Acute antidepressant drug administration and autobiographical memory recall: a functional magnetic resonance imaging study

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Acute antidepressant drug administration and autobiographical memory recall : a functional magnetic resonance imaging study. / Papadatou-Pastou, Marietta; Miskowiak, Kamilla W; Williams, J Mark G; Harmer, Catherine J; Reinecke, Andrea.

I: Experimental and Clinical Psychopharmacology, Bind 20, Nr. 5, 10.2012, s. 364-72.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Papadatou-Pastou, M, Miskowiak, KW, Williams, JMG, Harmer, CJ & Reinecke, A 2012, 'Acute antidepressant drug administration and autobiographical memory recall: a functional magnetic resonance imaging study', Experimental and Clinical Psychopharmacology, bind 20, nr. 5, s. 364-72. https://doi.org/10.1037/a0027969

APA

Papadatou-Pastou, M., Miskowiak, K. W., Williams, J. M. G., Harmer, C. J., & Reinecke, A. (2012). Acute antidepressant drug administration and autobiographical memory recall: a functional magnetic resonance imaging study. Experimental and Clinical Psychopharmacology, 20(5), 364-72. https://doi.org/10.1037/a0027969

Vancouver

Papadatou-Pastou M, Miskowiak KW, Williams JMG, Harmer CJ, Reinecke A. Acute antidepressant drug administration and autobiographical memory recall: a functional magnetic resonance imaging study. Experimental and Clinical Psychopharmacology. 2012 okt.;20(5):364-72. https://doi.org/10.1037/a0027969

Author

Papadatou-Pastou, Marietta ; Miskowiak, Kamilla W ; Williams, J Mark G ; Harmer, Catherine J ; Reinecke, Andrea. / Acute antidepressant drug administration and autobiographical memory recall : a functional magnetic resonance imaging study. I: Experimental and Clinical Psychopharmacology. 2012 ; Bind 20, Nr. 5. s. 364-72.

Bibtex

@article{b199daef4ce94e0f8eaf95fdda176a1a,
title = "Acute antidepressant drug administration and autobiographical memory recall: a functional magnetic resonance imaging study",
abstract = "Antidepressants affect memory and neural responses to emotionally valenced stimuli in healthy volunteers. However, it is unclear whether this extends to autobiographical memory for personally experienced events. The current study investigated the effects of acute administration of the antidepressant reboxetine on emotional autobiographical retrieval in healthy volunteers (14 men, 10 women). Functional magnetic resonance imaging was used in a double-blind between-groups investigation with reboxetine (4 mg) and placebo. Consistent with previous reports using lab-based stimuli, neural activation in the processing of positive versus negative memories was reduced following reboxetine compared with placebo in the left frontal lobe (extending into the insula) and the right superior temporal gyrus. This was paired with increased memory speed in volunteers given reboxetine versus placebo. The effect of reboxetine on emotional memory extends to recall of personally experienced events. Such effects may be relevant to the cognitive improvements found with recovery from depression and with the mechanism of action of contemporary antidepressant drugs.",
keywords = "Adult, Antidepressive Agents, Brain Mapping, Double-Blind Method, Female, Frontal Lobe, Humans, Magnetic Resonance Imaging, Male, Memory, Episodic, Mental Recall, Morpholines, Temporal Lobe, Young Adult, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",
author = "Marietta Papadatou-Pastou and Miskowiak, {Kamilla W} and Williams, {J Mark G} and Harmer, {Catherine J} and Andrea Reinecke",
year = "2012",
month = oct,
doi = "10.1037/a0027969",
language = "English",
volume = "20",
pages = "364--72",
journal = "Experimental and Clinical Psychopharmacology",
issn = "1064-1297",
publisher = "American Psychological Association Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Acute antidepressant drug administration and autobiographical memory recall

T2 - a functional magnetic resonance imaging study

AU - Papadatou-Pastou, Marietta

AU - Miskowiak, Kamilla W

AU - Williams, J Mark G

AU - Harmer, Catherine J

AU - Reinecke, Andrea

PY - 2012/10

Y1 - 2012/10

N2 - Antidepressants affect memory and neural responses to emotionally valenced stimuli in healthy volunteers. However, it is unclear whether this extends to autobiographical memory for personally experienced events. The current study investigated the effects of acute administration of the antidepressant reboxetine on emotional autobiographical retrieval in healthy volunteers (14 men, 10 women). Functional magnetic resonance imaging was used in a double-blind between-groups investigation with reboxetine (4 mg) and placebo. Consistent with previous reports using lab-based stimuli, neural activation in the processing of positive versus negative memories was reduced following reboxetine compared with placebo in the left frontal lobe (extending into the insula) and the right superior temporal gyrus. This was paired with increased memory speed in volunteers given reboxetine versus placebo. The effect of reboxetine on emotional memory extends to recall of personally experienced events. Such effects may be relevant to the cognitive improvements found with recovery from depression and with the mechanism of action of contemporary antidepressant drugs.

AB - Antidepressants affect memory and neural responses to emotionally valenced stimuli in healthy volunteers. However, it is unclear whether this extends to autobiographical memory for personally experienced events. The current study investigated the effects of acute administration of the antidepressant reboxetine on emotional autobiographical retrieval in healthy volunteers (14 men, 10 women). Functional magnetic resonance imaging was used in a double-blind between-groups investigation with reboxetine (4 mg) and placebo. Consistent with previous reports using lab-based stimuli, neural activation in the processing of positive versus negative memories was reduced following reboxetine compared with placebo in the left frontal lobe (extending into the insula) and the right superior temporal gyrus. This was paired with increased memory speed in volunteers given reboxetine versus placebo. The effect of reboxetine on emotional memory extends to recall of personally experienced events. Such effects may be relevant to the cognitive improvements found with recovery from depression and with the mechanism of action of contemporary antidepressant drugs.

KW - Adult

KW - Antidepressive Agents

KW - Brain Mapping

KW - Double-Blind Method

KW - Female

KW - Frontal Lobe

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Memory, Episodic

KW - Mental Recall

KW - Morpholines

KW - Temporal Lobe

KW - Young Adult

KW - Journal Article

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1037/a0027969

DO - 10.1037/a0027969

M3 - Journal article

C2 - 22731734

VL - 20

SP - 364

EP - 372

JO - Experimental and Clinical Psychopharmacology

JF - Experimental and Clinical Psychopharmacology

SN - 1064-1297

IS - 5

ER -

ID: 184777475