Anne Tybjærg-Hansen
Clinical Professor
- 2024
- E-pub ahead of print
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
DBDS Genomic Consortium, D. G. C., 2024, (E-pub ahead of print) In: Nature Genetics. 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
APOE and vascular disease: Sequencing and genotyping in general population cohorts
Rasmussen, Katrine Laura, Luo, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Atherosclerosis. 385, 9 p., 117218.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration
Rasmussen, Katrine Laura, Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2023, In: JAMA Ophthalmology. 141, 1, p. 13-21 9 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Cholesteryl Ester Transfer Protein Inhibitors and Access to the Retina in Age-Related Macular Degeneration-Reply
Nordestgaard, L. T., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: JAMA Cardiology. 8, 2, p. 206-207Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Genetic risk of fatty liver disease and mortality in the general population: A Mendelian randomization study
Gellert-Kristensen, H., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ghouse, Jonas, Fuchs, A., Kühl, J. T., Sigvardsen, P. E., Kofoed, Klaus Fuglsang & Stender, S., 2023, In: Liver International. 43, 9, p. 1955-1965 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Journal of Epidemiology. 38, 9, p. 985-994 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High fat in blood and body and increased risk of clinically diagnosed non-alcoholic fatty liver disease in 105,981 individuals
Kyhl, L. K., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Nielsen, S. F., 2023, In: Atherosclerosis. 376, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutrophil counts and cardiovascular disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies
Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 5, p. 525-536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals
Dalila, N., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: Atherosclerosis. 376, p. 26-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life
Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Triglyceride-rich remnant lipoproteins are more atherogenic than LDL per particle: is this important?
Tybjærg-Hansen, Anne, Nordestgaard, Børge & Christoffersen, M., 2023, In: European Heart Journal. 44, 39, p. 4196-4198 3 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society
Roeters Van Lennep, J. E., Tokgözoǧlu, L. S., Badimon, L., Dumanski, S. M., Gulati, M., Hess, C. N., Holven, K. B., Kavousi, M., Kaylkçloǧlu, M., Lutgens, E., Michos, E. D., Prescott, Eva, Stock, J. K., Tybjærg-Hansen, Anne, Wermer, M. J. H. & Benn, Marianne, 2023, In: European Heart Journal. 44, 39, p. 4157-4173 17 p.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma
Praveen, K., Patel, G. C., Gurski, L., Ayer, A. H., Persaud, T., Still, M. D., Miloscio, L., Van Zyl, T., Di Gioia, S. A., Brumpton, B., Krebs, K., Åsvold, B. O., Chen, E., Chavali, V. R. M., Fury, W., Gudiseva, H. V., Hyde, S., Jorgenson, E., Lefebvre, S., Li, D. & 37 others, , 2022, In: Communications Biology . 5, 15 p., 1051.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population
Seidelin, A. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Yaghootkar, H. & Stender, Stefan, 2022, In: Hepatology International. 16, 3, p. 702-711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adherence to dietary guidelines and risk of dementia: a prospective cohort study of 94 184 individuals
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Epidemiology and Psychiatric Sciences. 31, e71.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood Leukocyte Counts in Alzheimer Disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 10, 14 p., E2235648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-reactive protein levels and risk of dementia — Observational and genetic studies of 111,242 individuals from the general population
Hegazy, S. H., Thomassen, J. Q., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 11, p. 2262-2271 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function
Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., Van Den Bosch, M. T., Teasdale, J. E., Jones, M., Bond, M., Harper, M. T., Falk, L., Groom, A., Hazell, G. G. J., Paternoster, L., Munafò, M. R., Nordestgaard, B. G., Tybjærg-Hansen, A., Bojesen, S. E., Relton, C., Min, J. L. & 4 others, , 2022, In: Circulation Research. 130, 3, p. 384-400 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of diet on ten-year absolute cardiovascular risk in a prospective cohort of 94 321 individuals: A tool for implementation of healthy diets
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: The Lancet Regional Health - Europe. 19, 100419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) Levels at Birth and in Early Childhood: The COMPARE Study
Strandkjær, N., Hansen, M. K., Nielsen, S. T., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Tabor, Ann, Bundgård, Henning, Iversen, Kasper & Kamstrup, P. R., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. 324-335 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term Benefits and Harms Associated with Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population
Nordestgaard, L. T., Christoffersen, M., Lauridsen, B. K., Afzal, Shoaib, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 1, p. 55-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macular Degeneration and CETP Inhibition-Reply
Nordestgaard, L. T., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 7, p. 775-776 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses
Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A. M., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S. & 30 others, , 2022, In: Circulation. 146, 20, p. 1507-1517 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals
Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease
Frikke-Schmidt, Ruth, Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Thomassen, J. Q., 2022, In: Alzheimer's and Dementia. 18, 12, p. 2734-2735Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Pharmacogenetics-guided CETP inhibition: an open question?
Tybjærg-Hansen, Anne, Nordestgaard, L. T. & Christoffersen, M., 2022, In: European Heart Journal. 43, 39, p. 3957-3959 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals
Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies
Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome
Zanoni, P., Panteloglou, G., Othman, A., Haas, J. T., Meier, R., Rimbert, A., Futema, M., Khalil, Y. A., Norrelykke, S. F., Rzepiela, A. J., Stoma, S., Stebler, M., Van Dijk, F., Wijers, M., Wolters, J. C., Dalila, N., Huijkman, N. C. A., Smit, M., Gallo, A., Carreau, V. & 26 others, , 2022, In: Circulation Research. 130, 1, p. 80-95 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to “Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk”
Luo, J., Thomassen, J. Q., Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 10, p. 2007-2009 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Statin Eligibility for Primary Prevention of Cardiovascular Disease According to 2021 European Prevention Guidelines Compared with Other International Guidelines
Mortensen, M. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: JAMA Cardiology. 7, 8, p. 836-843Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stroke genetics informs drug discovery and risk prediction across ancestries
Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 45 others, , 2022, In: Nature. 611, 7934, p. 115-123 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The European Heart Journal: fulfilling the mission
Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C. & Tybjærg-Hansen, Anne, 2022, In: European Heart Journal. 43, 23, p. 2181-2184 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
Motazedi, E., Cheng, W., Thomassen, J. Q., Frei, O., Rongve, A., Athanasiu, L., Bahrami, S., Shadrin, A., Ulstein, I., Stordal, E., Brækhus, A., Saltvedt, I., Sando, S. B., O'Connell, K. S., Hindley, G., Van Der Meer, D., Bergh, S., Nordestgaard, B. G., Tybjærg-Hansen, A., Brthen, G. & 10 others, , 2022, In: Journal of Alzheimer's Disease. 88, 4, p. 1533-1544Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile
Rimbert, A., Yeung, M. W., Dalila, N., Thio, C. H. L., Yu, H., Loaiza, N., Oldoni, F., van der Graaf, A., Wang, S., Said, M. A., Blauw, L. L., Girardeau, A., Bray, L., Caillaud, A., Bloks, V. W., Marrec, M., Mouli, P., Rensen, P. C. N., van de Sluis, B., Snieder, H. & 6 others, , 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 10, p. 1262-1271 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
EADB contributors, E. C., The GR@ACE study group, T. G. S. G., DEGESCO consortium, D. C., IGAP (ADGC, CHARGE, EADI, GERAD), I. (. C. E. G. & PGC-ALZ consortia, P. C., Dec 2021, In: Nature Communications. 12, 1, 16 p., 3417.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated Apolipoprotein A1 and HDL Cholesterol Associated with Age-related Macular Degeneration: 2 Population Cohorts
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 16 Jun 2021, In: The Journal of clinical endocrinology and metabolism. 106, 7, p. e2749-e2758 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of sixteen serological SARS-CoV-2 immunoassays in sixteen clinical laboratories
Harritshøj, L. H., Gybel-Brask, M., Afzal, S., Kamstrup, P. R., Jørgensen, C. S., Thomsen, M. K., Hilsted, L., Friis-Hansen, L., Szecsi, P. B., Pedersen, L., Nielsen, L., Hansen, C. B., Garred, P., Korsholm, T-L., Mikkelsen, S., Nielsen, K. O., Møller, B. K., Hansen, A. T., Iversen, K. K., Nielsen, P. B. & 18 others, , 11 Feb 2021, In: Journal of Clinical Microbiology. 59, 5, e02596-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
EU-PNAFLD Investigators, E. I. & GOLD Consortium, G. C., Jan 2021, In: Journal of Hepatology. 74, 1, p. 20-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Low Plasma Transthyretin Concentration with Risk of Heart Failure in the General Population
Greve, A. M., Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2021, In: JAMA Cardiology. 6, 3, p. 258-266Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common genetic variation in mc4r does not affect atherosclerotic plaque phenotypes and cardiovascular disease outcomes
Blauw, L. L., Noordam, R., van der Laan, S. W., Trompet, S., Kooijman, S., van Heemst, D., Jukema, J. W., van Setten, J., de Borst, G. J., Tybjærg-Hansen, Anne, Pasterkamp, G., Berbée, J. F. P. & Rensen, P. C. N., 2021, In: Journal of Clinical Medicine. 10, 5, 12 p., 932.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variants Associated With Increased Plasma Levels of Triglycerides, via Effects on the Lipoprotein Lipase Pathway, Increase Risk of Acute Pancreatitis
Hansen, S. E. J., Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Clinical Gastroenterology and Hepatology. 19, 8, p. 1652-1660.e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in ABCA1 and risk of all-cause dementia, age-related macular degeneration, and ischemic heart disease
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Atherosclerosis. 331, p. E38-E39 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Stevens, C. A. T., Lyons, A. R. M., Dharmayat, K. I., Freiberger, T., Hovingh, G. K., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar-Salinas, C. A., Alhabib, K. F., Alkhnifsawi, M., Almahmeed, W., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 31 others, , 2021, In: The Lancet. 398, 10312, p. 1713-1725 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis
Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Trinder, M., Wang, Y., Madsen, C. M., Ponomarev, T., Bohunek, L., Daisley, B. A., Kong, H. J., Blauw, L. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Wurfel, M. M., Russell, J. A., Walley, K. R., Rensen, P. C. N., Boyd, J. H. & Brunham, L. R., 2021, In: Circulation. 143, 9, p. 921–934Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low and high pancreatic amylase is associated with pancreatic cancer and chronic pancreatitis
Hansen, S. E. J., Langsted, A., Varbo, A., Madsen, C. M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: European Journal of Epidemiology. 36, p. 975–984Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals
Thomassen, J. Q., Tolstrup, J. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 6, p. 899-911 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk scores: how much do they add?
Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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