Børge Nordestgaard

Børge Nordestgaard

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2018
  2. Published

    Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

    Went, M., Sud, A., Försti, A., Halvarsson, B. M., Weinhold, N., Kimber, S., van Duin, M., Thorleifsson, G., Holroyd, A., Johnson, D. C., Li, N., Orlando, G., Law, P. J., Ali, M., Chen, B., Mitchell, J. S., Gudbjartsson, D. F., Kuiper, R., Stephens, O. W., Bertsch, U. & 31 others, Broderick, P., Campo, C., Bandapalli, O. R., Einsele, H., Gregory, W. A., Gullberg, U., Hillengass, J., Hoffmann, P., Jackson, G. H., Jöckel, K. H., Johnsson, E., Kristinsson, S. Y., Mellqvist, U. H., Nahi, H., Easton, D., Pharoah, P., Dunning, A., Peto, J., Canzian, F., Swerdlow, A., Eeles, R. A., Kote-Jarai, Z. S., Muir, K., Pashayan, N., Nickel, J., Nöthen, M. M., Vangsted, Annette Juul, Andersen, N. F., Nilsson, B., Nordestgaard, Børge & The Practical Consortium, T. P. C., 13 Sep 2018, In: Nature Communications. 9, 10 p., 3707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Relationship of Familial Hypercholesterolemia and High Low-Density Lipoprotein Cholesterol to Ischemic Stroke: Copenhagen General Population Study

    Beheshti, S., Madsen, C. M., Varbo, A., Benn, Marianne & Nordestgaard, Børge, Aug 2018, In: Circulation. 138, 6, p. 578-589 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment

    Benn, Marianne & Nordestgaard, Børge, 15 Jul 2018, In: Cardiovascular Research. 114, 9, p. 1192-1208 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Complement C3 and Risk of Diabetic Microvascular Disease: A Cohort Study of 95202 Individuals from the General Population

    Rasmussen, K. L., Nordestgaard, Børge & Nielsen, S. F., Jul 2018, In: Clinical Chemistry. 64, 7, p. 1113-1124 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM

    European Atherosclerosis Society (EAS) and the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Joint Consensus Initiative, E. A. S. (. A. T. E. F. O. C. C. A. L. M. (. J. C. I., Jul 2018, In: Clinical Chemistry. 64, 7, p. 1006-1033 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block

    Skov, M. W., Ghouse, J., Kühl, J. T., Platonov, P. G., Graff, C., Fuchs, A., Rasmussen, P. V., Pietersen, A., Nordestgaard, Børge, Torp-Pedersen, C., Hansen, S. M., Olesen, Morten Steen Salling, Haunsø, Stig, Køber, Lars Valeur, Gerds, Thomas Alexander, Kofoed, Klaus Fuglsang, Svendsen, Jesper Hastrup, Holst, A. G. & Nielsen, J. B., 5 Jun 2018, In: Journal of the American Heart Association. 7, 11, 19 p., e008247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

    Wood, A. M., Nordestgaard, Børge, Dahm, C. C., Linneberg, Allan René, Overvad, K., Tjønneland, Anne & Emerging Risk Factors Collaboration/EPIC-CVD/UK Biobank Alcohol Study Group, E. R. F. C. B. A. S. G., 14 Apr 2018, In: The Lancet. 391, 10129, p. 1513-1523 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, Flannick, J., Grarup, Niels, Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, Shoaib, Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Lactase persistence, milk intake, and mortality in the Danish general population: a Mendelian randomization study

    Bergholdt, H. K. M., Nordestgaard, Børge, Varbo, A. & Ellervik, Christina, 1 Feb 2018, In: European Journal of Epidemiology. 33, 2, p. 171–181

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The year in cardiology 2017: prevention

    Nordestgaard, Børge, Cosentino, F., Landmesser, U. & Laufs, U., 1 Feb 2018, In: European Heart Journal. 39, 5, p. 345-353

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ABCA7 and risk of dementia and vascular disease in the Danish population

    Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals

    Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

    Wu, L., Shi, W., Long, J., Guo, X., Michailidou, K., Beesley, J., Bolla, M. K., Shu, X-O., Lu, Y., Cai, Q., Al-Ejeh, F., Rozali, E., Wang, Q., Dennis, J., Li, B., Zeng, C., Feng, H., Gusev, A., Barfield, R. T., Andrulis, I. L. & 31 others, Anton-Culver, H., Arndt, V., Aronson, K. J., Auer, P. L., Barrdahl, M., Baynes, C., Beckmann, M. W., Benitez, J., Bermisheva, M., Blomqvist, C., Bogdanova, N. V., Bojesen, Stig Egil, Brauch, H., Brenner, H., Brinton, L., Broberg, P., Brucker, S. Y., Burwinkel, B., Caldés, T., Canzian, F., Carter, B. D., Castelao, J. E., Chang-Claude, J., Chen, X., Cheng, T. D., Christiansen, H., Clarke, C. L., Flyger, H., Nielsen, S. F., Nordestgaard, Børge & NBCS Collaborators, N. C., 2018, In: Nature Genetics. 50, 7, p. 968-978 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    AA9int: SNP interaction pattern search using non-hierarchical additive model set

    PRACTICAL consortium, P. C., 2018, In: Bioinformatics. 34, 24, p. 4141-4150 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    AHRR hypomethylation, lung function, lung function decline and respiratory symptoms

    Kodal, J. B., Kobylecki, C. J., Vedel-Krogh, S., Nordestgaard, Børge & Bojesen, Stig Egil, 2018, In: The European Respiratory Journal. 51, 3, 1701512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Absolute 10-year risk of dementia by age, sex and APOE genotype: A population-based cohort study

    Rasmussen, K. L., Tybjarg-Hansen, A., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: CMAJ. 190, 35, p. E1033-E1041

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Advances in lipid-lowering therapy through gene-silencing technologies

    Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract

    European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2018, In: European Heart Journal. 39, 27, p. 2526-2539 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Airflow limitation in people living with HIV and matched uninfected controls

    Ronit, A., Lundgren, Jens, Afzal, Shoaib, Benfield, Thomas, Roen, A., Mocroft, A., Gerstoft, Jan, Nordestgaard, Børge, Vestbo, J., Nielsen, S. D. & Copenhagen Co-morbidity in HIV infection (COCOMO) study group, C. C. I. H. I. (. S. G., 2018, In: Thorax. 73, 5, p. 431-438

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Alcohol Intake and Risk of Ischemic and Haemorrhagic Stroke: Results from a Mendelian Randomisation Study

    Christensen, A. I., Nordestgaard, Børge & Tolstrup, J. S., 2018, In: Journal of Stroke. 20, 2, p. 218-227

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    An updated Alzheimer hypothesis: Complement C3 and risk of Alzheimer's disease-A cohort study of 95,442 individuals

    Rasmussen, K. L., Nordestgaard, Børge, Frikke-Schmidt, Ruth & Nielsen, S. F., 2018, In: Alzheimer's & Dementia. 14, 12, p. 1589-1601 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Schumacher, F. R., Al Olama, A. A., Berndt, S. I., Sorensen, K. D., Orntoft, T. F., Borre, M., Nordestgaard, Børge, Røder, Andreas, Iversen, P., Australian Prostate Cancer BioResource, A. P. C. B., The IMPACT Study, T. I. S., Canary PASS Investigators, C. P. I., Breast and Prostate Cancer Cohort Consortium (BPC3), B. A. P. C. C. C. (., The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, T. P. (. C. A. G. T. I. C. A. I. T. G. C., Cancer of the Prostate in Sweden (CAPS), C. O. T. P. I. S. (., Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS), P. C. G. A. S. O. U. S. L. (., The Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium, T. G. A. A. M. I. O. (. L. I. I. P. C. S. (. C., Kote-Jarai, Z., Haiman, C. A. & Eeles, R. A., 2018, In: Nature Genetics. 50, p. 928-936

    Research output: Contribution to journalLetterResearchpeer-review

  26. Published

    Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

    European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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