Julien Ochala
Associate Professor - Promotion Programme
- 2018
Defining the contribution of skeletal muscle pyruvate dehydrogenase α1 to exercise performance and insulin action
Svensson, K., Dent, J. R., Tahvilian, S., Martins, V. F., Sathe, A., Ochala, Julien, Patel, M. S. & Schenk, S., Nov 2018, In: American Journal of Physiology - Endocrinology and Metabolism. 315, 5, p. E1034-E1045Research output: Contribution to journal › Journal article › Research › peer-review
Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy
Buono, S., Ross, J. A., Tasfaout, H., Levy, Y., Kretz, C., Tayefeh, L., Matson, J., Guo, S., Kessler, P., Monia, B. P., Bitoun, M., Ochala, Julien, Laporte, J. & Cowling, B. S., 23 Oct 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 11066-11071 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness
Levy, Y., Ross, J. A., Niglas, M., Snetkov, V. A., Lynham, S., Liao, C., Puckelwartz, M. J., Hsu, Y., McNally, E. M., Alsheimer, M., Harridge, S. D., Young, S. G., Fong, L. G., Español, Y., Lopez-Otin, C., Kennedy, B. K., Lowe, D. A. & Ochala, Julien, 4 Oct 2018, In: JCI insight. 3, 19Research output: Contribution to journal › Journal article › Research › peer-review
SIRT1 regulates nuclear number and domain size in skeletal muscle fibers
Ross, J. A., Levy, Y., Svensson, K., Philp, A., Schenk, S. & Ochala, Julien, Sep 2018, In: Journal of Cellular Physiology. 233, 9, p. 7157-7163 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction
Jungbluth, H., Treves, S., Zorzato, F., Sarkozy, A., Ochala, Julien, Sewry, C., Phadke, R., Gautel, M. & Muntoni, F., Mar 2018, In: Nature Reviews. Neurology. 14, 3, p. 151-167 17 p.Research output: Contribution to journal › Review › Research › peer-review
Myostatin inhibition using mrk35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice
Tinklenberg, J. A., Siebers, E. M., Beatka, M. J., Meng, H., Yang, L., Zhang, Z., Ross, J. A., Ochala, Julien, Morris, C., Owens, J. M., Laing, N. G., Nowak, K. J. & Lawlor, M. W., 15 Feb 2018, In: Human Molecular Genetics. 27, 4, p. 638-648 11 p., ddx431.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
Exploring the Role of PGC-1α in Defining Nuclear Organisation in Skeletal Muscle Fibres
Ross, J. A., Pearson, A., Levy, Y., Cardel, B., Handschin, C. & Ochala, Julien, 1 Jun 2017, In: Journal of Cellular Physiology. 232, 6, p. 1270-1274 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Current and future therapeutic approaches to the congenital myopathies
Jungbluth, H., Ochala, Julien, Treves, S. & Gautel, M., Apr 2017, In: Seminars in Cell and Developmental Biology. 64, p. 191-200 10 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
Novel myosin-based therapies for congenital cardiac and skeletal myopathies
Ochala, Julien & Sun, Y. B., 1 Oct 2016, In: Journal of Medical Genetics. 53, 10, p. 651-654 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myopathy-inducing mutation H40Y in ACTA1 hampers actin filament structure and function
Chan, C., Fan, J., Messer, A. E., Marston, S. B., Iwamoto, H. & Ochala, Julien, 1 Aug 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 8, p. 1453-1458 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 240294914
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Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
65
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Myofibre hyper-contractility in horses expressing the myosin heavy chain myopathy mutation, myh1e321g
Research output: Contribution to journal › Journal article › Research › peer-review
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35
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Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption
Research output: Contribution to journal › Journal article › Research › peer-review
Published