Two variance results in population genetics theory
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Two variance results in population genetics theory. / Ewens, Warren J.; Choudhury, Arindam Roy; Lewontin, Richard C.; Wiuf, Carsten.
I: Mathematical Population Studies, Bind 14, Nr. 2, 01.04.2007, s. 93-110.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Two variance results in population genetics theory
AU - Ewens, Warren J.
AU - Choudhury, Arindam Roy
AU - Lewontin, Richard C.
AU - Wiuf, Carsten
PY - 2007/4/1
Y1 - 2007/4/1
N2 - The assessment of the degree of genetic variation in a natural population, and the nature of that variation, is of central importance in both theoretical and applied population studies. Two "variance" results in population genetics theory are presented. For the first, expressions are found for the expected difference in the estimates of genetic variation in a population obtained by two investigators sampling from the same population in the same generation. The second result concerns the question of whether the degree of genetic variation in a population is best estimated by using the number of alleles observed in a sample of genes or by the number of polymorphic sites observed in the sample. For some combinations of the actual degree of variation and the sample size the former is preferred while for other combinations the latter is preferred. The reason for this is discussed.
AB - The assessment of the degree of genetic variation in a natural population, and the nature of that variation, is of central importance in both theoretical and applied population studies. Two "variance" results in population genetics theory are presented. For the first, expressions are found for the expected difference in the estimates of genetic variation in a population obtained by two investigators sampling from the same population in the same generation. The second result concerns the question of whether the degree of genetic variation in a population is best estimated by using the number of alleles observed in a sample of genes or by the number of polymorphic sites observed in the sample. For some combinations of the actual degree of variation and the sample size the former is preferred while for other combinations the latter is preferred. The reason for this is discussed.
KW - Alleles
KW - Estimation
KW - Genetics
KW - Optimality
KW - Sites
KW - Variance
UR - http://www.scopus.com/inward/record.url?scp=34247892231&partnerID=8YFLogxK
U2 - 10.1080/08898480701298376
DO - 10.1080/08898480701298376
M3 - Journal article
AN - SCOPUS:34247892231
VL - 14
SP - 93
EP - 110
JO - Mathematical Population Studies
JF - Mathematical Population Studies
SN - 0889-8480
IS - 2
ER -
ID: 203903929