Conditional genealogies and the age of a neutral mutant
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Conditional genealogies and the age of a neutral mutant. / Wiuf, Carsten; Donnelly, Peter.
I: Theoretical Population Biology, Bind 56, Nr. 2, 01.01.1999, s. 183-201.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Conditional genealogies and the age of a neutral mutant
AU - Wiuf, Carsten
AU - Donnelly, Peter
PY - 1999/1/1
Y1 - 1999/1/1
N2 - This paper is concerned with the structure of the genealogy of a sample in which it is observed that some subset of chromosomes carries a particular mutation, assumed to have arisen uniquely in the history of the population. A rigorous theoretical study of this conditional genealogy is given using coalescent methods. Particular results include the mean, variance, and density of the age of the mutation conditional on its frequency in the sample. Most of the development relates to populations of constant size, but we discuss the extension to populations which have grown exponentially to their present size.
AB - This paper is concerned with the structure of the genealogy of a sample in which it is observed that some subset of chromosomes carries a particular mutation, assumed to have arisen uniquely in the history of the population. A rigorous theoretical study of this conditional genealogy is given using coalescent methods. Particular results include the mean, variance, and density of the age of the mutation conditional on its frequency in the sample. Most of the development relates to populations of constant size, but we discuss the extension to populations which have grown exponentially to their present size.
KW - Age of allele
KW - Coalescent model
KW - Conditional genealogies
UR - http://www.scopus.com/inward/record.url?scp=0033213012&partnerID=8YFLogxK
U2 - 10.1006/tpbi.1998.1411
DO - 10.1006/tpbi.1998.1411
M3 - Journal article
C2 - 10544068
AN - SCOPUS:0033213012
VL - 56
SP - 183
EP - 201
JO - Theoretical Population Biology
JF - Theoretical Population Biology
SN - 0040-5809
IS - 2
ER -
ID: 203901472