Bo Torben Porse
Professor, Clinical Professor
Porse Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
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Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis
Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BLUEPRINT to decode the epigenetic signature written in blood
Adams, D., Altucci, L., Antonarakis, S. E., Ballesteros, J., Beck, S., Bird, A., Bock, C., Boehm, B., Campo, E., Caricasole, A., Dahl, F., Dermitzakis, E. T., Enver, T., Esteller, M., Estivill, X., Ferguson-Smith, A., Fitzgibbon, J., Flicek, P., Giehl, C., Graf, T. & 37 others, , 2012, In: Nature Biotechnology. 30, 3, p. 224-6 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA
Andersen, T., Porse, Bo Torben & Kirpekar, F., 1 Jun 2004, In: RNA. 10, 6, p. 907-913 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Jendholm, L. J., Winther, O. & Porse, Bo Torben, 2012, In: Blood. 119, 26, p. 6394-6395 2 p.Research output: Contribution to journal › Comment/debate › Research
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BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome
Bao, J., Tang, C., Yuan, S., Porse, Bo Torben & Yan, W., 2015, In: Development (Cambridge, England). 142, p. 352-362 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts
Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, Bo Torben & Yan, W., 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.Research output: Contribution to journal › Journal article › Research › peer-review
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Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome
Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.
Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mønch, Kim, Minucci, S., Porse, Bo Torben, Marine, J., Hansen, K. H. & Helin, K., 2007, In: Genes & Development. 21, 5, p. 525-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Progression of the pluripotent epiblast depends upon the NMD factor UPF2
Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice
Christoffersen, C., Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlback, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 4, p. 1839-1847 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice
Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.Research output: Contribution to journal › Journal article › Research
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Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay
Colak, D., Ji, S., Porse, Bo Torben & Jaffrey, S. R., 2013, In: Cell. 153, 6, p. 1252-65 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myelodysplastic syndrome patient-derived xenografts: from no options to many
Côme, Christophe Roger Michel, Balhuizen, Alexander, Bonnet, D. & Porse, Bo Torben, 2020, In: Haematologica. 105, 4, p. 864-869Research output: Contribution to journal › Journal article › Research › peer-review
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The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia
D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes
D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4
Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy
Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042Research output: Contribution to journal › Journal article › Research › peer-review
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Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics
Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.Research output: Contribution to journal › Journal article › Research › peer-review
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The splicing factor RBM25 controls MYC activity in acute myeloid leukemia
Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.Research output: Contribution to journal › Journal article › Research › peer-review
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The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression
Ge, Y. & Porse, Bo Torben, 18 Dec 2013, In: BioEssays.Research output: Contribution to journal › Review › Research › peer-review
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Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells
Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.Research output: Contribution to journal › Journal article › Research › peer-review
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A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines
Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.Research output: Contribution to journal › Journal article › Research › peer-review
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Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis
Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, , 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4985646
Most downloads
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3488
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spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2749
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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2492
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published