Dilip Narayanan
Research Consultant
Structural Biology
Jagtvej 162, Building: 30-1-128
2100 København Ø
- 2023
- Published
Small-molecule modulators of tumor necrosis factor signaling
Chédotal, H., Narayanan, Dilip, Povlsen, K., Gotfredsen, C. H., Brambilla, R., Gajhede, Michael, Bach, Anders & Clausen, M. H., 2023, In: Drug Discovery Today. 28, 6, 103575.Research output: Contribution to journal › Review › Research › peer-review
- Published
Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors
Zang, J., Peters, F., Cambet, Y., Cifuentes-Pagano, E., Hissabu, M. M. S., Dustin, C. M., Svensson, L. H., Olesen, M. M., Poulsen, M. F. L., Jacobsen, Stig, Tuelung, P. S., Narayanan, Dilip, Langkilde, Annette Eva, Gajhede, Michael, Pagano, P. J., Jaquet, V., Vilhardt, Frederik & Bach, Anders, 2023, In: Journal of Medicinal Chemistry. 66, 21, p. 14963–15005Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery
Narayanan, Dilip, Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, Michael & Bach, Anders, 2022, In: Journal of Medicinal Chemistry. 65, 21, p. 14481-14526Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds
Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Targeting the Redox Landscape in Cancer Therapy
Narayanan, Dilip, Ma, S. & Özcelik, D., 2020, In: Cancers. 12, 7, 29 p., 1706.Research output: Contribution to journal › Review › Research › peer-review
- Published
Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery
Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
Tran, K. T., Pallesen, J. S., Solbak, Sara Marie Øie, Narayanan, Dilip, Baig, A., Zang, J., Aguayo-Orozco, A., Carmona, R., Garcia, A. & Bach, Anders, 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 8028-8052Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR
Narayanan, Dilip, Gani, O. A., Gruber, F. X. & Engh, R. A., 2017, In: Journal of Cheminformatics. 9, 19 p., 43.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches
Gani, O. A., Thakkar, B., Narayanan, Dilip, Alam, K. A., Kyomuhendo, P., Rothweiler, U., Tello-Franco, V. & Engh, R. A., Oct 2015, In: Biochimica et biophysica acta. 1854, 10 Pt B, p. 1605-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Evaluating the predictivity of virtual screening for ABL kinase inhibitors to hinder drug resistance
Gani, O. A. B. S. M., Narayanan, Dilip & Engh, R. A., Nov 2013, In: Chemical Biology & Drug Design. 82, 5, p. 506-19 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 160904351
Most downloads
-
250
downloads
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
72
downloads
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
69
downloads
Targeting the Redox Landscape in Cancer Therapy
Research output: Contribution to journal › Review › Research › peer-review
Published