Adrenergic effects on secretion of amylase from the rat salivary glands
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Adrenergic effects on secretion of amylase from the rat salivary glands. / Poulsen, Steen Seier; Nexø, Ebba.
I: Digestion, Bind 41, Nr. 1, 1988, s. 34-8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Adrenergic effects on secretion of amylase from the rat salivary glands
AU - Poulsen, Steen Seier
AU - Nexø, Ebba
PY - 1988
Y1 - 1988
N2 - The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alpha- and beta-adrenergic antagonists as well as noradrenaline and isoproterenol showed that secretion of salivary amylase is predominantly mediated by stimulation of beta-adrenergic receptors, especially of the beta 1-subtype. Investigation of the isoenzyme pattern in saliva, pancreatic juice and serum demonstrated that the major component in serum is salivary amylase. This study has shown that beta-adrenergic agents stimulate secretion of amylase from the salivary glands in rats. Though the secretion is mainly exocrine small amounts of amylase is found in serum, which seems to originate from the salivary glands.
AB - The present study was undertaken to investigate the effect of adrenergic agents on secretion of amylase from the salivary glands in vivo. Saliva was collected from the distal oesophagus in conscious rats. Adrenaline increased the concentration of amylase in saliva and serum significantly. The result of infusion of alpha- and beta-adrenergic antagonists as well as noradrenaline and isoproterenol showed that secretion of salivary amylase is predominantly mediated by stimulation of beta-adrenergic receptors, especially of the beta 1-subtype. Investigation of the isoenzyme pattern in saliva, pancreatic juice and serum demonstrated that the major component in serum is salivary amylase. This study has shown that beta-adrenergic agents stimulate secretion of amylase from the salivary glands in rats. Though the secretion is mainly exocrine small amounts of amylase is found in serum, which seems to originate from the salivary glands.
KW - Amylases
KW - Animals
KW - Atenolol
KW - Epinephrine
KW - Isoenzymes
KW - Isoproterenol
KW - Male
KW - Norepinephrine
KW - Phenoxybenzamine
KW - Propranolol
KW - Rats
KW - Rats, Inbred Strains
KW - Salivary Glands
KW - Sympathomimetics
M3 - Journal article
C2 - 2462520
VL - 41
SP - 34
EP - 38
JO - Digestion
JF - Digestion
SN - 0012-2823
IS - 1
ER -
ID: 47488426