017, In: Clinical Epidemiology. 9, p. 141-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms

    Brochmann, N., Zwisler, A., Kjerholt, M., Flachs, E. M., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2016, In: Quality of Life Research. 25, 4, p. 835-846 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression

    Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, A., Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, Christina, Fassi, Daniel El , Vidal, S., Hasselbalch, Hans Carl, Andersen, Mads Hald & thor Straten, P., 2022, In: Frontiers in Immunology. 13, 866610.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Tobacco use in the Myeloproliferative neoplasms: symptom burden, patient opinions, and care

    Christensen, S. F., Scherber, R. M., Mazza, G. L., Dueck, A. C., Brochmann, N., Andersen, Christen Bertel L, Hasselbalch, Hans Carl, Mesa, R. A. & Geyer, H. L., 2021, In: BMC Cancer. 21, 1, 13 p., 691.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study

    Christensen, S. F., Svingel, L. S., Kjaersgaard, A., Stenling, A., Darvalics, B., Paulsson, B., Andersen, Christen Bertel L, Christiansen, C. F., Stentoft, J., Starklint, J., Severinsen, M. T., Clausen, M. B., Hilsoe, M. H., Hasselbalch, Hans Carl, Frederiksen, H., Mikkelsen, E. M. & Bak, M., 2022, In: European Journal of Haematology. 109, 5, p. 526-541 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Early detection of myeloproliferative neoplasms in a Danish general population study

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Kefala, Maria, Gjerdrum, Lise Mette Rahbek, Hasselbalch, Hans Carl & Ellervik, Christina, 2021, In: Leukemia. 35, 9, p. 2706-2709 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Hasselbalch, Hans Carl & Ellervik, Christina, 2019, In: Blood. 134, 5, p. 469-479

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation

    Czech, J., Cordua, S., Weinbergerova, B., Baumeister, J., Crepcia, A., Han, L., Maié, T., Costa, I. G., Denecke, B., Maurer, A., Schubert, C., Feldberg, K., Gezer, D., Brümmendorf, T. H., Müller-newen, G., Mayer, J., Racil, Z., Kubesova, B., Knudsen, T., Sørensen, A. L. & 7 others, Holmström, M., Kjær, L., Skov, V., Larsen, T. S., Hasselbalch, Hans Carl, Chatain, N. & Koschmieder, S., 2019, In: Leukemia. 33, 4, p. 995-1010

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Ellervik, Christina, Larsen, Morten Kranker, Kjær, L., Skov, V., Hasselbalch, Hans Carl & Ottesen, J. T., 2023, In: Cancer Medicine. 12, 4, p. 4218-4226

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Ottesen, J. T., 2021, In: European Journal of Haematology. 107, 6, p. 624-633 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 2849472