Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

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  1. Published

    Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

    Aderka, D., Engelmann, H., Maor, Y., Brakebusch, Cord Herbert & Wallach, D., 1992, In: Journal of Experimental Medicine. 175, 2, p. 323-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

    Akula, M. K., Ibrahim, M. X., Ivarsson, E. G., Khan, O. M., Kumar, I. T., Erlandsson, M., Karlsson, C., Xu, X., Brisslert, M., Brakebusch, Cord Herbert, Wang, D., Bokarewa, M., Sayin, V. I. & Bergo, M. O., 4 Sep 2019, In: Nature Communications. 10, 1, p. 1-13 13 p., 3975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.

    Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., Brandt, C., Löscher, W., Grimberg, D., Dresbach, T., Hempelmann, A., Hassan, H., Balschun, D., Frey, J. U., Brandstätter, J. H., Garner, C. C. & 2 others, Rosenmund, C. & Gundelfinger, E. D., 2003, In: Neuron. 37, 5, p. 787-800 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cytoskeletal stability in the auditory organ in vivo: RhoA is dispensable for wound healing but essential for hair cell development

    Anttonen, T., Belevich, I., Laos, M., Herranen, A., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2017, In: eNeuro. 4, 5, 17 p., e0149-17.2017.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    How to Bury the Dead: Elimination of Apoptotic Hair Cells from the Hearing Organ of the Mouse

    Anttonen, T., Belevich, I., Kirjavainen, A., Laos, M., Brakebusch, Cord Herbert, Jokitalo, E. & Pirvola, U., 30 Jul 2014, In: J A R O. 15, 6, p. 975-992 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood

    Anttonen, T., Kirjavainen, A., Belevich, I., Laos, M., Richardson, W. D., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2012, In: Scientific Reports. 2, p. 978

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

    Aszodi, A., Hunziker, E. B., Brakebusch, Cord Herbert & Fässler, R., 2003, In: Genes & Development. 17, 19, p. 2465-79 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Opposing roles for RhoH GTPase during T-cell migration and activation

    Baker, C. M., Comrie, W. A., Hyun, Y., Chung, H., Fedorchuk, C. A., Lim, K., Brakebusch, Cord Herbert, McGrath, J. L., Waugh, R. E., Meier-Schellersheim, M. & Kim, M., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. 10474-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity

    Bauer, M., Brakebusch, Cord Herbert, Coisne, C., Sixt, M., Wekerle, H., Engelhardt, B. & Fässler, R., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 6, p. 1920-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A function for Rac1 in the terminal differentiation and pigmentation of hair

    Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, Cord Herbert & Haase, I., 24 Jan 2012, In: Journal of Cell Science. 125, Pt 4, p. 896-905 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Pigmentation defect due to the deficiency of Rac1 in differentiated parts of the hair follicle

    Behrundt, K., Brakebusch, Cord Herbert, Pofahl, R., Krieg, T. & Hasse, I., 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.

    Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., Wu, X., Chrostek-Grashoff, A., Herzog, D., Nave, K., Franklin, R. J. M., Meijer, D., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2007, In: Journal of Cell Biology. 177, 6, p. 1051-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha.

    Bergmeier, W., Bouvard, D., Eble, J. A., Mokhtari-Nejad, R., Schulte, V., Zirngibl, H., Brakebusch, Cord Herbert, Fässler, R. & Nieswandt, B., 2001, In: Journal of Biological Chemistry. 276, 27, p. 25121-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

    Bigda, J., Beletsky, I., Brakebusch, Cord Herbert, Varfolomeev, Y., Engelmann, H., Bigda, J., Holtmann, H. & Wallach, D., 1994, In: Journal of Experimental Medicine. 180, 2, p. 445-60 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

    Bischoff, N., Wimberger, S., Maresca, M. & Brakebusch, Cord Herbert, 2020, In: Cells. 9, 5

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

    Blattner, S. M., Hodgin, J. B., Nishio, M., Wylie, S. A., Saha, J., Soofi, A. A., Vining, C., Randolph, A., Herbach, N., Wanke, R., Atkins, K. B., Gyung Kang, H., Henger, A., Brakebusch, Cord Herbert, Holzman, L. B. & Kretzler, M., 15 May 2013, In: Kidney International.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Beta 1 integrin is essential for teratoma growth and angiogenesis.

    Bloch, W., Forsberg, E., Lentini, S., Brakebusch, Cord Herbert, Martin, K., Krell, H. W., Weidle, U. H., Addicks, K. & Fässler, R., 1997, In: Journal of Cell Biology. 139, 1, p. 265-78 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    FMNL2 drives actin-based protrusion and migration downstream of Cdc42

    Block, J., Breitsprecher, D., Kühn, S., Winterhoff, M., Kage, F., Geffers, R., Duwe, P., Rohn, J. L., Baum, B., Brakebusch, Cord Herbert, Geyer, M., Stradal, T. E. B., Faix, J. & Rottner, K., 5 Jun 2012, In: Current Biology. 22, 11, p. 1005-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, eadi7840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose?

    Boehncke, W., Schön, M. P., Girolomoni, G., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2005, In: Experimental Dermatology. 14, 1, p. 70-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? (vol 14, pg 70, 2005)

    Boehncke, W. H., Schon, M. P., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2007, In: Experimental Dermatology. 16, 9, p. 778-778

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

    Bosse, T., Ehinger, J., Czuchra, A., Benesch, S., Steffen, A., Wu, X., Schloen, K., Niemann, H. H., Scita, G., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 2007, In: Molecular and Cellular Biology. 27, 19, p. 6615-28 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Functional consequences of integrin gene mutations in mice.

    Bouvard, D., Brakebusch, Cord Herbert, Gustafsson, E., Aszódi, A., Bengtsson, T., Berna, A. & Fässler, R., 2001, In: Circulation Research. 89, 3, p. 211-23 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

    Brakebusch, Cord Herbert, Nophar, Y., Kemper, O., Engelmann, H. & Wallach, D., 1992, In: EMBO Journal. 11, 3, p. 943-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.

    Brakebusch, Cord Herbert, Wennerberg, K., Krell, H. W., Weidle, U. H., Sallmyr, A., Johansson, S. & Fässler, R., 1999, In: Oncogene. 18, 26, p. 3852-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    beta 1 integrin function in vivo: adhesion, migration and more.

    Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules.

    Brakebusch, Cord Herbert, Hirsch, E., Potocnik, A. & Fässler, R., 1997, In: Journal of Cell Science. 110 ( Pt 23), p. 2895-904 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.

    Brakebusch, Cord Herbert, Grose, R., Quondamatteo, F., Ramirez, A., Jorcano, J. L., Pirro, A., Svensson, M., Herken, R., Sasaki, T., Timpl, R., Werner, S. & Fässler, R., 2000, In: EMBO Journal. 19, 15, p. 3990-4003 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Isolation and functional characterization of the human 90K promoter.

    Brakebusch, Cord Herbert, Sures, I., Jallal, B., Mossie, K., Fusco, O., Iacobelli, S. & Ullrich, A., 1999, In: Genomics. 57, 2, p. 268-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.

    Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.

    Brakebusch, Cord Herbert, Jallal, B., Fusco, O., Iacobelli, S. & Ullrich, A., 1997, In: Journal of Biological Chemistry. 272, 6, p. 3674-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory.

    Brakebusch, Cord Herbert, Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., Montag, D., Gundelfinger, E. D. & Fässler, R., 2002, In: Molecular and Cellular Biology. 22, 21, p. 7417-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The integrin-actin connection, an eternal love affair.

    Brakebusch, Cord Herbert & Fässler, R., 2003, In: EMBO Journal. 22, 10, p. 2324-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journal › Editorial › Research › peer-review

  36. Published

    Genetically Modified Mice in Medical and Pharmaceutical Research

    Brakebusch, Cord Herbert, 5 Feb 2008, Modern Biopharmaceuticals: Design, Development and Optimization. Wiley-VCH, Vol. 2. p. 649-660 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Integrin blockade as therapy in chronic inflammation

    Brakebusch, Cord Herbert, 1 May 2005, In: Experimental Dermatology. 14, 5, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  38. Keratinocyte Migration in Wound Healing

    Brakebusch, Cord Herbert, 9 Aug 2005, Cell Migration in Development and Disease. Wiley-VCH Verlag GmbH & Co. KGaA, p. 275-298 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  39. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journal › Editorial › Research › peer-review

  40. Published

    Integrins in invasive growth.

    Brakebusch, Cord Herbert, Bouvard, D., Stanchi, F., Sakai, T. & Fässler, R., 2002, In: Journal of Clinical Investigation. 109, 8, p. 999-1006 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response.

    Brakebusch, Cord Herbert, Fillatreau, S., Potocnik, A. J., Bungartz, G., Wilhelm, P., Svensson, M., Kearney, P., Körner, H., Gray, D. & Fässler, R., 2002, In: Immunity. 16, 3, p. 465-77 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Mouse as a Model Organism: From Animals to Cells

    Brakebusch, Cord Herbert (ed.) & Pihlajaniemi, T. (ed.), 2011, Dordrecht: Springer. 165 p.

    Research output: Book/Report › Anthology › Research › peer-review

  43. Published

    Generation and analysis of genetically modified mice

    Brakebusch, Cord Herbert, 2011, Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, J. & Schapiro, SJ. (eds.). 3rd ed. Boca Raton, London, New York: CRC Press, Vol. 1.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.

    Breau, M. A., Pietri, T., Eder, O., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. P. & Dufour, S., 2006, In: Development. 133, 9, p. 1725-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.

    Bungartz, G., Stiller, S., Bauer, M., Müller, W., Schippers, A., Wagner, N., Fässler, R. & Brakebusch, Cord Herbert, 2006, In: Blood. 108, 6, p. 1857-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity

    Burbage, M., Keppler, S. J., Gasparrini, F., Martínez-Martín, N., Gaya, M., Feest, C., Domart, M., Brakebusch, Cord Herbert, Collinson, L., Bruckbauer, A. & Batista, F. D., 2015, In: The Journal of Experimental Medicine. 212, 1, p. 53-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance.

    Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, Cord Herbert, Fässler, R., Suter, U. & ffrench-Constant, C., 2004, In: Development. 131, 14, p. 3433-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A radial glia-specific role of RhoA in double cortex formation

    Cappello, S., Böhringer, C. R. J., Bergami, M., Conzelmann, K., Ghanem, A., Tomassy, G. S., Arlotta, P., Mainardi, M., Allegra, M., Caleo, M., van Hengel, J., Brakebusch, Cord Herbert & Götz, M., 8 Mar 2012, In: Neuron. 73, 5, p. 911-24 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

    Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression

    Castro, M., Laviña, B., Ando, K., Álvarez-Aznar, A., Abu Taha, A., Brakebusch, Cord Herbert, Dejana, E., Betsholtz, C. & Gaengel, K. B., 2019, In: Circulation Research. 124, 8, p. 1240-1252 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

    Cavaco, A. C. M., Rezaei, M., Caliandro, M. F., Lima, A. M., Stehling, M., Dhayat, S. A., Haier, J., Brakebusch, Cord Herbert & Eble, J. A., 2019, In: Cancers. 11, 1, p. 1-20 20 p., 14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation.

    Chidgey, M., Brakebusch, Cord Herbert, Gustafsson, E., Cruchley, A., Hail, C., Kirk, S., Merritt, A., North, A., Tselepis, C., Hewitt, J., Byrne, C., Fassler, R. & Garrod, D., 2001, In: Journal of Cell Biology. 155, 5, p. 821-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice

    Choudhari, R., Minero, V. G., Menotti, M., Pulito, R., Brakebusch, Cord Herbert, Compagno, M., Voena, C., Ambrogio, C. & Chiarle, R., 10 Mar 2016, In: Blood. 127, 10, p. 1297-306 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.

    Chrostek, A., Wu, X., Quondamatteo, F., Hu, R., Sanecka, A., Niemann, C., Langbein, L., Haase, I. & Brakebusch, Cord Herbert, 2006, In: Molecular and Cellular Biology. 26, 18, p. 6957-70 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.

    Cordes, N., Seidler, J., Durzok, R., Geinitz, H. & Brakebusch, Cord Herbert, 2006, In: Oncogene. 25, 9, p. 1378-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.

    Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K. & Brakebusch, Cord Herbert, 2005, In: Molecular Biology of the Cell. 16, 10, p. 4473-84 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Genetic analysis of beta1 integrin "activation motifs" in mice.

    Czuchra, A., Meyer, H., Legate, K. R., Brakebusch, Cord Herbert & Fässler, R., 2006, In: Journal of Cell Biology. 174, 6, p. 889-99 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

    Danen, E. H. J., Sonneveld, P., Brakebusch, Cord Herbert, Fassler, R. & Sonnenberg, A., 2002, In: Journal of Cell Biology. 159, 6, p. 1071-86 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.

    Dixon, J., Brakebusch, Cord Herbert, Fässler, R. & Dixon, M. J., 2000, In: Human Molecular Genetics. 9, 10, p. 1473-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    RhoH is important for positive thymocyte selection and T-cell receptor signaling.

    Dorn, T., Kuhn, U., Bungartz, G., Stiller, S., Bauer, M., Ellwart, J., Peters, T., Scharffetter-Kochanek, K., Semmrich, M., Laschinger, M., Holzmann, B., Klinkert, W. E. F., Straten, P. T., Køllgaard, T., Sixt, M. & Brakebusch, Cord Herbert, 2006, In: Blood. 109, 6, p. 2346-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Cdc42 is crucial for the maturation of primordial cell junctions in keratinocytes independent of Rac1

    Du, D., Pedersen, E., Wang, Z., Karlsson, R., Chen, Z., Wu, X. & Brakebusch, Cord Herbert, 2008, In: Experimental Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    RhoA Controls Axon Extension Independent of Specification in the Developing Brain

    Dupraz, S., Hilton, B. J., Husch, A., Santos, T. E., Coles, C. H., Stern, S., Brakebusch, Cord Herbert & Bradke, F., 18 Nov 2019, In: Current biology : CB. 29, 22, p. 3874-3886 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

    Dütting, S., Gaits-Iacovoni, F., Stegner, D., Popp, M., Antkowiak, A., Van Eeuwijk, J. M. M., Nurden, P., Stritt, S., Heib, T., Aurbach, K., Angay, O., Cherpokova, D., Heinz, N., Baig, A. A., Gorelashvili, M. G., Gerner, F., Heinze, K. G., Ware, J., Krohne, G., Ruggeri, Z. M. & 6 others, Nurden, A. T., Schulze, H., Modlich, U., Pleines, I., Brakebusch, Cord Herbert & Nieswandt, B., 15 Jun 2017, In: Nature Communications. 8, 13 p., 15838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets

    Dütting, S., Heidenreich, J., Cherpokova, D., Amin, E., Zhang, S., Ahmadian, M. R., Brakebusch, Cord Herbert & Nieswandt, B., May 2015, In: Journal of Thrombosis and Haemostasis. 13, 5, p. 827-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development

    Elias, B. C., Das, A., Parekh, D. V., Mernaugh, G., Adams, R., Yang, Z., Brakebusch, Cord Herbert, Pozzi, A., Marciano, D. K., Carroll, T. J. & Zent, R., 1 Dec 2015, In: Journal of Cell Science. 128, 23, p. 4293-305 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

    Engelmann, H., Holtmann, H., Brakebusch, Cord Herbert, Avni, Y. S., Sarov, I., Nophar, Y., Hadas, E., Leitner, O. & Wallach, D., 1990, In: Journal of Biological Chemistry. 265, 24, p. 14497-504 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1

    Fuchs, S., Herzog, D., Sumara, G., Büchmann-Møller, S., Civenni, G., Wu, X., Chrostek-Grashoff, A., Suter, U., Ricci, R., Relvas, J. B., Brakebusch, Cord Herbert & Sommer, L., 2009, In: Cell Stem Cell. 4, 3, p. 236-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.

    Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

    García-Mariscal, A., Li, H., Pedersen, E., Peyrollier, K., Ryan, K. M., Stanley, A., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Feb 2018, In: Oncogene. 37, 7, p. 847-860 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    RhoA Controls Retinoid Signaling by ROCK Dependent Regulation of Retinol Metabolism

    García-Mariscal, A., Peyrollier, K., Basse, A., Pedersen, E. D. K., Rühl, R., van Hengel, J. & Brakebusch, Cord Herbert, 2018, In: Small GTPases. 9, 5, p. 433–444

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Cdc42 regulates cofilin during the establishment of neuronal polarity.

    Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, Cord Herbert, Bamburg, J. R. & Bradke, F., 2007, In: Journal of Neuroscience. 27, 48, p. 13117-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells

    Ge, J., Burnier, L., Adamopoulou, M., Kwa, M. Q., Schaks, M., Rottner, K. & Brakebusch, Cord Herbert, 2018, In: The Journal of Biological Chemistry. 293, 24, p. 9358-9369 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

    Gilles, G., McCulloch, A. D., Brakebusch, Cord Herbert & Herum, K. M., 2020, In: PLoS ONE. 15, 10, p. 1-13 e0241390.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.

    Gimond, C., van Der Flier, A., van Delft, S., Brakebusch, Cord Herbert, Kuikman, I., Collard, J. G., Fässler, R. & Sonnenberg, A., 1999, In: Journal of Cell Biology. 147, 6, p. 1325-40 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair.

    Grose, R., Hutter, C., Bloch, W., Thorey, I., Watt, F. M., Fässler, R., Brakebusch, Cord Herbert & Werner, S., 2002, In: Development. 129, 9, p. 2303-15 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

    Grüner, S., Prostredna, M., Schulte, V., Krieg, T., Eckes, B., Brakebusch, Cord Herbert & Nieswandt, B., 2003, In: Blood. 102, 12, p. 4021-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.

    Gustafsson, E., Brakebusch, Cord Herbert, Hietanen, K. & Fässler, R., 2001, In: Journal of Cell Science. 114, Pt 4, p. 671-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Role of the beta1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia.

    Gustavsson, A., Armulik, A., Brakebusch, Cord Herbert, Fässler, R., Johansson, S. & Fällman, M., 2002, In: Journal of Cell Science. 115, Pt 13, p. 2669-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Functions of Rac1 in the epidermis

    Haase, I. & Brakebusch, Cord Herbert, 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

    Haditsch, U., Leone, D. P., Farinelli, M., Chrostek-Grashoff, A., Brakebusch, Cord Herbert, Mansuy, I. M., McConnell, S. K. & Palmer, T. D., 2009, In: Molecular and Cellular Neuroscience. 41, 4, p. 409-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Neuronal Rac1 is required for learning-evoked neurogenesis

    Haditsch, U., Anderson, M. P., Freewoman, J., Cord, B., Babu, H., Brakebusch, Cord Herbert & Palmer, T. D., 24 Jul 2013, In: Journal of Neuroscience. 33, 30, p. 12229-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Rac1 is essential for basement membrane-dependent epiblast survival

    He, X., Liu, J., Qi, Y., Brakebusch, Cord Herbert, Chrostek-Grashoff, A., Edgar, D., Yurchenco, P. D., Corbett, S. A., Lowry, S. F., Graham, A. M., Han, Y. & Li, S., 2010, In: Molecular and Cellular Biology. 30, 14, p. 3569-81 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.

    He, Z., Brakebusch, Cord Herbert, Fässler, R., Kreidberg, J. A., Primakoff, P. & Myles, D. G., 2003, In: Developmental Biology. 254, 2, p. 226-37 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

    Heib, T., Hermanns, H. M., Manukjan, G., Englert, M., Kusch, C., Becker, I. C., Gerber, A., Wackerbarth, L. M., Burkard, P., Dandekar, T., Balkenhol, J., Jahn, D., Beck, S., Meub, M., Dütting, S., Stigloher, C., Sauer, M., Cherpokova, D., Schulze, H., Brakebusch, C. & 3 others, Nieswandt, B., Nagy, Z. & Pleines, I., 2021, In: Cell Reports. 35, 6, p. 109102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Hepatocyte dysplasia and tumor nodule formation in CDC42-deficient mouse liver

    Hengel, J. V., D'Hooge, P., Wu, X. W., Libbrecht, L., Vos, R. D., Brakebusch, Cord Herbert & Roy, F. V., 2008, In: Acta Clinica Belgica. 63, 1, p. 56-56

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Distinct roles for dystroglycan, beta1 integrin and perlecan in cell surface laminin organization.

    Henry, M. D., Satz, J. S., Brakebusch, Cord Herbert, Costell, M., Gustafsson, E., Fässler, R. & Campbell, K. P., 2001, In: Journal of Cell Science. 114, Pt 6, p. 1137-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

    Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, Cord Herbert, McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020, In: Journal of the American Heart Association. 9, 3, 31 p., e013518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo

    Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool

    Herzog, D., Loetscher, P., van Hengel, J., Knüsel, S., Brakebusch, Cord Herbert, Taylor, V., Suter, U. & Relvas, J. B., 30 Mar 2011, In: Journal of Neuroscience. 31, 13, p. 5120-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Mechanisms controlling the level of receptors for tumor necrosis factor.

    Holtmann, H., Brakebusch, Cord Herbert, König, M., Klocke, R., Winzen, R., Resch, K. & Wallach, D., 1991, In: Agents and Actions. 32, 1-2, p. 106-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1

    Huelsenbeck, S. C., Roggenkamp, D., May, M., Huelsenbeck, J., Brakebusch, Cord Herbert, Rottner, K., Ladwein, M., Just, I., Fritz, G., Schmidt, G. & Genth, H., Aug 2013, In: International Journal of Biochemistry & Cell Biology. 45, 8, p. 1767-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.

    Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

    Jackson, B., Peyrollier, K., Pedersen, E., Basse, A., Karlsson, R., Wang, Z., Lefever, T., Ochsenbein, A. M., Schmidt, G., Aktories, K., Stanley, A., Quondamatteo, F., Ladwein, M., Rottner, K., van Hengel, J. & Brakebusch, Cord Herbert, 1 Mar 2011, In: Molecular Biology of the Cell. 22, 5, p. 593-605 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Suppression of tumor growth in vivo by local and systemic 90K level increase.

    Jallal, B., Powell, J., Zachwieja, J., Brakebusch, Cord Herbert, Germain, L., Jacobs, J., Iacobelli, S. & Ullrich, A., 1995, In: Cancer Research. 55, 15, p. 3223-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

    Jennings, R. T., Strengert, M., Hayes, P., El-Benna, J., Brakebusch, Cord Herbert, Kubica, M. & Knaus, U. G., 29 Apr 2014, In: Blood. 123, 23, p. 3635-45 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    FMNL formins boost lamellipodial force generation

    Kage, F., Winterhoff, M., Dimchev, V., Mueller, J., Thalheim, T., Freise, A., Brühmann, S., Kollasser, J., Block, J., Dimchev, G. A., Geyer, M., Schnittler, H., Brakebusch, Cord Herbert, Stradal, T. E. B., Carlier, M., Sixt, M., Käs, J., Faix, J. & Rottner, K., 22 Mar 2017, In: Nature Communications. 8, 16 p., 14832.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 26 Nov 2019, In: Scientific Reports. 9, 1, p. 18008 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  100. Published

    FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 17 p., 9791.

    Research output: Contribution to journal › Journal article › Research › peer-review

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