Anne Tybjærg-Hansen
Clinical Professor
- 2013
- Published
Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses
Stender, S., Frikke-Schmidt, R., Benn, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Journal of Hepatology. 58, 1, p. 126-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remnant cholesterol as a causal risk factor for ischemic heart disease
Varbo, A., Benn, M., Tybjærg-Hansen, Anne, Jørgensen, A. B., Frikke-Schmidt, R. & Nordestgaard, Børge, 2013, In: Journal of the American College of Cardiology. 61, 4, p. 427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretory Phospholipase A2-IIA and Cardiovascular Disease
Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L. W., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A. & 93 others, , 2013, In: Journal of the American College of Cardiology. 62 , 21, p. 1966–1976 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
YKL-40 levels and atrial fibrillation in the general population
Marott, S. C. W., Benn, M., Johansen, J. S., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: International Journal of Cardiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Splice site mutations in mismatch repair genes and risk of cancer in the general population
Thomsen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Bojesen, S. E., 18 Jan 2013, In: Familial Cancer.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic associations with valvular calcification and aortic stenosis
Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., Malhotra, R., O'Brien, K. D., Kamstrup, P. R., Nordestgaard, B. G., Tybjaerg-Hansen, A., Allison, M. A., Aspelund, T., Criqui, M. H., Heckbert, S. R., Hwang, S-J. & 20 others, , 7 Feb 2013, In: New England Journal of Medicine. 368, 6, p. 503-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
Lawlor, D. A., Nordestgaard, Børge, Benn, Marianne, Zuccolo, L., Tybjærg-Hansen, Anne & Davey Smith, G., 14 Mar 2013, In: European Heart Journal (Online).Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme lipoprotein(a) levels and improved cardiovascular risk prediction
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 19 Mar 2013, In: Journal of the American College of Cardiology. 61, 11, p. 1146-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short telomere length, cancer survival, and cancer risk in 47102 individuals
Weischer, M., Nordestgaard, Børge, Cawthon, R. M., Freiberg, J. J., Tybjærg-Hansen, Anne & Bojesen, S. E., 3 Apr 2013, In: National Cancer Institute. Journal (Print). 105, 7, p. 459-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy
Hornstrup, L. S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jun 2013, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1441-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis
Singh, G. M., Danaei, G., Farzadfar, F., Stevens, G. A., Woodward, M., Wormser, D., Kaptoge, S., Whitlock, G., Qiao, Q., Lewington, S., Di Angelantonio, E., Vander Hoorn, S., Lawes, C. M. M., Ali, M. K., Mozaffarian, D., Ezzati, M., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Benn, Marianne & Nordestgaard, Børge, Jul 2013, In: P L o S One. 8, 7, p. 1-10 10 p., e65174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Total mortality by elevated transferrin saturation in patients with diabetes
Ellervik, Christina, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H., Nordestgaard, Børge & Mandrup-Poulsen, Thomas, Sep 2013, In: Diabetes Care. 36, 9, p. 2646-54 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutathione S-transferases T1 and M1 and asthma risk in 10,000 individuals and in meta-analysis
Norskov, M., Dahl, Morten & Tybjærg-Hansen, Anne, 1 Sep 2013.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Total and cause-specific mortality by elevated transferrin saturation and hemochromatosis genotype in individuals with diabetes - two general population studies
Ellervik, Christina, Mandrup-Poulsen, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Oct 2013, In: Diabetes Care. 37, 2, p. 444-452 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Endogenous sex hormones and risk of venous thromboembolism in women and men
Holmegard, H. N., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Benn, Marianne, 2014, In: Journal of Thrombosis and Haemostasis. 12, 3, p. 297-305 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomet i kardiologien
Bundgård, Henning, Diness, Birgitte Rode, Tfelt-Hansen, Jacob, Henriksen, F. L., Eschen, O., Skovby, F., Havndrup, O., Jensen, H. K. & Tybjærg-Hansen, Anne, 2014, In: Ugeskrift for Laeger. 176, 46, 5 p., V06140376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low Nonfasting Triglycerides and Reduced All-Cause Mortality: A Mendelian Randomization Study
Thomsen, M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2014, In: Clinical Chemistry. 60, 5, p. 737-746 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2
Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease
Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2014, In: Journal of the American College of Cardiology. 63, 20, p. 2121-2128 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 11 Feb 2014, In: Journal of the American College of Cardiology. 63, 5, p. 470-477 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study
Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 4 Mar 2014, In: Circulation Research. 129, 9, p. 990-998 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Kozlitina, J., Smagris, E., Stender, Stefan, Nordestgaard, Børge, Zhou, H. H., Tybjærg-Hansen, Anne, Vogt, T. F., Hobbs, H. H. & Cohen, J. C., Apr 2014, In: Nature Genetics. 46, 4, p. 352-356 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Jørgensen, A. B., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jul 2014, In: New England Journal of Medicine. 371, 1, p. 32-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management
Hegele, R. A., Ginsberg, H. N., Chapman, M. J., Nordestgaard, B. G., Kuivenhoven, J. A., Averna, M., Borén, J., Bruckert, E., Catapano, A. L., Descamps, O. S., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Masana, L., Pajukanta, P., Parhofer, K. G., Raal, F. J., Ray, K. K., Santos, R. D., Stalenhoef, A. F. H. & 6 others, , Aug 2014, In: The Lancet Diabetes & Endocrinology. 2, 8, p. 655-666 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society
Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G. F., Averna, M., Boileau, C., Borén, J., Catapano, A. L., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 11 others, , 21 Aug 2014, In: European Heart Journal. 35, 32, p. 2146-2157 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals
Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study
Lusk, C. M., Dyson, G., Clark, A. G., Ballantyne, C. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Boerwinkle, E. & Sing, C. F., Sep 2014, In: Human Genetics. 133, 9, p. 1105-1116 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease
Holmes, M. V., Frikke-Schmidt, R., Melis, D., Luben, R., Asselbergs, F. W., Boer, J. M. A., Cooper, J., Palmen, J., Horvat, P., Engmann, J., Li, K-W., Onland-Moret, N. C., Hofker, M. H., Kumari, M., Keating, B. J., Hubacek, J. A., Adamkova, V., Kubinova, R., Bobak, M., Khaw, K-T. & 6 others, , Nov 2014, In: Atherosclerosis. 237, 1, p. 5-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Total and cause-specific mortality by moderately and markedly increased ferritin concentrations: general population study and metaanalysis
Ellervik, Christina, Marott, J. L., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, Nov 2014, In: Clinical Chemistry. 60, 11, p. 1419-1428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subgroups at high risk for ischaemic heart disease:identification and validation in 67 000 individuals from the general population
Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dyson, G., Haase, C. L., Benn, Marianne, Nordestgaard, Børge & Sing, C. F., 2015, In: International Journal of Epidemiology. 44, 1, p. 117-128 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The UK10K project identifies rare variants in health and disease
Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E. & 319 others, , 2015, In: Nature. 526, 7571, p. 82-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, , 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of dementia in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease
Varbo, A., Benn, Marianne, Smith, G. D., Timpson, N. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2015, In: Circulation Research. 116, 4, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women
Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Do, R., Stitziel, N. O., Won, H-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R. & 31 others, , 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Novel genes in LDL metabolism: a comprehensive overview
Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease
Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study
Haase, C. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Sep 2015, In: Diabetes. 64, 9, p. 3328-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation in NPC1L1 and Risk of Gallstone Disease
Lauridsen, B. K., Stender, S. & Tybjærg-Hansen, Anne, 1 Sep 2015, In: Journal of the American College of Cardiology. 66, 9, p. 1086 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L. & 13 others, , 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Sex Hormones and Ischemic Stroke: A Prospective Cohort Study and Meta-Analyses
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Jan 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 1, p. 69-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications
Christoffersen, M. & Tybjærg-Hansen, Anne, Jan 2016, In: Ageing Research Reviews. 25, p. 24-41 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts
Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to the Letter: Response to "Use of biomarkers to identify new drug targets and to predict risk of cardiometabolic outcomes" by Abasi A., et al
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Feb 2016, In: The Journal of clinical endocrinology and metabolism. 101, 2, p. L22-L23Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genetics of Coronary Artery Disease
McPherson, R. & Tybjærg-Hansen, Anne, 18 Feb 2016, In: Circulation Research. 118, 4, p. 564-578 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Data in Brief. 6, p. 923-932 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
CHD Exome+ Consortium, C. E. C., CARDIoGRAM Exome Consortium, C. E. C. & Global Lipids Genetics Consortium, G. L. G. C., 11 Mar 2016, In: Science (New York, N.Y.). 351, 6278, p. 1166-71 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using human genetics to predict the effects and side-effects of drugs
Stender, S. & Tybjærg-Hansen, Anne, Apr 2016, In: Current Opinion in Lipidology. 27, 2, p. 105-111 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population
Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Change in Body Mass Index Associated With Lowest Mortality in Denmark, 1976-2013
Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 10 May 2016, In: JAMA - Journal of the American Medical Association. 315, 18, p. 1989-1996 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Sialylation Pathway and Coronary Artery Disease
Tybjærg-Hansen, Anne, 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2169-2171 3 p.Research output: Contribution to journal › Editorial › Research
- Published
High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Components of the Metabolic Syndrome and Risk of Type 2 Diabetes
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies
Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J. & 35 others, , Aug 2016, In: Gastroenterology. 151, 2, 351 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BODY MASS INDEX AND MORTALITY OVER 3 DECADES
Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High body mass index and cancer risk
Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis
Langsted, A., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne & Kamstrup, P. R., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3281-3287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)
Yang, X., Sethi, A. A., Yanek, L. R., Knapper, C., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Becker, D. M., Mathias, R. A., Remaley, A. T. & Becker, L. C., Oct 2016, In: Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using Human Genetics to Predict the Effects and Side Effects of Lipoprotein(a) Lowering Drugs
Tybjærg-Hansen, Anne, Dec 2016, In: Journal of the American College of Cardiology. 68, 25, p. 2773-2775 3 p.Research output: Contribution to journal › Comment/debate › Research
- 2017
- Published
Blood Chimerism in Dizygotic Monochorionic Twins During 5 Years Observation
Dziegiel, Morten Hanefeld, Hansen, M. H., Haedersdal, S., Barrett, A. N., Rieneck, K., Main, Katharina Maria, Tybjærg-Hansen, Anne & Clausen, F. B., 2017, In: American Journal of Transplantation. 17, 10, p. 2728-2732Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W. K., Young, R., Paul, D. S., Waite, L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H-H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 36 others, , 2017, In: Nature Genetics. 49, p. 1113-1119Research output: Contribution to journal › Letter › Research › peer-review
- Published
Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer
Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses
Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study
Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Stender, S., Kozlitina, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Hobbs, H. H. & Cohen, J. C., Jun 2017, In: Nature Genetics. 49, 6, p. 842-847 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. J., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 31 others, , 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 865-884 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index and risk of Alzheimer's disease: A mendelian randomization study of 399,536 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jul 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2310-2320 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
Dewey, F. E., Gusarova, V., Dunbar, R. L., O'Dushlaine, C. T., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., Leader, J. B., Murray, M. F., Ritchie, M. D., Kirchner, H. L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N. & 37 others, , Jul 2017, In: New England Journal of Medicine. 377, 3, p. 211-221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of APOE ε Genotype on Lipoprotein(a) and the Associated Risk of Myocardial Infarction and Aortic Valve Stenosis
Kritharides, L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Kamstrup, P. R. & Afzal, Shoaib, 1 Sep 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 9, p. 3390-3399 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation in GSTP1, Lung Function, Risk of Lung Cancer, and Mortality
Nørskov, M. S., Dahl, Morten & Tybjærg-Hansen, Anne, Nov 2017, In: Journal of Thoracic Oncology. 12, 11, p. 1664-1672 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2018
- Published
ABCA7 and risk of dementia and vascular disease in the Danish population
Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals
Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in lipid-lowering therapy through gene-silencing technologies
Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272Research output: Contribution to journal › Review › Research › peer-review
- Published
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P. & 61 others, , 2018, In: Nature Communications. 9, 1, 2252.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease
Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals
Lauridsen, B. K., Stender, Steen, zwp671, zwp671, Kofoed, Klaus Fuglsang, Køber, Lars Valeur, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 5, p. 385-393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans
Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Marco, M. D., Stevens, C. A. T., Akram, A., Freiberger, T., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar Salinas, C. A., Al-Khnifsawi, M., Alkindi, F. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 248 others, , 2018, In: Atherosclerosis. 277, p. 234-255 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride
Stender, S., Smagris, E., Lauridsen, B. K., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Tybjærg-Hansen, Anne, Pennacchio, L. A., Dickel, D. E., Cohen, J. C. & Hobbs, H. H., 2018, In: Hepatology. 67, 6, p. 2182-2195 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to: liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease
Stender, S. & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 36, p. 3399Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies
Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, , 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, , Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Blood–brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals
Juul Rasmussen, I., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2019, In: European Journal of Epidemiology. 34, 6, p. 579-590 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal Associations in Type 2 Diabetes Development
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 4, p. 1313-1324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study
Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies
Pennells, L., Kaptoge, S., Wood, A., Sweeting, M., Zhao, X., White, I., Burgess, S., Willeit, P., Bolton, T., Moons, K. G. M., van der Schouw, Y. T., Selmer, R., Khaw, K-T., Gudnason, V., Assmann, G., Amouyel, P., Salomaa, V., Kivimaki, M., Nordestgaard, B. G., Blaha, M. J. & 255 others, , 2019, In: European Heart Journal. 40, 7, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 498-514Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
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