Glucagon regulation of energy expenditure
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Glucagon regulation of energy expenditure. / Kleinert, Maximilian; Sachs, Stephan; Habegger, Kirk M; Hofmann, Susanna M; Müller, Timo D.
I: International Journal of Molecular Sciences, Bind 20, Nr. 21, 5407, 2019.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Glucagon regulation of energy expenditure
AU - Kleinert, Maximilian
AU - Sachs, Stephan
AU - Habegger, Kirk M
AU - Hofmann, Susanna M
AU - Müller, Timo D
N1 - CURIS 2019 NEXS 368
PY - 2019
Y1 - 2019
N2 - Glucagon’s ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon’s thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.
AB - Glucagon’s ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon’s thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.
KW - Brown adipose tissue
KW - Energy expenditure
KW - FGF21
KW - Glucagon
KW - Obesity
KW - Pharmacology
U2 - 10.3390/ijms20215407
DO - 10.3390/ijms20215407
M3 - Review
C2 - 31671603
AN - SCOPUS:85074370668
VL - 20
JO - International Journal of Molecular Sciences (CD-ROM)
JF - International Journal of Molecular Sciences (CD-ROM)
SN - 1424-6783
IS - 21
M1 - 5407
ER -
ID: 230739280