Anne-Vibeke Lænkholm
Clinical Associate Professor
- 1992
- Published
The histology at various stages of acute rejection in concordant xenogeneic heart transplantation: A sequential study in rodents
NIELSEN, B., STEINBRÜCHEL, D. A., Lænkholm, Anne-Vibeke & KEMP, E., Jan 1992, In: APMIS. 100, 1-6, p. 249-255 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents
Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, In: APMIS Supplementum. 100, 3, p. 249-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents
Nielsen, B., Steinbrüchel, D. A., Lænkholm, Anne-Vibeke & Kemp, E., Mar 1992, The histology at various stages of acute rejection in concordant xenogeneic heart transplantation. A sequential study in rodents. 3 ed. Vol. 100. p. 249-55 7 p. (APMIS Supplementum).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 1998
- Published
Influence of storage temperature and high-temperature antigen retrieval buffers on results of immunohistochemical staining in sections stored for long periods
Grabau, D. A., Nielsen, O., Hansen, S., Nielsen, M. M., Lænkholm, Anne-Vibeke, Knoop, A. & Pfeiffer, P., 1998, In: Applied Immunohistochemistry. 6, 4, p. 209-213 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer
Knoop, A., Andreasen, P. A., Andersen, J. A., Hansen, S., Lænkholm, Anne-Vibeke, Simonsen, A. C., Andersen, J., Overgaard, J. & Rose, C., Mar 1998, In: British Journal of Cancer. 77, 6, p. 932-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients
Hansen, S., Overgaard, J., Rose, C., Knoop, A., Lænkholm, Anne-Vibeke, Andersen, J., Sørensen, F. B. & Andreasen, P. A., 13 Jan 2003, In: British Journal of Cancer. 88, 1, p. 102-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Identification of genes with altered expression in medullary breast cancer vs. ductal breast cancer and normal breast epithelia
Gjerstorff, M. F., Benoit, V. M., Lænkholm, Anne-Vibeke, Nielsen, O., Johansen, L. E. & Ditzel, H. J., Jun 2006, In: International Journal of Oncology. 28, 6, p. 1327-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Intratumor genetic heterogeneity of breast carcinomas as determined by fine needle aspiration and TaqMan low density array
Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N., Vach, W., Knoop, A., Bak, M. & Ditzel, H. J., 2007, In: Analytical Cellular Pathology. 29, 5, p. 361-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carcinoma in situ mammae
Lænkholm, Anne-Vibeke, Hoffmann, J. & Rank, F. E., 10 Sep 2007, In: Ugeskrift for Laeger. 169, 37, p. 3087-90 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78
Jakobsen, C. G., Rasmussen, N., Lænkholm, Anne-Vibeke & Ditzel, H. J., 1 Oct 2007, In: Cancer Research. 67, 19, p. 9507-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Breast cancer in situ. From pre-malignant lesion of uncertain significance to well-defined non-invasive malignant lesion. The Danish Breast Cancer Cooperative Group Register 1977-2007 revisited
Lænkholm, Anne-Vibeke, Jensen, M., Kroman, Niels Thorndahl & Rank, F., 2008, In: Acta Oncologica. 47, 4, p. 765-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classical pathological variables recorded in the Danish Breast Cancer Cooperative Group's register 1978-2006
Kiaer, H. W., Lænkholm, Anne-Vibeke, Nielsen, B. B. & Bjerre, K. D., 2008, In: Acta Oncologica. 47, 4, p. 778-83 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of genes for normalization of real-time RT-PCR data in breast carcinomas
Lyng, M. B., Lænkholm, Anne-Vibeke, Pallisgaard, N. & Ditzel, H. J., 22 Jan 2008, In: BMC Cancer. 8, p. 20Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry
Leth-Larsen, R., Lund, Rikke, Hansen, H. V., Lænkholm, Anne-Vibeke, Tarin, D., Jensen, O. N. & Ditzel, H. J., Jun 2009, In: Molecular and Cellular Proteomics. 8, 6, p. 1436-49 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Finnålsaspirationscytologi ved mammografiscreening
Engvad, B., Lænkholm, Anne-Vibeke, Schwartz, W. & Bak, M., 17 Aug 2009, In: Ugeskrift for Laeger. 171, 34, p. 2379-82 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer
Nielsen, K. V., Ejlertsen, Bent Laursen, Müller, S., Møller, S., Rasmussen, B. B., Balslev, E., Lænkholm, Anne-Vibeke, Christiansen, P. & Mouridsen, H. T., 2011, In: Breast Cancer Research and Treatment. 127, 2, p. 345-355Research output: Contribution to journal › Journal article › Research › peer-review
Effects of the change in cutoff values for human epidermal growth factor receptor 2 status by immunohistochemistry and fluorescence in situ hybridization: a study comparing conventional brightfield microscopy, image analysis-assisted microscopy, and interobserver variation
Atkinson, R., Mollerup, J., Lænkholm, Anne-Vibeke, Verardo, M., Hawes, D., Commins, D., Engvad, B., Correa, A., Ehlers, C. C. & Nielsen, K. V., 2011, In: Archives of Pathology & Laboratory Medicine. 135, 8, p. 1010-1016 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer
Dupont Jensen, J., Lænkholm, Anne-Vibeke, Knoop, A., Ewertz, M., Bandaru, R., Liu, W., Hackl, W., Barrett, J. C. & Gardner, H., 15 Feb 2011, In: Clinical Cancer Research. 17, 4, p. 667-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mortality rates among early-stage hormone receptor-positive breast cancer patients: a population-based cohort study in Denmark
Danish Breast Cancer Cooperative Group, D. B. C. C. G., 21 Sep 2011, In: Journal of the National Cancer Institute. 103, 18, p. 1363-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Cytokeratin on frozen sections of sentinel node may spare breast cancer patients secondary axillary surgery
Stovgaard, E. S., Tvedskov, Tove Filtenborg, Lænkholm, Anne-Vibeke & Balslev, E., 2012, In: Pathology Research International. 2012, p. 802184Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ER, HER2, and TOP2A expression in primary tumor, synchronous axillary nodes, and asynchronous metastases in breast cancer
Jensen, J. D., Knoop, A., Ewertz, M. & Lænkholm, Anne-Vibeke, Apr 2012, In: Breast Cancer Research and Treatment. 132, 2, p. 511-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implementation of TMA and digitalization in routine diagnostics of breast pathology
Rossing, H. H., Talman, M. M., Lænkholm, Anne-Vibeke & Wielenga, V. T., Apr 2012, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica (Online). 120, 4, p. 341-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen, Lykkesfeldt, A. E. & Rasmussen, B. B., Jul 2012, In: Acta Oncologica. 51, 6, p. 781-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics of primary tumors with varying metastatic capabilities using stable isotope-labeled proteins of multiple histogenic origins
Lund, Rikke, Terp, M. G., Lænkholm, Anne-Vibeke, Jensen, O. N., Leth-Larsen, R. & Ditzel, H. J., Jul 2012, In: Proteomics. 12, 13, p. 2139-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry
Lænkholm, Anne-Vibeke, Knoop, A., Ejlertsen, Bent Laursen, Rudbeck, T., Jensen, M., Müller, S., Lykkesfeldt, A. E., Rasmussen, B. B. & Nielsen, K. V., Aug 2012, In: Molecular Oncology. 6, 4, p. 428-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab
Jensen, J. D., Knoop, A., Lænkholm, Anne-Vibeke, Grauslund, M., Jensen, M. B., Santoni Rugiu, Eric, Andersson, M. & Ewertz, M., Aug 2012, In: Annals of oncology : official journal of the European Society for Medical Oncology. 23, 8, p. 2034-2042 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breast cancer stem cells: A moving target for cancer nanomedicine
Mollenhauer, J., Knoop, A., Bak, M., Lænkholm, Anne-Vibeke, Thomassen, M., Kruse, T. A. & Hoilund-Carlsen, P. F., Dec 2012, In: European Journal of Nanomedicine. 4, 2-4, p. 59-72 14 p.Research output: Contribution to journal › Review › Research › peer-review
- 2013
- Published
Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling
Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, Thomas van Overeem, Ejlertsen, Bent Laursen, Gerdes, Anne-Marie Axø & Thomassen, M., 2013, In: P L o S One. 8, 5, 12 p., e64268.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study
Lyng, M. B., Lænkholm, Anne-Vibeke, Tan, Q., Vach, W., Gravgaard, K. H., Knoop, A. & Ditzel, H., 2013, In: PLOS ONE. 8, 1, p. e54078Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Estrogen receptor, Progesterone receptor, HER2 status and Ki67 index and responsiveness to adjuvant tamoxifen in postmenopausal high-risk breast cancer patients enrolled in the DBCG 77C trial
Knoop, A. S., Lænkholm, Anne-Vibeke, Jensen, M., Nielsen, K. V., Andersen, J., Nielsen, D., Ejlertsen, B. & Danish Breast Cancer Cooperative Group, D. B. C. C. G., 2014, In: European journal of cancer (Oxford, England : 1990). 50, 8, p. 1412-1421 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families
Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, Anne-Marie Axø, 2014, In: B M C Medical Genomics. 7, p. 9Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
An international study to increase concordance in Ki67 scoring
Polley, M-Y. C., Leung, S. C. Y., Gao, D., Mastropasqua, M. G., Zabaglo, L. A., Bartlett, J. M. S., McShane, L. M., Enos, R. A., Badve, S. S., Bane, A. L., Borgquist, S., Fineberg, S., Lin, M-G., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Moriya, T., Ohi, Y., Osborne, C. K. & 11 others, , 2015, In: Modern Pathology. 28, 6, p. 778-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis
Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Kruse, T. A. & Thomassen, M., 2015, In: OncoTarget. 6, 8, p. 5634-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment
Larsen, S. L., Lænkholm, Anne-Vibeke, Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 2015, In: PloS one. 10, 2, e0118346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer
Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.Research output: Contribution to journal › Journal article › Research › peer-review
Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy
Elias, D., Vever, H., Lænkholm, Anne-Vibeke, Gjerstorff, M. F., Yde, C. W., Lykkesfeldt, A. E. & Ditzel, H. J., 9 Apr 2015, In: Oncogene. 34, 15, p. 1919-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells
Thrane, Susan, Pedersen, A. M., Thomsen, M. B. H., Kirkegaard, T., Rasmussen, B. B., Duun-Henriksen, A. K., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E. & Yde, C. W., 6 Aug 2015, In: Oncogene. 34, 32, p. 4199-210 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer
Lund, R. R., Leth-Larsen, R., Caterino, T. D., Terp, M. G., Nissen, J., Lænkholm, Anne-Vibeke, Jensen, O. N. & Ditzel, H. J., Nov 2015, In: Molecular and Cellular Proteomics. 14, 11, p. 2988-99 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression alterations associated with outcome in aromatase inhibitor-treated ER+ early-stage breast cancer patients
Thomsen, K. G., Lyng, M. B., Elias, D., Vever, H., Knoop, A. S., Lykkesfeldt, A. E., Lænkholm, Anne-Vibeke & Ditzel, H. J., Dec 2015, In: Breast Cancer Research and Treatment. 154, 3, p. 483-94 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, , 2016, In: npj Breast Cancer. 2, p. 16014Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Nine Somatic Variant Callers for Detection of Somatic Mutations in Exome and Targeted Deep Sequencing Data
Krøigård, A. B., Thomassen, M., Lænkholm, Anne-Vibeke, Kruse, T. A. & Larsen, M. J., 2016, In: PloS one. 11, 3, 15 p., e0151664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of prediction of local recurrence (LR) by Prosigna® (PAM50) in a Danish breast cancer cooperative group (DBCG) cohort of hormone receptor positive (HR+), postmenopausal early breast cancer (EBC) patients allocated to 5yr of endocrine therapy (ET)
Eriksen, J. O., Jensen, M., Lænkholm, Anne-Vibeke, Kibøll, T., Rasmussen, B. B., Knoop, A. S., Ferree, S., Haffner, T., Buckingham, W., Schaper, C. & Ejlertsen, B., 2016, In: Cancer Research. 76, 4 Supplement, 1 p., P2-08-10.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: a Danish cohort study
Erichsen, R., Kelsh, M. A., Oliner, K. S., Nielsen, K. B., Frøslev, T., Lænkholm, Anne-Vibeke, Vyberg, M., Acquavella, J. & Sørensen, H. T., Jul 2016, In: Annals of Epidemiology. 26, 7, p. 500-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Krøigård, A. B., Larsen, M. J., Brasch-Andersen, C., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Thomassen, M. & Kruse, T. A., 2017, In: Scientific Reports. 7, 9 p., 43813.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, , 2017, In: Nature Genetics. 49, 12, p. 1767-1778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer
Holten-Rossing, H., Talman, M. M., Jylling, A. M. B., Lænkholm, Anne-Vibeke, Kristensson, M. & Vainer, B., Dec 2017, In: Histopathology. 71, 6, p. 866-873Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)
Lænkholm, Anne-Vibeke, Grabau, D., Talman, M. M., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Rasmussen, B. B., 2018, In: Acta Oncologica. 57, 1, p. 83-89 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG
Soenderstrup, I. M. H., Lænkholm, Anne-Vibeke, Jensen, M. B., Eriksen, J. O., Gerdes, Anne-Marie Axø, Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 95-101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between circulating cell-free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA-mutated metastatic breast cancer
Kodahl, A. R., Ehmsen, S., Pallisgaard, N., Jylling, A. M. B., Jensen, J. D., Lænkholm, Anne-Vibeke, Knoop, A. S. & Ditzel, H. J., 2018, In: Molecular Oncology. 12, 6, p. 925-935 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
Most downloads
-
94
downloads
Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
82
downloads
Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
82
downloads
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published