Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

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  1. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.

    Long, K. S. & Porse, Bo Torben, 2003, In: Nucleic Acids Research. 31, 24, p. 7208-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA

    Andersen, T., Porse, Bo Torben & Kirpekar, F., 1 Jun 2004, In: RNA. 10, 6, p. 907-913 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, Bo Torben, Enright, A. J. & O'Carroll, D., 2019, In: Cell Research. p. 221–232

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A sparsomycin-resistant mutant of Halobacterium salinarium lacks a modification at nucleotide U2603 in the peptidyl transferase centre of 23 S rRNA

    Lázaro, E., Rodriguez-Fonseca, C., Porse, Bo Torben, Ureña, D., Garrett, Roger Antony & Ballesta, J. P. G., 16 Aug 1996, In: Journal of Molecular Biology. 261, 2, p. 231-238 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

    Kirstetter, P., Anderson, K., Porse, Bo Torben, Jacobsen, S. E. W. & Nerlov, C., 2006, In: Nature Immunology. 7, 10, p. 1048-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

    Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

    Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Waage, J., Vitting-Seerup, K. & Porse, Bo Torben, 2015, In: BMC Genomics. 16, p. 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Antibiotic inhibition of the movement of tRNA substrates through a peptidyl transferase cavity.

    Porse, Bo Torben, Rodriguez-Fonseca, C., Leviev, I. & Garrett, R. A., 1996, In: Biochemistry and Cell Biology. 73, 11-12, p. 877-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Assembly of proteins and 5S rRNA to transcripts of the major structural domains of 23S rRNA

    Østergaard, P., Phan, H., Johansen, L. B., Egebjerg, J., Østergaard, L., Porse, Bo Torben & Garrett, Roger Antony, 1 Nov 1998, In: Journal of Molecular Biology. 284, 2, p. 227-240 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    BLUEPRINT to decode the epigenetic signature written in blood

    Adams, D., Altucci, L., Antonarakis, S. E., Ballesteros, J., Beck, S., Bird, A., Bock, C., Boehm, B., Campo, E., Caricasole, A., Dahl, F., Dermitzakis, E. T., Enver, T., Esteller, M., Estivill, X., Ferguson-Smith, A., Fitzgibbon, J., Flicek, P., Giehl, C., Graf, T. & 37 others, Grosveld, F., Guigo, R., Gut, I., Helin, K., Jarvius, J., Küppers, R., Lehrach, H., Lengauer, T., Lernmark, Å., Leslie, D., Loeffler, M., Macintyre, E., Mai, A., Martens, J. H. A., Minucci, S., Ouwehand, W. H., Pelicci, P. G., Pendeville, H., Porse, Bo Torben, Rakyan, V., Reik, W., Schrappe, M., Schübeler, D., Seifert, M., Siebert, R., Simmons, D., Soranzo, N., Spicuglia, S., Stratton, M., Stunnenberg, H. G., Tanay, A., Torrents, D., Valencia, A., Vellenga, E., Vingron, M., Walter, J. & Willcocks, S., 2012, In: Nature Biotechnology. 30, 3, p. 224-6 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  14. Published

    Basal stamcellebiologi og cancer

    Porse, Bo Torben, Petersen, Ole William & Helin, K., 20 Sep 2010, In: Ugeskrift for læger. 172, 38, p. 2600-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Basement membrane stiffness determines metastases formation

    Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, Maniati, E., Pearce, O. M. T., Koch, M., Oddershede, L. B., Van Agtmael, T., Madsen, C. D., Mayorca Guiliani, Alejandro Enrique, Bloch, W., Netz, R. R., Clausen-schaumann, H. & Erler, Janine, 2021, In: Nature Materials. 20, p. 892–903

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

    Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Bone Marrow-derived Macrophages (BMMs): Isolation and applications.

    Weischenfeldt, Joachim Lütken & Porse, Bo Torben, 2008, In: Cold Spring Harbor Protocols.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2009, In: BioFactors. 35, 3, p. 227-31 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    C/EBPalpha: a tumour suppressor in multiple tissues?

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2006, In: BBA General Subjects. 1766, 1, p. 88-103 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

    Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Rapin, N. P. J., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, Bo Torben, Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

    Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance

    Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cellular origin of prognostic chromosomal aberrations in AML patients

    Mora-Jensen, H., Jendholm, L. J., Rapin, N. P. J., Andersen, M. K., Roug, A. S., Bagger, F. O., Bullinger, L., Winther, Ole, Borregaard, N., Porse, Bo Torben & Theilgaard-Mønch, Kim, 11 Feb 2015, In: Leukemia. 29, p. 1785-1789 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4985646