Anne Tybjærg-Hansen
Clinical Professor
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Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function
Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., Van Den Bosch, M. T., Teasdale, J. E., Jones, M., Bond, M., Harper, M. T., Falk, L., Groom, A., Hazell, G. G. J., Paternoster, L., Munafò, M. R., Nordestgaard, B. G., Tybjærg-Hansen, A., Bojesen, S. E., Relton, C., Min, J. L. & 4 others, , 2022, In: Circulation Research. 130, 3, p. 384-400 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies
Pennells, L., Kaptoge, S., Wood, A., Sweeting, M., Zhao, X., White, I., Burgess, S., Willeit, P., Bolton, T., Moons, K. G. M., van der Schouw, Y. T., Selmer, R., Khaw, K-T., Gudnason, V., Assmann, G., Amouyel, P., Salomaa, V., Kivimaki, M., Nordestgaard, B. G., Blaha, M. J. & 255 others, , 2019, In: European Heart Journal. 40, 7, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Estrogen receptor alpha polymorphism and risk of cardiovascular disease, cancer, and hip fracture: cross-sectional, cohort, and case-control studies and a meta-analysis
Kjaergaard, A., Ellervik, C., Tybjaerg-Hansen, A., Axelsson, C., Grønholdt, M., Grande, P., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne, Kjaergaard, A. D., Ellervik, Christina, Axelsson, C. K., Grønholdt, M., Grande, P. & Nordestgaard, Børge, 2007, In: Circulation. 115, 7, p. 861-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011
Bernini, F., Costet, P., Ehrenborg, E., Fisher, R., Fielding, B., Freeman, D., Groen, A., Malle, E., Mulder, M., Niemeier, A., Tybjærg-Hansen, Anne & von Eckardstein, A., 2012, In: Atherosclerosis. 221, p. 287-93Research output: Contribution to journal › Journal article › Research
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European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008
Bernini, F., Freeman, D., Groen, A., Heeren, J., Kalopissis, A., Kronenberg, F., Lindstedt, K., Parini, P., Schuster, G., Tybjærg-Hansen, Anne, Dij, K. W. V. & Eckardstein, A. V., 2009, In: Atherosclerosis. 205, 1, p. 41-47 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Do, R., Stitziel, N. O., Won, H-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R. & 31 others, , 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Kozlitina, J., Smagris, E., Stender, Stefan, Nordestgaard, Børge, Zhou, H. H., Tybjærg-Hansen, Anne, Vogt, T. F., Hobbs, H. H. & Cohen, J. C., Apr 2014, In: Nature Genetics. 46, 4, p. 352-356 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
Lawlor, D. A., Nordestgaard, Børge, Benn, Marianne, Zuccolo, L., Tybjærg-Hansen, Anne & Davey Smith, G., 14 Mar 2013, In: European Heart Journal (Online).Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme Bilirubin Levels as a Causal Risk Factor for Symptomatic Gallstone Disease
Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Annals of Internal Medicine. 173, 13, p. 1222-1228 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women
Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and improved cardiovascular risk prediction
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 19 Mar 2013, In: Journal of the American College of Cardiology. 61, 11, p. 1146-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study
Kamstrup, P. R., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2008, In: Circulation. 117, 2, p. 176-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factor V leiden homozygosity, dyspnea, and reduced pulmonary function.
Juul, K., Tybjærg-Hansen, A., Lange, P., Vestbo, J., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Archives of Internal Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L. & 13 others, , 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease Consensus Statement of the European Atherosclerosis Society
Nordestgaard, B. G., Chapman, M. J., Humphries, S. E., Ginsberg, H. N., Masana, L., Descamps, O. S., Wiklund, O., Hegele, R. A., Raal, F. J., Defesche, J. C., Wiegman, A., Santos, R. D., Watts, G. F., Parhofer, K. G., Hovingh, G. K., Kovanen, P. T., Boileau, C., Averna, M., Borén, J., Bruckert, E. & 9 others, , 2013, In: European Heart Journal. 34, 45, p. 3478-3490Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 3956-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fatalt forløb ved in vitro-fertilisation
Sørensen, Martin Kryspin, Møller-Sørensen, H., Svane, C., Jensen, C. H., Lange, Kai & Tybjærg-Hansen, Anne, 17 May 2010, In: Ugeskrift for Laeger. 172, 20, p. 1537-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W. K., Young, R., Paul, D. S., Waite, L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H-H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 36 others, , 2017, In: Nature Genetics. 49, p. 1113-1119Research output: Contribution to journal › Letter › Research › peer-review
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Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion
Dahl, M., Nordestgaard, Børge, Lange, Peter & Tybjærg-Hansen, Anne, May 2001, In: Journal of Allergy and Clinical Immunology. 107, 5, p. 818-23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies
Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J. & 35 others, , Aug 2016, In: Gastroenterology. 151, 2, 351 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional promoter variant in zinc finger protein 202 predicts severe atherosclerosis and ischemic heart disease
Frikke-Schmidt, Ruth, Nordestgaard, Børge, Grande, P., Tybjærg-Hansen, Anne & Schnohr, P., 2008, In: Journal of the American College of Cardiology. 52, 5, p. 369-377 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Zeller, T., Liquet, B., Newcombe, P., Yengo, L., Wild, P. S., Schillert, A., Ziegler, A., Nielsen, S. F., Butterworth, A. S., Ho, W. K., Castagné, R., Munzel, T., Tregouet, D., Falchi, M., Cambien, F., Nordestgaard, B., Fumeron, F. & 7 others, , 2013, In: P L o S Genetics. 9, 8, p. 1-17 17 p., e1003657.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variants Associated With Increased Plasma Levels of Triglycerides, via Effects on the Lipoprotein Lipase Pathway, Increase Risk of Acute Pancreatitis
Hansen, S. E. J., Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Clinical Gastroenterology and Hepatology. 19, 8, p. 1652-1660.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose
Seidelin, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Journal of Clinical Endrocrinology and Metabolism. 105, 6, p. 1963–1972Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation in NPC1L1 and Risk of Gallstone Disease
Lauridsen, B. K., Stender, S. & Tybjærg-Hansen, Anne, 1 Sep 2015, In: Journal of the American College of Cardiology. 66, 9, p. 1086 1 p.Research output: Contribution to journal › Letter › Research › peer-review
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Genetic Variation in ABCG1 and Risk of Myocardial Infarction and Ischemic Heart Disease
Schou, J., Frikke-Schmidt, R., Kardassis, D., Thymiakou, E., Nordestgaard, Børge, Jensen, G., Grande, P. & Tybjærg-Hansen, Anne, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, p. 506-15 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation in GSTP1, Lung Function, Risk of Lung Cancer, and Mortality
Nørskov, M. S., Dahl, Morten & Tybjærg-Hansen, Anne, Nov 2017, In: Journal of Thoracic Oncology. 12, 11, p. 1664-1672 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation in Liver X Receptor Alpha and Risk of Ischemic Vascular Disease in the General Population
Stender, Stefan, Frikke-Schmidt, Ruth, Sethi, A. A., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 8-9 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
Dewey, F. E., Gusarova, V., Dunbar, R. L., O'Dushlaine, C. T., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., Leader, J. B., Murray, M. F., Ritchie, M. D., Kirchner, H. L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N. & 37 others, , Jul 2017, In: New England Journal of Medicine. 377, 3, p. 211-221Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic associations with valvular calcification and aortic stenosis
Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., Malhotra, R., O'Brien, K. D., Kamstrup, P. R., Nordestgaard, B. G., Tybjaerg-Hansen, A., Allison, M. A., Aspelund, T., Criqui, M. H., Heckbert, S. R., Hwang, S-J. & 20 others, , 7 Feb 2013, In: New England Journal of Medicine. 368, 6, p. 503-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk
Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Current Opinion in Lipidology. 22, 2, p. 113-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium
Wassel, C. L., Lamina, C., Nambi, V., Coassin, S., Mukamal, K. J., Ganesh, S. K., Jacobs, D. R., Franceschini, N., Papanicolaou, G. J., Gibson, Q., Yanek, L. R., van der Harst, P., Ferguson, J. F., Crawford, D. C., Waite, L. L., Allison, M. A., Criqui, M. H., McDermott, M. M., Mehra, R., Cupples, L. A. & 41 others, , 2012, In: Atherosclerosis. 222, 1, p. 138-47 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 7, p. 1732-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P. & 61 others, , 2018, In: Nature Communications. 9, 1, 2252.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects
Johannsen, T. H., Frikke-Schmidt, R., Schou, J., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: Journal of the American College of Cardiology. 60, 20, p. 2041-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk of fatty liver disease and mortality in the general population: A Mendelian randomization study
Gellert-Kristensen, H., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ghouse, Jonas, Fuchs, A., Kühl, J. T., Sigvardsen, P. E., Kofoed, Klaus Fuglsang & Stender, S., 2023, In: Liver International. 43, 9, p. 1955-1965 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy
Hornstrup, L. S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jun 2013, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1441-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in SUSD2 are associated with the risk of ischemic heart disease
Bruikman, C. S., Dalila, N., van Capelleveen, J. C., Kroon, J., Peter, J., Havik, S. R., Willems, M., Huisman, L. C., de Boer, O. J., Hovingh, G. K., Tybjærg-Hansen, Anne & Dallinga-Thie, G. M., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 470-481Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease
Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Journal of Epidemiology. 38, 9, p. 985-994 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses
Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population
Frikke-Schmidt, R., Nordestgaard, Børge, Jensen, G. B. & Tybjærg-Hansen, Anne, 2004, In: Journal of Clinical Investigation. 114, 9, p. 1343-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in ABCA1 and risk of all-cause dementia, age-related macular degeneration, and ischemic heart disease
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Atherosclerosis. 331, p. E38-E39 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genetic variation in ABCA1 predicts ischemic heart disease in the general population
Frikke-Schmidt, Ruth, Nordestgaard, B., Jensen, G. B., Steffensen, R., Tybjaerg-Hansen, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Frikke-Schmidt, R. & Steffensen, R., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 1, p. 180-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in liver x receptor alpha and risk of ischemic vascular disease in the general population
Stender, S., Frikke-Schmidt, R., Anestis, A., Kardassis, D., Sethi, A. A., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 12, p. 2990-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease
Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically Reduced Soluble Epoxide Hydrolase Activity and Risk of Stroke and Other Cardiovascular Disease
Lee, J., Dahl, Morten, Grande, P., Tybjærg-Hansen, Anne & Nordestgaard, B. G., Jan 2010, In: Stroke. 41, 1, p. 27-33Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated C-reactive protein and ischemic vascular disease
Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2008, In: New England Journal of Medicine. 359, 18, p. 1897-1908 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
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