Birgitte Rahbek Kornum

Birgitte Rahbek Kornum

Guest Researcher, Associate Professor - Promotion Programme

ORCID: 0000-0002-2515-9451

Publication year:
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1 - 50 out of 101Page size: 50
  1. 2002

  2. Attenuation and scatter correction in myocardial SPET: improved diagnostic accuracy in patients with suspected coronary artery disease.

    Kjaer, A., Cortsen, A., Kornum, Birgitte Rahbek, Hasseldam, Henrik & Hesse, B., 2002, In: European Journal of Nuclear Medicine and Molecular Imaging. 29, 11, p. 1438-42 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2003
  4. Published

    The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain

    Aznar, S., Qian, Z., Shah, R., Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 3 Jan 2003, In: Brain Research. 959, 1, p. 58-67 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2006
  6. Published

    Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes

    Kornum, Birgitte Rahbek, Licht, C. L., Weikop, P., Knudsen, G. M. & Kleijn, S. A., 9 Jan 2006, In: Neuroscience Letters. 392, 1-2, p. 129-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus

    Kornum, Birgitte Rahbek, Weikop, Pia, Moller, A., Ronn, L. C. B., Knudsen, Gitte Moos & Aznar, S., 16 Feb 2006, In: Brain Research. 1073-1074, p. 262-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2007
  9. Published

    The effect of the inter-phase delay interval in the spontaneous object recognition test for pigs

    Kornum, Birgitte Rahbek, Thygesen, K. S., Nielsen, Thomas Rune, Knudsen, Gitte Moos & Lind, N. M., 6 Aug 2007, In: Behavioural Brain Research. 181, 2, p. 210-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2008
  11. Published

    A novel spatial Delayed Non-Match to Sample (DNMS) task in the Göttingen minipig

    Nielsen, T. R., Kornum, Birgitte Rahbek, Moustgaard, A. C., Gade, A., Lind, N. M. & Knudsen, Gitte Moos, 2008, In: Behavioural Brain Research. p. 93-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Evaluation of the novel 5-HT4 receptor PET ligand (11C)SB207145 in the Göttingen minnipig

    Kornum, Birgitte Rahbek, Lind, N. M., Gillings, N. M., Marner, L., Andersen, F. & Knudsen, G. M., 2008, In: Comprehensive Medline. 1, p. 186-96 10 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  13. 2009
  14. Published

    A pig model for studies of serotonergic mechanisms in memory disorders

    Kornum, Birgitte Rahbek, 2009, København: Museum Tusculanum. 69 p.

    Research output: Book/Report › Ph.D. thesis › Research

  15. Published

    Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

    Syvanen, S., Lindhe, O., Palner, M., Kornum, Birgitte Rahbek, Rahman, O., Langstrom, B., Knudsen, Gitte Moos & Hammarlund-Udenaes, M., 2009, In: Drug Metabolism and Disposition. 37, 3, p. 635-643 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Evaluation of the novel 5-HT4 receptor PET ligand [11C]SB207145 in the Göttingen minipig

    Kornum, Birgitte Rahbek, Lind, N. M., Gillings, N., Marner, Lisbeth, Andersen, F. & Knudsen, Gitte Moos, 1 Jan 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 1, p. 186-96 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2010
  18. Published

    Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain

    Kornum, Birgitte Rahbek, Stott, S. R. W., Mattsson, B., Wisman, L., Ettrup, A., Hermening, S., Knudsen, Gitte Moos & Kirik, D., 1 Mar 2010, In: Experimental Neurology. 222, 1, p. 70-85 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET

    Ettrup, A., Palner, M., Gillings, N., Santini, M. A., Hansen, M., Kornum, Birgitte Rahbek, Rasmussen, L. K., Någren, K., Madsen, J., Begtrup, M. & Knudsen, Gitte Moos, 1 Nov 2010, In: Journal of Nuclear Medicine. 51, 11, p. 1763-1770

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2011
  21. Published

    An approach for serotonin depletion in pigs: effects on serotonin receptor binding

    Ettrup, A., Kornum, Birgitte Rahbek, Weikop, P. & Knudsen, Gitte Moos, 2011, In: Synapse. 65, 2, p. 136-45 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

    Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 2011, In: Neuroscience & Biobehavioral Reviews. 35, 3, p. 437-51 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Common variants in P2RY11 are associated with narcolepsy

    Kornum, B. R., Kawashima, M., Faraco, J., Lin, L., Rico, T. J., Hesselson, S., Axtell, R. C., Kuipers, H., Weiner, K., Hamacher, A., Kassack, M. U., Han, F., Knudsen, S., Li, J., Dong, X., Winkelmann, J., Plazzi, G., Nevsimalova, S., Hong, S-C., Honda, Y. & 30 others, Honda, M., Högl, B., Ton, T. G. N., Montplaisir, J., Bourgin, P., Kemlink, D., Huang, Y., Warby, S., Einen, M., Eshragh, J. L., Miyagawa, T., Desautels, A., Ruppert, E., Hesla, P. E., Poli, F., Pizza, F., Frauscher, B., Jeong, J., Lee, S., Strohl, K. P., Longstreth, W. T., Kvale, M., Dobrovolna, M., Ohayon, M. M., Nepom, G. T., Wichmann, H., Rouleau, G. A., Gieger, C., Levinson, D. F. & Jennum, Poul, Jan 2011, In: Nature Genetics. 43, 1, p. 66-71 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain

    Kornum, Birgitte Rahbek, Faraco, J. & Mignot, E., Dec 2011, In: Current Opinion in Neurobiology. 21, 6, p. 897-903 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. 2012
  26. Published

    Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency

    Knudsen, S., Biering-Sørensen, B., Kornum, Birgitte Rahbek, Petersen, E., Ibsen, J. D., Gammeltoft, S., Mignot, E. & Jennum, Poul, 2012, In: Neurology. 79, 1, p. 102-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy

    Andlauer, O., Moore, H., Hong, S., Dauvilliers, Y., Kanbayashi, T., Nishino, S., Han, F., Silber, M. H., Rico, T., Einen, M., Kornum, Birgitte Rahbek, Jennum, Poul, Knudsen, S., Nevsimalova, S., Poli, F., Plazzi, G. & Mignot, E., 2012, In: Sleep. 35, 9, p. 1247-55F

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status

    Weiner Lachmi, K., Lin, L., Kornum, Birgitte Rahbek, Rico, T., Lo, B., Aran, A. & Mignot, E., Apr 2012, In: Human Immunology. 73, 4, p. 405-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy

    Winkelmann, J., Lin, L., Schormair, B., Kornum, Birgitte Rahbek, Faraco, J., Plazzi, G., Melberg, A., Cornelio, F., Urban, A. E., Pizza, F., Poli, F., Grubert, F., Wieland, T., Graf, E., Hallmayer, J., Strom, T. M. & Mignot, E., 15 May 2012, In: Human Molecular Genetics. 21, 10, p. 2205-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2013

  31. Association mellem narkolepsi og H1N1-influenza

    Kornum, Birgitte Rahbek, Knudsen, S., Gammeltoft, S. & Jennum, Poul, 2013, In: Ugeskrift for Laeger. 175, 12, p. 815

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Hjernens regulering af søvn

    Gammeltoft, S., Nordvang, A. H. & Kornum, Birgitte Rahbek, 2013, Søvn. Jennum, P. (ed.). 1 ed. København: Munksgaard , p. 39-50 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  33. Published

    ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

    Faraco, J., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., Einen, M., Rico, T. J., Lichtner, P., Dauvilliers, Y., Arnulf, I., Lecendreux, M., Javidi, S., Geisler, P., Mayer, G., Pizza, F., Poli, F., Plazzi, G., Overeem, S., Lammers, G. J., Kemlink, D. & 28 others, Sonka, K., Nevsimalova, S., Rouleau, G., Desautels, A., Montplaisir, J., Frauscher, B., Ehrmann, L., Högl, B., Jennum, Poul, Bourgin, P., Peraita-Adrados, R., Iranzo, A., Bassetti, C., Chen, W., Concannon, P., Thompson, S. D., Damotte, V., Fontaine, B., Breban, M., Gieger, C., Klopp, N., Deloukas, P., Wijmenga, C., Hallmayer, J., Onengut-Gumuscu, S., Rich, S. S., Winkelmann, J. & Mignot, E., 2013, In: P L o S Genetics (Online). 9, 2, 7 p., e1003270.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    5-HT radioligands for human brain imaging with PET and SPECT

    Paterson, L. M., Kornum, Birgitte Rahbek, Nutt, D. J., Pike, V. W. & Knudsen, Gitte Moos, Jan 2013, In: Medicinal Research Reviews. 33, 1, p. 54-111 58 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy

    De la Herrán-Arita, A. K., Kornum, Birgitte Rahbek, Mahlios, J., Jiang, W., Lin, L., Hou, T., Macaubas, C., Einen, M., Plazzi, G., Crowe, C., Newell, E. W., Davis, M. M., Mellins, E. D. & Mignot, E., 18 Dec 2013, In: Science Translational Medicine. 5, 216, p. 216ra176

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2014
  37. Published

    Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination

    Partinen, M., Kornum, Birgitte Rahbek, Plazzi, G., Jennum, Poul, Julkunen, I. & Vaarala, O., 2014, In: Lancet Neurology. 13, 6, p. 600-13

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Retraction of the research article: "CD4⁺ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy"

    De la Herrán-Arita, A. K., Kornum, Birgitte Rahbek, Mahlios, J., Jiang, W., Lin, L., Hou, T., Macaubas, C., Einen, M., Plazzi, G., Crowe, C., Newell, E. W., Davis, M. M., Mellins, E. D. & Mignot, E., 30 Jul 2014, In: Science Translational Medicine. 6, 247, 247rt1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    miRNA profiles in plasma from patients with sleep disorders reveal dysregulation of miRNAs in narcolepsy and other central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Kornum, Birgitte Rahbek, Modvig, S., Jennum, Poul & Gammeltoft, S., Sep 2014, In: Sleep. 37, 9, p. 1525-1533 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Does autoreactivity have a role in narcolepsy?

    Partinen, M., Kornum, Birgitte Rahbek, Plazzi, G., Jennum, Poul, Julkunen, I. & Vaarala, O., Nov 2014, In: Lancet Neurology. 13, 11, p. 1072-1073 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    miRNA profiles in cerebrospinal fluid from patients with central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Modvig, S., Kornum, Birgitte Rahbek, Gammeltoft, S. & Jennum, Poul, 15 Dec 2014, In: Journal of the Neurological Sciences. 347, 1-2, p. 199-204 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2015
  43. Published

    EIF3G is associated with narcolepsy across ethnicities

    Holm, A., Lin, L., Faraco, J., Mostafavi, S., Battle, A., Zhu, X., Levinson, D. F., Han, F., Gammeltoft, S., Jennum, Poul, Mignot, E. & Kornum, Birgitte Rahbek, 2015, In: European Journal of Human Genetics. 23, 11, p. 1573-80 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

    Justinussen, Jessica, Holm, A. & Kornum, Birgitte Rahbek, 2015, In: Neuroscience. 310, p. 354-361 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Sleep Disorders

    Kornum, Birgitte Rahbek & Mignot, E., 1 Jan 2015, Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders. Zigmond, M. J., Rowland, L. P. & Coyle, J. T. (eds.). London: Elsevier Science Inc., p. 585-611 27 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  46. Published

    HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy

    Ollila, H. M., Ravel, J-M., Han, F., Faraco, J., Lin, L., Zheng, X., Plazzi, G., Dauvilliers, Y., Pizza, F., Hong, S-C., Jennum, P., Knudsen, S., Kornum, B. R., Dong, X. S., Yan, H., Hong, H., Coquillard, C., Mahlios, J., Jolanki, O., Einen, M. & 15 others, Arnulf, I., Lavault, S., Högl, B., Frauscher, B., Crowe, C., Partinen, M., Huang, Y. S., Bourgin, P., Vaarala, O., Désautels, A., Montplaisir, J., Mack, S. J., Mindrinos, M., Fernandez-Vina, M. & Mignot, E., 8 Jan 2015, In: American Journal of Human Genetics. 96, 1, p. 136-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Serum cytokine levels in Kleine-Levin syndrome

    Kornum, Birgitte Rahbek, Rico, T., Lin, L., Huang, Y., Arnulf, I., Jennum, Poul & Mignot, E., Aug 2015, In: Sleep Medicine. 16, 8, p. 961-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Type 1 narcolepsy: a CD8+ T cell-mediated disease?

    Degn, M. & Kornum, Birgitte Rahbek, Sep 2015, In: Annals of the New York Academy of Sciences. 1351, p. 80-88 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Cerebrospinal fluid cytokine levels in type 1 narcolepsy patients very close to onset

    Kornum, Birgitte Rahbek, Pizza, F., Knudsen, S., Plazzi, G., Jennum, Poul & Mignot, E., Oct 2015, In: Brain, Behavior, and Immunity. 49, p. 54-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2016
  51. Published

    Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

    Boddum, K., Hansen, M. H., Jennum, Poul & Kornum, Birgitte Rahbek, 2016, In: PloS one. 11, 3, 13 p., e0151288.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Precipitants of Narcolepsy: Vaccines and Infections

    Kornum, Birgitte Rahbek, 2016, Narcolepsy: A Clinical Guide. 2 ed. Springer, p. 25-33 9 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  53. Published

    The European Narcolepsy Network (EU-NN) database

    Khatami, R., Luca, G., Baumann, C. R., Bassetti, C. L., Bruni, O., Canellas, F., Dauvilliers, Y., Del Rio-Villegas, R., Feketeova, E., Ferri, R., Geisler, P., Högl, B., Jennum, P., Kornum, B. R., Lecendreux, M., Martins-da-Silva, A., Mathis, J., Mayer, G., Paiva, T., Partinen, M. & 11 others, Peraita Adrados, R., Plazzi, G., Santamaria, J., Sonka, K., Riha, R., Tafti, M., Wierzbicka, A., Young, P., Lammers, G. J., Overeem, S. & European Narcolepsy Network, E. N. N., Jun 2016, In: Journal of Sleep Research. 25, 3, p. 356-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis

    Jennum, Poul, Kornum, Birgitte Rahbek, Issa, N. M., Gammeltoft, S., Tommerup, Niels, Morling, Niels, Tümer, Asuman Zeynep & Knudsen, S., Aug 2016, In: Neurology: Neuroimmunology & Neuroinflammation. 3, 4, 2 p., e249.

    Research output: Contribution to journal › Letter › Research › peer-review

  55. Published

    A critical look at the function of the P2Y11 receptor

    Dreisig, K. & Kornum, Birgitte Rahbek, Sep 2016, In: Purinergic Signalling. 12, 3, p. 427-37 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Validation of antibodies for neuroanatomical localization of the P2Y receptor in macaque brain

    Dreisig, K., Degn, M., Sund, L., Hadaczek, P., Samaranch, L., San Sebastian, W., Bankiewicz, K. & Kornum, Birgitte Rahbek, Dec 2016, In: Journal of Chemical Neuroanatomy. 78, p. 25-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Neurobasal media facilitates increased specificity of siRNA-mediated knockdown in primary cerebellar cultures

    Gustafsson, J. R., Katsioudi, G., Issazadeh-Navikas, Shohreh & Kornum, Birgitte Rahbek, 1 Dec 2016, In: Journal of Neuroscience Methods. 274, p. 116-124 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. 2017
  59. Published

    Absence of autoreactive CD4(+) T-cells targeting HLA-DQA1*01:02/DQB1*06:02 restricted hypocretin/orexin epitopes in narcolepsy type 1 when detected by EliSpot

    Kornum, Birgitte Rahbek, Burgdorf, Kristoffer Sølvsten, Holm, A., Ullum, H., Jennum, Poul & Knudsen, S., 2017, In: Journal of Neuroimmunology. 309, p. 7-11 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Genetics of Human Sleep and Sleep Disorders

    Kornum, Birgitte Rahbek, 2017, Handbook of Neurobehavioural Genetics and Phenotyping. Tucci, V. (ed.). 1 ed. New Jersey: Wiley-Blackwell, p. 295-320 26 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  61. Published

    Narcolepsy

    Kornum, Birgitte Rahbek, Knudsen, S., Ollila, H. M., Pizza, F., Jennum, Poul, Dauvilliers, Y. & Overeem, S., 2017, In: Nature Reviews. Disease Primers. 3, 19 p., 16100.

    Research output: Contribution to journal › Review › Research › peer-review

  62. Published

    The evolutionary conserved microrna MIR-137 regulates gene expression and diurnal rhythm of the wake-promoting hypocretin neuropeptides

    Holm, A., Moseholm, Kristine Frøsig, Justinussen, Jessica, Silahtaroglu, Asli, Adamantidis, A. & Kornum, Birgitte Rahbek, 2017, In: Sleep Medicine. 40, Supplement 1, p. E132-E133 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  63. Published

    Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy

    Jennum, Poul, Østergaard Pedersen, L., Czarna Bahl, J. M., Modvig, S., Fog, K., Holm, A., Kornum, Birgitte Rahbek & Gammeltoft, S., 1 Jan 2017, In: Sleep. 40, 1, 9 p., zsw006.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Normal Morning Melanin-Concentrating Hormone Levels and No Association with Rapid Eye Movement or Non-Rapid Eye Movement Sleep Parameters in Narcolepsy Type 1 and Type 2

    Schrölkamp, Maren, Jennum, Poul, Gammeltoft, S., Holm, A., Kornum, Birgitte Rahbek & Knudsen, S., Feb 2017, In: Journal of Clinical Sleep Medicine. 13, 2, p. 235-243 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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