Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

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  1. Published

    Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

    Aderka, D., Engelmann, H., Maor, Y., Brakebusch, Cord Herbert & Wallach, D., 1992, In: Journal of Experimental Medicine. 175, 2, p. 323-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

    Akula, M. K., Ibrahim, M. X., Ivarsson, E. G., Khan, O. M., Kumar, I. T., Erlandsson, M., Karlsson, C., Xu, X., Brisslert, M., Brakebusch, Cord Herbert, Wang, D., Bokarewa, M., Sayin, V. I. & Bergo, M. O., 4 Sep 2019, In: Nature Communications. 10, 1, p. 1-13 13 p., 3975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.

    Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., Brandt, C., Löscher, W., Grimberg, D., Dresbach, T., Hempelmann, A., Hassan, H., Balschun, D., Frey, J. U., Brandstätter, J. H., Garner, C. C. & 2 others, Rosenmund, C. & Gundelfinger, E. D., 2003, In: Neuron. 37, 5, p. 787-800 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cytoskeletal stability in the auditory organ in vivo: RhoA is dispensable for wound healing but essential for hair cell development

    Anttonen, T., Belevich, I., Laos, M., Herranen, A., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2017, In: eNeuro. 4, 5, 17 p., e0149-17.2017.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    How to Bury the Dead: Elimination of Apoptotic Hair Cells from the Hearing Organ of the Mouse

    Anttonen, T., Belevich, I., Kirjavainen, A., Laos, M., Brakebusch, Cord Herbert, Jokitalo, E. & Pirvola, U., 30 Jul 2014, In: J A R O. 15, 6, p. 975-992 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood

    Anttonen, T., Kirjavainen, A., Belevich, I., Laos, M., Richardson, W. D., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2012, In: Scientific Reports. 2, p. 978

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

    Aszodi, A., Hunziker, E. B., Brakebusch, Cord Herbert & Fässler, R., 2003, In: Genes & Development. 17, 19, p. 2465-79 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Opposing roles for RhoH GTPase during T-cell migration and activation

    Baker, C. M., Comrie, W. A., Hyun, Y., Chung, H., Fedorchuk, C. A., Lim, K., Brakebusch, Cord Herbert, McGrath, J. L., Waugh, R. E., Meier-Schellersheim, M. & Kim, M., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. 10474-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity

    Bauer, M., Brakebusch, Cord Herbert, Coisne, C., Sixt, M., Wekerle, H., Engelhardt, B. & Fässler, R., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 6, p. 1920-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A function for Rac1 in the terminal differentiation and pigmentation of hair

    Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, Cord Herbert & Haase, I., 24 Jan 2012, In: Journal of Cell Science. 125, Pt 4, p. 896-905 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Pigmentation defect due to the deficiency of Rac1 in differentiated parts of the hair follicle

    Behrundt, K., Brakebusch, Cord Herbert, Pofahl, R., Krieg, T. & Hasse, I., 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.

    Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., Wu, X., Chrostek-Grashoff, A., Herzog, D., Nave, K., Franklin, R. J. M., Meijer, D., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2007, In: Journal of Cell Biology. 177, 6, p. 1051-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha.

    Bergmeier, W., Bouvard, D., Eble, J. A., Mokhtari-Nejad, R., Schulte, V., Zirngibl, H., Brakebusch, Cord Herbert, Fässler, R. & Nieswandt, B., 2001, In: Journal of Biological Chemistry. 276, 27, p. 25121-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

    Bigda, J., Beletsky, I., Brakebusch, Cord Herbert, Varfolomeev, Y., Engelmann, H., Bigda, J., Holtmann, H. & Wallach, D., 1994, In: Journal of Experimental Medicine. 180, 2, p. 445-60 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

    Bischoff, N., Wimberger, S., Maresca, M. & Brakebusch, Cord Herbert, 2020, In: Cells. 9, 5

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

    Blattner, S. M., Hodgin, J. B., Nishio, M., Wylie, S. A., Saha, J., Soofi, A. A., Vining, C., Randolph, A., Herbach, N., Wanke, R., Atkins, K. B., Gyung Kang, H., Henger, A., Brakebusch, Cord Herbert, Holzman, L. B. & Kretzler, M., 15 May 2013, In: Kidney International.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Beta 1 integrin is essential for teratoma growth and angiogenesis.

    Bloch, W., Forsberg, E., Lentini, S., Brakebusch, Cord Herbert, Martin, K., Krell, H. W., Weidle, U. H., Addicks, K. & Fässler, R., 1997, In: Journal of Cell Biology. 139, 1, p. 265-78 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    FMNL2 drives actin-based protrusion and migration downstream of Cdc42

    Block, J., Breitsprecher, D., Kühn, S., Winterhoff, M., Kage, F., Geffers, R., Duwe, P., Rohn, J. L., Baum, B., Brakebusch, Cord Herbert, Geyer, M., Stradal, T. E. B., Faix, J. & Rottner, K., 5 Jun 2012, In: Current Biology. 22, 11, p. 1005-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, eadi7840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose?

    Boehncke, W., Schön, M. P., Girolomoni, G., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2005, In: Experimental Dermatology. 14, 1, p. 70-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? (vol 14, pg 70, 2005)

    Boehncke, W. H., Schon, M. P., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2007, In: Experimental Dermatology. 16, 9, p. 778-778

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

    Bosse, T., Ehinger, J., Czuchra, A., Benesch, S., Steffen, A., Wu, X., Schloen, K., Niemann, H. H., Scita, G., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 2007, In: Molecular and Cellular Biology. 27, 19, p. 6615-28 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Functional consequences of integrin gene mutations in mice.

    Bouvard, D., Brakebusch, Cord Herbert, Gustafsson, E., Aszódi, A., Bengtsson, T., Berna, A. & Fässler, R., 2001, In: Circulation Research. 89, 3, p. 211-23 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

    Brakebusch, Cord Herbert, Nophar, Y., Kemper, O., Engelmann, H. & Wallach, D., 1992, In: EMBO Journal. 11, 3, p. 943-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.

    Brakebusch, Cord Herbert, Wennerberg, K., Krell, H. W., Weidle, U. H., Sallmyr, A., Johansson, S. & Fässler, R., 1999, In: Oncogene. 18, 26, p. 3852-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    beta 1 integrin function in vivo: adhesion, migration and more.

    Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules.

    Brakebusch, Cord Herbert, Hirsch, E., Potocnik, A. & Fässler, R., 1997, In: Journal of Cell Science. 110 ( Pt 23), p. 2895-904 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.

    Brakebusch, Cord Herbert, Grose, R., Quondamatteo, F., Ramirez, A., Jorcano, J. L., Pirro, A., Svensson, M., Herken, R., Sasaki, T., Timpl, R., Werner, S. & Fässler, R., 2000, In: EMBO Journal. 19, 15, p. 3990-4003 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Isolation and functional characterization of the human 90K promoter.

    Brakebusch, Cord Herbert, Sures, I., Jallal, B., Mossie, K., Fusco, O., Iacobelli, S. & Ullrich, A., 1999, In: Genomics. 57, 2, p. 268-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.

    Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.

    Brakebusch, Cord Herbert, Jallal, B., Fusco, O., Iacobelli, S. & Ullrich, A., 1997, In: Journal of Biological Chemistry. 272, 6, p. 3674-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory.

    Brakebusch, Cord Herbert, Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., Montag, D., Gundelfinger, E. D. & Fässler, R., 2002, In: Molecular and Cellular Biology. 22, 21, p. 7417-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The integrin-actin connection, an eternal love affair.

    Brakebusch, Cord Herbert & Fässler, R., 2003, In: EMBO Journal. 22, 10, p. 2324-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journal › Editorial › Research › peer-review

  36. Published

    Genetically Modified Mice in Medical and Pharmaceutical Research

    Brakebusch, Cord Herbert, 5 Feb 2008, Modern Biopharmaceuticals: Design, Development and Optimization. Wiley-VCH, Vol. 2. p. 649-660 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Integrin blockade as therapy in chronic inflammation

    Brakebusch, Cord Herbert, 1 May 2005, In: Experimental Dermatology. 14, 5, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  38. Keratinocyte Migration in Wound Healing

    Brakebusch, Cord Herbert, 9 Aug 2005, Cell Migration in Development and Disease. Wiley-VCH Verlag GmbH & Co. KGaA, p. 275-298 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  39. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journal › Editorial › Research › peer-review

  40. Published

    Integrins in invasive growth.

    Brakebusch, Cord Herbert, Bouvard, D., Stanchi, F., Sakai, T. & Fässler, R., 2002, In: Journal of Clinical Investigation. 109, 8, p. 999-1006 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response.

    Brakebusch, Cord Herbert, Fillatreau, S., Potocnik, A. J., Bungartz, G., Wilhelm, P., Svensson, M., Kearney, P., Körner, H., Gray, D. & Fässler, R., 2002, In: Immunity. 16, 3, p. 465-77 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Mouse as a Model Organism: From Animals to Cells

    Brakebusch, Cord Herbert (ed.) & Pihlajaniemi, T. (ed.), 2011, Dordrecht: Springer. 165 p.

    Research output: Book/Report › Anthology › Research › peer-review

  43. Published

    Generation and analysis of genetically modified mice

    Brakebusch, Cord Herbert, 2011, Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, J. & Schapiro, SJ. (eds.). 3rd ed. Boca Raton, London, New York: CRC Press, Vol. 1.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.

    Breau, M. A., Pietri, T., Eder, O., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. P. & Dufour, S., 2006, In: Development. 133, 9, p. 1725-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.

    Bungartz, G., Stiller, S., Bauer, M., Müller, W., Schippers, A., Wagner, N., Fässler, R. & Brakebusch, Cord Herbert, 2006, In: Blood. 108, 6, p. 1857-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity

    Burbage, M., Keppler, S. J., Gasparrini, F., Martínez-Martín, N., Gaya, M., Feest, C., Domart, M., Brakebusch, Cord Herbert, Collinson, L., Bruckbauer, A. & Batista, F. D., 2015, In: The Journal of Experimental Medicine. 212, 1, p. 53-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance.

    Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, Cord Herbert, Fässler, R., Suter, U. & ffrench-Constant, C., 2004, In: Development. 131, 14, p. 3433-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A radial glia-specific role of RhoA in double cortex formation

    Cappello, S., Böhringer, C. R. J., Bergami, M., Conzelmann, K., Ghanem, A., Tomassy, G. S., Arlotta, P., Mainardi, M., Allegra, M., Caleo, M., van Hengel, J., Brakebusch, Cord Herbert & Götz, M., 8 Mar 2012, In: Neuron. 73, 5, p. 911-24 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

    Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 5296