Børge Nordestgaard

Børge Nordestgaard

Clinical Professor

Member of:

  • Clinical Biochemistry


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  1. Published

    Genetic variation in solute carrier family 5 member 2 mimicking sodium-glucose co-transporter 2-inhibition and risk of cardiovascular disease and all-cause mortality: reduced risk not explained by lower plasma glucose

    Bechmann, L. E., Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2023, In: Cardiovascular Research. 119, 14, p. 2482-2493 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Accepted/In press

    SGLT2-inhibition increases total, LDL, and HDL cholesterol and lowers triglycerides: Meta-analyses of 60 randomized trials, overall and by dose, ethnicity, and drug type

    Bechmann, L. E., Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2024, (Accepted/In press) In: Atherosclerosis. 117236.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Relationship of Familial Hypercholesterolemia and High Low-Density Lipoprotein Cholesterol to Ischemic Stroke: Copenhagen General Population Study

    Beheshti, S., Madsen, C. M., Varbo, A., Benn, Marianne & Nordestgaard, Børge, Aug 2018, In: Circulation. 138, 6, p. 578-589 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    How To Identify Familial Premature Myocardial Infarction: Comparing Approaches To Identify Familial Hypercholesterolemia

    Beheshti, S., Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2657-2667

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Worldwide Prevalence of Familial Hypercholesterolemia: Meta-Analyses of 11 Million Subjects

    Beheshti, S. O., Madsen, C. M., Varbo, A. & Nordestgaard, Børge, 2020, In: Journal of the American College of Cardiology. 75, 20, p. 2553-2566 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans

    Bejar, C. A., Goyal, S., Afzal, S., Mangino, M., Zhou, A., van der Most, P. J., Bao, Y., Gupta, V., Smart, M. C., Walia, G. K., Verweij, N., Power, C., Prabhakaran, D., Singh, J. R., Mehra, N. K., Wander, G. S., Ralhan, S., Kinra, S., Kumari, M., de Borst, M. H. & 5 others, Hyppönen, E., Spector, T. D., Nordestgaard, Børge, Blackett, P. R. & Sanghera, D. K., 2021, In: Nutrition Journal. 20, 1, p. 1-11 71.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    New insights into the genetic etiology of Alzheimer's disease and related dementias

    Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., Holmans, P. A., Boland, A., Damotte, V., van der Lee, S. J., Costa, M. R., Kuulasmaa, T., Yang, Q., de Rojas, I., Bis, J. C., Yaqub, A. & 39 others, Prokic, I., Chapuis, J., Ahmad, S., Giedraitis, V., Aarsland, D., Garcia-Gonzalez, P., Abdelnour, C., Alarcón-Martín, E., Alcolea, D., Alegret, M., Alvarez, I., Álvarez, V., Armstrong, N. J., Tsolaki, A., Antúnez, C., Appollonio, I., Arcaro, M., Archetti, S., Pastor, A. A., Arosio, B., Athanasiu, L., Bailly, H., Banaj, N., Baquero, M., Barral, S., Beiser, A., Nielsen, S. F., Nordestgaard, Børge, Sáez, M. E., Frikke-Schmidt, Ruth, EADB, E., GR@ACE, G., DEGESCO, D., EADI, E., GERAD, G., Demgene, D., FinnGen, F., ADGC, A. & CHARGE, C., 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study

    Benfield, T., Ejrnæs, K., Juul, K., Ostergaard, C., Helweg-Larsen, J., Weis, N., Munthe-Fog, L., Kronborg, G., Andersen, M. R., Tybjærg-Hansen, A., Nordestgaard, B. G., Garred, P., Benfield, T., Ejrnaes, K., Juul, K., Andersen, C. Ø., Helweg-Larsen, J., Weis, N. M., Munthe-Fog, L., Kronborg, G. & 4 others, Andersen, M. R., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Garred, Peter, 1 Jan 2010, In: Critical Care (Online Edition). 14, 2, p. R28

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study

    Benn, M., Nordestgaard, B., Jensen, G. B., Tybjaerg-Hansen, A., Tybjærg-Hansen, Anne, Benn, M. & Nordestgaard, Børge, 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 3, p. 661-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Common and rare alleles in apolipoprotein B contribute to plasma levels of low-density lipoprotein cholesterol in the general population

    Benn, Marianne, Stene, M. C. A., Nordestgaard, Børge, Jensen, G. B., Steffensen, R. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-1045 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment

    Benn, Marianne & Nordestgaard, Børge, 15 Jul 2018, In: Cardiovascular Research. 114, 9, p. 1192-1208 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study

    Benn, M., Tybjærg-Hansen, Anne, McCarthy, M. I., Jensen, G. B., Grande, P. & Nordestgaard, Børge, 2012, In: Journal of the American College of Cardiology. 59, 25, p. 2356-65 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Mitochondrial haplogroups: ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population

    Benn, M., Schwartz, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2008, In: Circulation. 117, 19, p. 2492-501 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Polymorphism in APOB associated with increased low-density lipoprotein levels in both genders in the general population

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Grande, P., Sillesen, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 10, p. 5797-803 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis

    Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    High body mass index and cancer risk

    Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study

    Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 3956-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals

    Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Nilausen, K. S., Meinertz, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Biological Chemistry. 280, 22, p. 21052-60 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality

    Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Polymorphisms in apolipoprotein B and risk of ischemic stroke

    Benn, M., Nordestgaard, Børge, Jensen, J. S. & Tybjærg-Hansen, Anne, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 9, p. 3611-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women

    Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses

    Benn, Marianne, Nordestgaard, Børge, Grande, P., Schnohr, P., Tybjærg-Hansen, Anne & Benn, M., 22 Jun 2010, In: Journal of the American College of Cardiology. 55, 25, p. 2833-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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