Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat
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Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat. / Poulsen, Steen Seier; Thulesen, J; Christensen, L; Nexo, E; Thim, L.
I: Gut, Bind 45, Nr. 4, 01.10.1999, s. 516-22.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Metabolism of oral trefoil factor 2 (TFF2) and the effect of oral and parenteral TFF2 on gastric and duodenal ulcer healing in the rat
AU - Poulsen, Steen Seier
AU - Thulesen, J
AU - Christensen, L
AU - Nexo, E
AU - Thim, L
PY - 1999/10/1
Y1 - 1999/10/1
N2 - Trefoil factors (TFFs) are peptides produced by mucus-secreting cells in the gastrointestinal tract. A functional association between these peptides and mucus, leading to stabilisation of the viscoelastic gel overlying the epithelia, has been suggested. Both oral and parenteral administration of the peptides increase the resistance of the gastric mucosa.
AB - Trefoil factors (TFFs) are peptides produced by mucus-secreting cells in the gastrointestinal tract. A functional association between these peptides and mucus, leading to stabilisation of the viscoelastic gel overlying the epithelia, has been suggested. Both oral and parenteral administration of the peptides increase the resistance of the gastric mucosa.
KW - Administration, Cutaneous
KW - Administration, Oral
KW - Animals
KW - Digestive System
KW - Duodenal Ulcer
KW - Female
KW - Growth Substances
KW - Mucins
KW - Muscle Proteins
KW - Neuropeptides
KW - Peptides
KW - Rats
KW - Rats, Sprague-Dawley
KW - Stomach Ulcer
KW - Wound Healing
M3 - Journal article
C2 - 10486358
VL - 45
SP - 516
EP - 522
JO - Gut
JF - Gut
SN - 0017-5749
IS - 4
ER -
ID: 33793331