Albert J. Kooistra
Lektor
Farmaceutisk Informatik
Universitetsparken 2
2100 København Ø
Albert is an associate professor in Data Science for Drug Design (DSDD) at the University of Copenhagen (DK), where he also heads the Pharmaceutical Data Science team and the Data and Computing Facility.
After a masters in bioinformatics, he obtained his PhD degree in computational medicinal chemistry at the Vrije Universiteit Amsterdam (NL), and subsequently did postdoctoral work in molecular dynamics, structural bioinformatics, and cheminformatics. For his continued work enabling research via scientific databases, he received the 2021 MGMS Frank Blaney award from the Molecular Graphics and Modelling Society.
Research - Network Medicine
The DSDD research group focuses on developing and applying cutting-edge and data-driven technologies to ultimately advance the development of new therapeutics. With expertise in structural bioinformatics, cheminformatics, computer-aided drug discovery & design, research tool/database development and applying machine learning/AI approaches. Albert is also the founder and developer of KLIFS (https://klifs.net), a structural kinase database that is widely used by >1600 researchers every month for kinase and kinase inhibitor research.
Education
Albert has been involved in setting up and teaching a wide range of courses and workshops for highschool, BSc, MSc, and PhD students and life-long-learners. For his work of implementing Virtual Reality in the classroom, he received a faculty-wide educational innovation award in 2017 from the VU University Amsterdam.
Selected courses/workshops:
- AI in Drug Discovery - international PhD course - 50-60 participants
- Hands-on computational Medicinal Chemistry - international PhD course - 20-40 participants
- Big Data, AI/ML in Drug Safety - Life-long learning - 20 participants
- Structure-based Drug Research - MSc course - 30-40 participants
- Pharmaceutical Modeling - MSc course - 10-20 participants
- Digital Core Curriculum (DCC) implementation - Data Science in BSc curriculum - 200+ participtants
Mulige interessekonflikter
Alongside his tenured position at UCPH, Albert has the following roles:
- Co-founder and CTO - Synamics Therapeutics (since 2023)
- Senior Scientific Expert - Kvantify (since 2022)
Udvalgte publikationer
- Udgivet
GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources
Pándy-Szekeres, Gáspár, Caroli, J., Mamyrbekov, A., Kermani, A. A., Keserű, G. M., Kooistra, Albert J. & Gloriam, David E., 2023, I: Nucleic Acids Research. 51, D1, s. D395–D402Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Udgivet
KLIFS: an overhaul after the first 5 years of supporting kinase research
Kanev, G. K., de Graaf, C., Westerman, B. A., de Esch, I. J. P. & Kooistra, Albert J., 2021, I: Nucleic Acids Research. 49, D1, s. D562-D569Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Udgivet
Structure of the class D GPCR Ste2 dimer coupled to two G proteins
Velazhahan, V., Ma, N., Pándy-Szekeres, Gáspár, Kooistra, Albert J., Lee, Y., Gloriam, David E., Vaidehi, N. & Tate, C. G., 2021, I: Nature. 589, s. 148-153 +app 24 ppPublikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The Landscape of Atypical and Eukaryotic Protein Kinases
Kanev, G. K., de Graaf, C., de Esch, I. J. P., Leurs, R., Würdinger, T., Westerman, B. A. & Kooistra, Albert J., nov. 2019, I: Trends in Pharmacological Sciences. 40, 11, s. 818-832 15 s.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Chemical Diversity in the G Protein-Coupled Receptor Superfamily
Vass, M., Kooistra, Albert J., Yang, D., Stevens, R. C., Wang, M. W. & de Graaf, C., 1 maj 2018, I: Trends in Pharmacological Sciences. 39, 5, s. 494-512 19 s.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
ID: 196033213
Flest downloads
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122
downloads
GPCRdb in 2021: integrating GPCR sequence, structure and function
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet -
75
downloads
The Landscape of Atypical and Eukaryotic Protein Kinases
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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71
downloads
KLIFS: an overhaul after the first 5 years of supporting kinase research
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Udgivet