Jens Bukh
Professor
Virology
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-13-84
Member of:
- 2014
- Published
Highly efficient infectious cell culture of three hepatitis C virus genotype 2b strains and sensitivity to lead protease, nonstructural protein 5A, and polymerase inhibitors
Ramirez, S., Li, Y., Jensen, S. B., Pedersen, J., Gottwein, Judith Margarete & Bukh, Jens, Feb 2014, In: Hepatology. 59, 2, p. 395-407 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus
Prentø, Jannick, Serre, S. B. N., Ramirez, S., Nicosia, A. & Bukh, Jens, Feb 2014, In: Journal of Virology. 88, 3, p. 1725-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource
Smith, D. B., Bukh, Jens, Kuiken, C., Muerhoff, A. S., Rice, C. M., Stapleton, J. T. & Simmonds, P., Jan 2014, In: Hepatology. 59, 1, p. 318-27 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in denmark: identification of viral resistance mutations
Sølund, C., Krarup, H., Ramirez Almeida, Santseharay, Thielsen, P., Røge, B. T., Lunding, S., Barfod, Toke Seierøe, Madsen, Lone Galmstrup, Tarp, B., Christensen, P. B., Gerstoft, Jan, Laursen, A. L., Bukh, Jens, Weis, Nina & DANHEP Group, D. G., 2014, In: PLOS ONE. 9, 12, p. 1-20 20 p., e113034.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Efficient cell culture system for hepatitis C virus genotype 5A: Patent #: 8,618,275
Jensen, T. B., Gottwein, Judith Margarete, Scheel, T. K. H., Eugen-Olsen, J. & Bukh, Jens, 31 Dec 2013, IPC No. C07H 21/00 (20060101); C12N 7/00 (20060101); A61K 39/295 (20060101); A61K 39/12 (20060101); A61K 39/29 (20060101), Patent No. WO2008/141651, 27 Nov 2008, Priority date 19 May 2008, Priority No. PCT/DK2008/050113Research output: Patent
- Published
Adapted J6/JFH1-based Hepatitis C virus recombinants with genotype-specific NS4A show similar efficacies against lead protease inhibitors, alpha interferon, and a putative NS4A inhibitor
Gottwein, Judith Margarete, Jensen, S. B., Serre, S. B. N., Ghanem, L., Scheel, Troels Kasper Høyer, Jensen, T. B., Krarup, H., Uzcategui, N., Mikkelsen, L. S. & Bukh, Jens, Dec 2013, In: Antimicrobial Agents and Chemotherapy. 57, 12, p. 6034-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of alpha interferon-induced envelope mutations of hepatitis C virus in vitro associated with increased viral fitness and interferon resistance
Serre, S. B. N., Krarup, H. B., Bukh, Jens & Gottwein, Judith Margarete, Dec 2013, In: Journal of Virology. 87, 23, p. 12776-93 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent human hepatitis B virus infection in cynomolgus monkeys: a novel animal model in the search for a cure?
Bukh, Jens, Lanford, R. E. & Purcell, R. H., Nov 2013, In: Hepatology. 58, 5, p. 1533-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient cell culture system for hepatitis C virus genotype 6A: Patent #: 8,569,472
Gottwein, Judith Margarete, Scheel, T. K. H., Jensen, T. B. & Bukh, Jens, 29 Oct 2013, IPC No. C07H 21/00 (20060101); C12N 7/00 (20060101); A61K 39/295 (20060101); A61K 39/12 (20060101); A61K 39/29 (20060101), Patent No. WO2009/080052, 2 Jul 2009, Priority date 19 Dec 2008, Priority No. PCT/DK2008/050332Research output: Patent
- Published
Efficient cell culture system for hepatitis C virus genotype 1a and 1b: Patent #: 8,563,706
Scheel, T. K. H., Gottwein, Judith Margarete, Prentø, Jannick, Jensen, T. B. & Bukh, Jens, 22 Oct 2013, IPC No. C07H 21/00 (20060101); A61K 39/29 (20060101); A61K 39/12 (20060101); A61K 39/295 (20060101); C12N 7/00 (20060101), Patent No. WO2009/080053, 2 Jul 2009, Priority date 19 Dec 2008, Priority No. PCT/DK2008/050333Research output: Patent
ID: 12437
Most downloads
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415
downloads
Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
Research output: Contribution to journal › Review › Research › peer-review
Published -
383
downloads
Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
345
downloads
Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry
Research output: Contribution to journal › Review › Research › peer-review
Published