Anders Skov Kristensen

Anders Skov Kristensen

Associate Professor


  1. 2024
  2. Published

    Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

    Bay, Yasmin, Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, Anders Skov, Boesen, T., Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2024, In: FEBS Journal. 291, 7, p. 1506-1529

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2

    Bay, Yasmin, Egeberg Jeppesen, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Pickering, Darryl S, Kristensen, Anders Skov & Kastrup, Jette Sandholm Jensen, 2024, In: FEBS Letters. 598, 7, p. 743-757

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes

    Rinaldi, B., Bayat, A., Zachariassen, L. G., Sun, J., Ge, Y., Zhao, D., Bonde, K., Madsen, L. H., Awad, I. A. A., Bagiran, D., Sbeih, A., Shah, S. M., El-sayed, S., Lyngby, S. M., Pedersen, M. G., Stenum-berg, C., Walker, L. C., Krey, I., Delahaye-duriez, A., Emrick, L. T. & 67 others, Sully, K., Murali, C. N., Burrage, L. C., Plaud Gonzalez, J. A., Parnes, M., Friedman, J., Isidor, B., Lefranc, J., Redon, S., Heron, D., Mignot, C., Keren, B., Fradin, M., Dubourg, C., Mercier, S., Besnard, T., Cogne, B., Deb, W., Rivier, C., Milani, D., Bedeschi, M. F., Di Napoli, C., Grilli, F., Marchisio, P., Koudijs, S., Veenma, D., Argilli, E., Lynch, S. A., Au, P. Y. B., Ayala Valenzuela, F. E., Brown, C., Masser-frye, D., Jones, M., Patron Romero, L., Li, W. L., Thorpe, E., Hecher, L., Johannsen, J., Denecke, J., Mcniven, V., Szuto, A., Wakeling, E., Cruz, V., Sency, V., Wang, H., Piard, J., Kortüm, F., Herget, T., Bierhals, T., Condell, A., Zeev, B. B., Kaur, S., Christodoulou, J., Piton, A., Zweier, C., Kraus, C., Micalizzi, A., Trivisano, M., Specchio, N., Lesca, G., Møller, R. S., Tümer, Asuman Zeynep, Musgaard, M., Gerard, B., Lemke, J. R., Shi, Y. S. & Kristensen, Anders Skov, 2024, (E-pub ahead of print) In: Brain.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Nielsen, B., Bay, Yasmin, Kristensen, Anders Skov, Hinkkanen, M., Szczepańska, K., Karcz, T., Latacz, G., Johansen, Tommy Nørskov & Szymanska, E. M., 2023, In: ChemMedChem. 18, 18, 15 p., e202300278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3

    Hackney, Celeste Menuet, Flórez Salcedo, P., Mueller, E., Koch, Thomas Lund, Kjelgaard, L. D., Watkins, M., Zachariassen, L., Tuelund, P. S., McArthur, J. R., Adams, D. J., Kristensen, Anders Skov, Olivera, B., Finol-Urdaneta, R. K., Safavi-Hemami, H., Morth, J. P. & Ellgaard, Lars, 2023, In: PLOS Biology. 21, 8, 32 p., e3002217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes

    Rinaldi, B., Bayat, A., Zachariassen, L. G., Sun, J-H., Ge, Y-H., Zhao, D., Bonde, K., Madsen, L. H., Awad, I. A. A., Bagiran, D., Sbeih, A., Shah, S. M., El-Sayed, S., Lyngby, S. M., Pedersen, M. G., Stenum-Berg, C., Walker, L. C., Krey, I., Delahaye-Duriez, A., Emrick, L. T. & 67 others, Sully, K., Murali, C. N., Burrage, L. C., Plaud Gonzalez, J. A., Parnes, M., Friedman, J., Isidor, B., Lefranc, J., Redon, S., Heron, D., Mignot, C., Keren, B., Fradin, M., Dubourg, C., Mercier, S., Besnard, T., Cogne, B., Deb, W., Rivier, C., Milani, D., Bedeschi, M. F., Di Napoli, C., Grilli, F., Marchisio, P., Koudijs, S., Veenma, D., Argilli, E., Lynch, S. A., Au, P. Y. B., Ayala Valenzuela, F. E., Brown, C., Masser-Frye, D., Jones, M., Patron Romero, L., Li, W. L., Thorpe, E., Hecher, L., Johannsen, J., Denecke, J., McNiven, V., Szuto, A., Wakeling, E., Cruz, V., Sency, V., Wang, H., Piard, J., Kortüm, F., Herget, T., Bierhals, T., Condell, A., Zeev, B. B., Kaur, S., Christodoulou, J., Piton, A., Zweier, C., Kraus, C., Micalizzi, A., Trivisano, M., Specchio, N., Lesca, G., Møller, R. S., Tümer, Asuman Zeynep, Musgaard, M., Gerard, B., Lemke, J. R., Shi, Y. S. & Kristensen, Anders Skov, 1 Dec 2023, (E-pub ahead of print) In: Brain : a journal of neurology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2022
  10. Published

    Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, Anders A., Nielsen, Birgitte, Bay, Yasmin, Kristensen, Anders Skov, Johansen, Tommy Nørskov, Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome

    Ismail, V., Zachariassen, L. G., Godwin, A., Sahakian, M., Ellard, S., Stals, K. L., Baple, E., Brown, K. T., Foulds, N., Wheway, G., Parker, M. O., Lyngby, Signe Meisner, Pedersen, M. G., Desir, J., Bayat, Allan, Musgaard, M., Guille, M., Kristensen, Anders Skov & Baralle, D., 7 Jul 2022, In: American Journal of Human Genetics. 109, 7, p. 1217-1241 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome

    Ismail, V., Zachariassen, L. G., Godwin, A., Sahakian, M., Ellard, S., Stals, K. L., Baple, E., Brown, K. T., Foulds, N., Wheway, G., Parker, M. O., Lyngby, S. M., Pedersen, M. G., Desir, J., Bayat, A., Musgaard, M., Guille, M., Kristensen, Anders Skov & Baralle, D., 2022, In: American Journal of Human Genetics. 109, 7, p. 1217-1241

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2019
  14. Published

    Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry

    Munro, L., Ladefoged, L. K., Padmanathan, V., Andersen, S., Schiott, B. & Kristensen, Anders Skov, 1 Dec 2019, In: Molecular Pharmacology. 96, 6, p. 720-734

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 1302186