Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor


  1. 2015
  2. Published

    Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

    Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L., Nordestgaard, Børge, Pajukanta, P., Parhofer, K. G., Raal, F. J., Ray, K. K., Santos, R. D., Stalenhoef, A. F. H., Steinhagen-Thiessen, E., Stroes, E. S., Taskinen, M., Tybjærg-Hansen, Anne, Wiklund, O. & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Genetic Variation in NPC1L1 and Risk of Gallstone Disease

    Lauridsen, B. K., Stender, S. & Tybjærg-Hansen, Anne, 1 Sep 2015, In: Journal of the American College of Cardiology. 66, 9, p. 1086 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study

    Haase, C. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Sep 2015, In: Diabetes. 64, 9, p. 3328-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease

    Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Novel genes in LDL metabolism: a comprehensive overview

    Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Do, R., Stitziel, N. O., Won, H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R., Stewart, A. F. R., Saleheen, D., Danesh, J., Epstein, S. E., Sivapalaratnam, S., Hovingh, G. K., Kastelein, J. J., Samani, N. J., Schunkert, H., Erdmann, J., Shah, S. H., Kraus, W. E., Davies, R., Nikpay, M., Johansen, C. T., Wang, J., Hegele, R. A., Hechter, E., Marz, W., Kleber, M. E., Huang, J., Johnson, A. D., Li, M., Burke, G. L., Gross, M., Liu, Y., Assimes, T. L., Heiss, G., Lange, E. M., Tybjærg-Hansen, Anne & NHLBI Exome Sequencing Project, N. E. S. P., 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.

    Research output: Contribution to journalLetterResearchpeer-review

  9. Published

    Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women

    Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Plasma levels of apolipoprotein E and risk of dementia in the general population

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease

    Varbo, A., Benn, Marianne, Smith, G. D., Timpson, N. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2015, In: Circulation Research. 116, 4, p. 665-673 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

    Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J. A., Drenos, F., Li, Y. R., Lowe, G., Gallacher, J., Stewart, M. C. W., Tzoulaki, I., Buxbaum, S. G., van der A, D. L., Forouhi, N. G., Onland-Moret, N. C., van der Schouw, Y. T., Schnabel, R. B., Hubacek, J. A., Kubinova, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S., Baldassarre, D., Sennblad, B., Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J. W., Westendorp, Rudi GJ, de Borst, G. J., de Jong, P. A., Algra, A., Spiering, W., Maitland-van der Zee, A. H., Klungel, O. H., de Boer, A., Doevendans, P. A., Eaton, C. B., Robinson, J. G., Duggan, D., Kjekshus, J., Downs, J. R., Gotto, A. M., Keech, A. C., Marchioli, R., Tognoni, G., Sever, P. S., Poulter, N. R., Waters, D. D., Pedersen, T. R., Amarenco, P., Nakamura, H., McMurray, J. J. V., Lewsey, J. D., Chasman, D. I., Ridker, P. M., Maggioni, A. P., Tavazzi, L., Ray, K. K., Seshasai, S. R. K., Manson, J. E., Price, J. F., Whincup, P. H., Morris, R. W., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Schreiner, P. J., Fornage, M., Siscovick, D. S., Cushman, M., Kumari, M., Wareham, N. J., Verschuren, W. M. M., Redline, S., Patel, S. R., Whittaker, J. C., Hamsten, A., Delaney, J. A., Dale, C., Gaunt, T. R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B. A., van der Harst, P., Brunner, E. J., Tybjærg-Hansen, Anne, Marmot, M. G., Krauss, R. M., Tsai, M., Coresh, J., Hoogeveen, R. C., Psaty, B. M., Lange, L. A., Hakonarson, H., Dudbridge, F., Humphries, S. E., Talmud, P. J., Kivimäki, M., Timpson, N. J., Langenberg, C., Asselbergs, F. W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J. G., Reiner, A. P., Keating, B. J., Hingorani, A. D. & Sattar, N., 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

    Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I., Beales, P., Benn, Marianne, Bentham, J., Bhattacharya, S., Birney, E., Blackwood, D., Bobrow, M., Bochukova, E., Bolton, P. F., Bounds, R., Boustred, C., Breen, G., Calissano, M., Carss, K., Pablo Casas, J., Chambers, J. C., Charlton, R., Chatterjee, K., Chen, L., Ciampi, A., Cirak, S., Clapham, P., Clement, G., Coates, G., Cocca, M., Collier, D. A., Cosgrove, C., Cox, T., Craddock, N., Crooks, L., Curran, S., Curtis, D., Daly, A., Day, I. N. M., Day-williams, A., Dedoussis, G., Down, T., Du, Y., Van Duijn, C. M., Dunham, I., Edkins, S., Ekong, R., Ellis, P., Evans, D. M., Farooqi, I. S., Fitzpatrick, D. R., Flicek, P., Floyd, J., Foley, A. R., Franklin, C. S., Futema, M., Gallagher, L., Gasparini, P., Gaunt, T. R., Geihs, M., Geschwind, D., Greenwood, C., Griffin, H., Grozeva, D., Guo, X., Guo, X., Gurling, H., Hart, D., Hendricks, A. E., Holmans, P., Huang, L., Hubbard, T., Humphries, S. E., Hurles, M. E., Hysi, P., Iotchkova, V., Isaacs, A., Jackson, D. K., Jamshidi, Y., Johnson, J., Joyce, C., Karczewski, K. J., Kaye, J., Keane, T., Kemp, J. P., Kennedy, K., Kent, A., Keogh, J., Khawaja, F., Kleber, M. E., Van Kogelenberg, M., Kolb-kokocinski, A., Kooner, J. S., Lachance, G., Langenberg, C., Langford, C., Lawson, D., Lee, I., Van Leeuwen, E. M., Lek, M., Li, R., Li, Y., Liang, J., Lin, H., Liu, R., Lönnqvist, J., Lopes, L. R., Lopes, M., Luan, J., Macarthur, D. G., Mangino, M., Marenne, G., März, W., Maslen, J., Matchan, A., Mathieson, I., Mcguffin, P., Mcintosh, A. M., Mckechanie, A. G., Mcquillin, A., Metrustry, S., Migone, N., Mitchison, H. M., Moayyeri, A., Morris, J., Morris, R., Muddyman, D., Muntoni, F., Nordestgaard, Børge, Northstone, K., O'donovan, M. C., O'rahilly, S., Onoufriadis, A., Oualkacha, K., Owen, M. J., Palotie, A., Panoutsopoulou, K., Parker, V., Parr, J. R., Paternoster, L., Paunio, T., Payne, F., Payne, S. J., Perry, J. R. B., Pietilainen, O., Plagnol, V., Pollitt, R. C., Povey, S., Quail, M. A., Quaye, L., Raymond, L., Rehnström, K., Ridout, C. K., Ring, S., Ritchie, G. R. S., Roberts, N., Robinson, R. L., Savage, D. B., Scambler, P., Schiffels, S., Schmidts, M., Schoenmakers, N., Scott, R. H., Scott, R. A., Semple, R. K., Serra, E., Sharp, S. I., Shaw, A., Shihab, H. A., Shin, S., Skuse, D., Small, K. S., Smee, C., Smith, G. D., Southam, L., Spasic-boskovic, O., Spector, T. D., St Clair, D., St Pourcain, B., Stalker, J., Stevens, E., Sun, J., Surdulescu, G., Suvisaari, J., Syrris, P., Tachmazidou, I., Taylor, R., Tian, J., Tobin, M. D., Toniolo, D., Traglia, M., Tybjærg-Hansen, Anne, Valdes, A. M., Vandersteen, A. M., Varbo, A., Vijayarangakannan, P., Visscher, P. M., Wain, L. V., Walters, J. T. R., Wang, G., Wang, J., Wang, Y., Ward, K., Wheeler, E., Whincup, P., Whyte, T., Williams, H. J., Williamson, K. A., Wilson, C., Wilson, S. G., Wong, K., Xu, C., Yang, J., Zaza, G., Zeggini, E., Zhang, F., Zhang, P., Zhang, W., Gambaro, G., Richards, J. B., Durbin, R., Timpson, N. J., Marchini, J. & Soranzo, N., 2015, In: Nature Communications. 6, 9 p., 8111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Subgroups at high risk for ischaemic heart disease:identification and validation in 67 000 individuals from the general population

    Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dyson, G., Haase, C. L., Benn, Marianne, Nordestgaard, Børge & Sing, C. F., 2015, In: International Journal of Epidemiology. 44, 1, p. 117-128 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The UK10K project identifies rare variants in health and disease

    Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E., Zeggini, E., Barrett, J. C., Plagnol, V., Richards, J. B., Greenwood, C. M. T., Timpson, N. J., Durbin, R., Soranzo, N., Bala, S., Clapham, P., Coates, G., Cox, T., Daly, A., Danecek, P., Du, Y., Durbin, R., Edkins, S., Ellis, P., Flicek, P., Guo, X., Guo, X., Huang, L., Jackson, D. K., Joyce, C., Keane, T., Kolb-Kokocinski, A., Langford, C., Li, Y., Liang, J., Lin, H., Liu, R., Maslen, J., McCarthy, S., Muddyman, D., Quail, M. A., Stalker, J., Sun, J., Tian, J., Wang, G., Wang, J., Wang, Y., Wong, K., Zhang, P., Barroso, I., Birney, E., Boustred, C., Chen, L., Clement, G., Cocca, M., Danecek, P., Smith, G. D., Day, I. N. M., Day-Williams, A., Down, T., Dunham, I., Durbin, R., Evans, D. M., Gaunt, T. R., Geihs, M., Greenwood, C. M. T., Hart, D., Hendricks, A. E., Howie, B., Huang, J., Hubbard, T., Hysi, P., Iotchkova, V., Jamshidi, Y., Karczewski, K. J., Kemp, J. P., Lachance, G., Lawson, D., Lek, M., Lopes, M., MacArthur, D. G., Marchini, J., Mangino, M., Mathieson, I., McCarthy, S., Memari, Y., Metrustry, S., Min, J. L., Moayyeri, A., Muddyman, D., Northstone, K., Panoutsopoulou, K., Paternoster, L., Perry, J. R. B., Quaye, L., Richards, J. B., Ring, S., Ritchie, G. R. S., Schiffels, S., Shihab, H. A., Shin, S., Small, K. S., Artigas, M. S., Soranzo, N., Southam, L., Spector, T. D., St Pourcain, B., Surdulescu, G., Tachmazidou, I., Timpson, N. J., Tobin, M. D., Valdes, A. M., Visscher, P. M., Wain, L. V., Walter, K., Ward, K., Wilson, S. G., Wong, K., Yang, J., Zeggini, E., Zhang, F., Zheng, H., Anney, R., Ayub, M., Barrett, J. C., Blackwood, D., Bolton, P. F., Breen, G., Collier, D. A., Craddock, N., Crooks, L., Curran, S., Curtis, D., Durbin, R., Gallagher, L., Geschwind, D., Gurling, H., Holmans, P., Lee, I., Lonnqvist, J., McCarthy, S., McGuffin, P., McIntosh, A. M., McKechanie, A. G., McQuillin, A., Morris, J., Muddyman, D., O'Donovan, M. C., Owen, M. J., Palotie, A., Parr, J. R., Paunio, T., Pietilainen, O., Rehnstrom, K., Sharp, S. I., Skuse, D., St Clair, D., Suvisaari, J., Walters, J. T. R., Williams, H. J., Barroso, I., Bochukova, E., Bounds, R., Dominiczak, A., Durbin, R., Farooqi, I. S., Hendricks, A. E., Keogh, J., Marenne, G. L., McCarthy, S., Morris, A., Muddyman, D., O'Rahilly, S., Porteous, D. J., Smith, B. H., Tachmazidou, I., Wheeler, E., Zeggini, E., Al Turki, S., Anderson, C. A., Antony, D., Barroso, I., Beales, P., Bentham, J., Bhattacharya, S., Calissano, M., Carss, K., Chatterjee, K., Cirak, S., Cosgrove, C., Durbin, R., Fitzpatrick, D. R., Floyd, J., Foley, A. R., Franklin, C. S., Futema, M., Grozeva, D., Humphries, S. E., Hurles, M. E., McCarthy, S., Mitchison, H. M., Muddyman, D., Muntoni, F., O'Rahilly, S., Onoufriadis, A., Parker, V., Payne, F., Plagnol, V., Raymond, F. L., Roberts, N., Savage, D. B., Scambler, P., Schmidts, M., Schoenmakers, N., Semple, R. K., Serra, E., Spasic-Boskovic, O., Stevens, E., van Kogelenberg, M., Vijayarangakannan, P., Walter, K., Williamson, K. A., Wilson, C., Whyte, T., Ciampi, A., Greenwood, C. M. T., Hendricks, A. E., Li, R., Metrustry, S., Oualkacha, K., Tachmazidou, I., Xu, C., Zeggini, E., Bobrow, M., Bolton, P. F., Durbin, R., Fitzpatrick, D. R., Griffin, H., Hurles, M. E., Kaye, J., Kennedy, K., Kent, A., Muddyman, D., Muntoni, F., Raymond, F. L., Semple, R. K., Smee, C., Spector, T. D., Timpson, N. J., Charlton, R., Ekong, R., Futema, M., Humphries, S. E., Khawaja, F., Lopes, L. R., Migone, N., Payne, S. J., Plagnol, V., Pollitt, R. C., Povey, S., Ridout, C. K., Robinson, R. L., Scott, R. H., Shaw, A., Syrris, P., Taylor, R., Vandersteen, A. M., Barrett, J. C., Barroso, I., Smith, G. D., Durbin, R., Farooqi, I. S., Fitzpatrick, D. R., Hurles, M. E., Kaye, J., Kennedy, K., Langford, C., McCarthy, S., Muddyman, D., Owen, M. J., Palotie, A., Richards, J. B., Soranzo, N., Spector, T. D., Stalker, J., Timpson, N. J., Zeggini, E., Amuzu, A., Casas, J. P., Chambers, J. C., Cocca, M., Dedoussis, G., Gambaro, G., Gasparini, P., Gaunt, T. R., Huang, J., Iotchkova, V., Isaacs, A., Johnson, J., Kleber, M. E., Kooner, J. S., Langenberg, C., Luan, J., Malerba, G., Maerz, W., Matchan, A., Min, J. L., Morris, R., Nordestgaard, Børge, Ring, S., Scott, R. A., Soranzo, N., Southam, L., Timpson, N. J., Toniolo, D., Traglia, M., Tybjærg-Hansen, Anne, van Duijn, C. M., van Leeuwen, E. M., Varbo, A., Whincup, P., Zaza, G., Zeggini, E., Zhang, W. & Benn, Marianne, 2015, In: Nature. 526, 7571, p. 82-90 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 924951