Erika Villanueva
Postdoc
Molecular and Cellular Pharmacology
Jagtvej 160, Building: 22-3-333
2100 København
Denmark
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2021
- Published
Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice
Villanueva, Erika Bianca, Tresse-Gommeaux, Emilie, Liu, Yawei, Duarte, J. N., Jimenez-Duran, G., Ejlerskov, P., Kretz, O., Loreth, D., Goldmann, T., Prinz, M. & Issazadeh-Navikas, Shohreh, 2021, In: Annals of Neurology. 90, 5, p. 789-807Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo
Ehrnhoefer, D. E., Southwell, A. L., Sivasubramanian, M., Qiu, X., Villanueva, Erika Bianca, Xie, Y., Waltl, S., Anderson, L., Fazeli, A., Casal, L., Felczak, B., Tsang, M. & Hayden, M. R., 15 Jan 2018, In: Human Molecular Genetics. 27, 2, p. 239-253 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease
Southwell, A. L., Kordasiewicz, H. B., Langbehn, D., Skotte, Niels Henning, Parsons, M. P., Villanueva, Erika Bianca, Caron, N. S., Østergaard, M. E., Anderson, L. M., Xie, Y., Cengio, L. D., Findlay-Black, H., Doty, C. N., Fitsimmons, B., Swayze, E. E., Seth, P. P., Raymond, L. A., Frank Bennett, C. & Hayden, M. R., 2018, In: Science Translational Medicine. 10, 461, p. 1-12 eaar3959.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles
Southwell, A. L., Skotte, N. H., Villanueva, E. B., Østergaard, M. E., Gu, X., Kordasiewicz, H. B., Kay, C., Cheung, D., Xie, Y., Waltl, S., Dal Cengio, L., Findlay-Black, H., Doty, C. N., Petoukhov, E., Iworima, D., Slama, R., Ooi, J., Pouladi, M. A., Yang, X. W., Swayze, E. E. & 2 others, , 15 Mar 2017, In: Human Molecular Genetics. 26, 6, p. 1115-1132 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes
Southwell, A. L., Smith-Dijak, A., Kay, C., Sepers, M., Villanueva, Erika Bianca, Parsons, M. P., Xie, Y., Anderson, L., Felczak, B., Waltl, S., Ko, S., Cheung, D., Dal Cengio, L., Slama, R., Petoukhov, E., Raymond, L. A. & Hayden, M. R., 1 Sep 2016, In: Human Molecular Genetics. 25, 17, p. 3654-3675 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
Southwell, A. L., Smith, S. E. P., Davis, T. R., Caron, N. S., Villanueva, Erika Bianca, Xie, Y., Collins, J. A., Ye, M. L., Sturrock, A., Leavitt, B. R., Schrum, A. G. & Hayden, M. R., 15 Jul 2015, In: Scientific Reports. 5, p. 12166Research output: Contribution to journal › Journal article › Research › peer-review
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
Southwell, A. L., Franciosi, S., Villanueva, Erika Bianca, Xie, Y., Winter, L. A., Veeraraghavan, J., Jonason, A., Felczak, B., Zhang, W., Kovalik, V., Waltl, S., Hall, G., Pouladi, M. A., Smith, E. S., Bowers, W. J., Zauderer, M. & Hayden, M. R., Apr 2015, In: Neurobiology of Disease. 76, p. 46-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides
Southwell, A. L., Skotte, Niels Henning, Kordasiewicz, H. B., Østergaard, M. E., Watt, A. T., Carroll, J. B., Doty, C. N., Villanueva, Erika Bianca, Petoukhov, E., Vaid, K., Xie, Y., Freier, S. M., Swayze, E. E., Seth, P. P., Bennett, C. F. & Hayden, M. R., Dec 2014, In: Molecular Therapy. 22, 12, p. 2093-106 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia
Little, J. P., Simtchouk, S., Schindler, S. M., Villanueva, Erika Bianca, Gill, N. E., Walker, D. G., Wolthers, K. R. & Klegeris, A., May 2014, In: Molecular and Cellular Neuroscience. 60, p. 88-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS
Østergaard, M. E., Southwell, A. L., Kordasiewicz, H., Watt, A. T., Skotte, Niels Henning, Doty, C. N., Vaid, K., Villanueva, Erika Bianca, Swayze, E. E., Bennett, C. F., Hayden, M. R. & Seth, P. P., Nov 2013, In: Nucleic Acids Research. 41, 21, p. 9634-50 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 157553808
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Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published